Publications by Researcher: Metcalfe, RD

2019 The structure of the Plasmodium falciparum 20S proteasome in complex with the PA28 activator
Acta Crystallographica A-foundation And Advances
Metcalfe, RD Xie, SC Hanssen, E Yang, T Gillett, DL Leis, A Morton, CJ Kuiper, MJ Parker, MW Spillman, NJ Wong, W Tsu, C Dick, LR Griffin, MDW Tilley, L
2019 The structure of the PA28-20S proteasome complex from Plasmodium falciparum and implications for proteostasis
Nature Microbiology
Xie, SC Metcalfe, RD Hanssen, E Yang, T Gillett, DL Leis, AP Morton, CJ Kuiper, MJ Parker, MW Spillman, NJ Wong, W Tsu, C Dick, LR Griffin, MDW Tilley, L
2020 The structure of the extracellular domains of human interleukin 11? receptor reveals mechanisms of cytokine engagement
Journal Of Biological Chemistry
Metcalfe, RD Aizel, K Zlatic, CO Nguyen, PM Morton, CJ Lio, DSS Cheng, HC Dobson, RCJ Parker, MW Gooley, PR Putoczki, TL Griffin, MDW
2021 Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome
Proceedings Of The National Academy Of Sciences Of The United States Of America
Xie, SC Metcalfe, RD Mizutani, H Puhalovich, T Hanssen, E Morton, CJ Du, YW Dogovski, C Huang, SC Ciavarri, J Hales, P Griffin, RJ Cohen, LH Chuang, BC Wittlin, S Deni, I Yeo, T Ward, KE Barry, DC Liu, BY Gillett, DL Crespo-Fernandez, BF Ottilie, S Mittal, N Churchyard, A Ferguson, D Aguiar, ACC Guido, RVC Baum, J Hanson, KK Winzeler, EA Gamo, FJ Fidock, DA Baud, D Parker, MW Brand, S Dick, LR Griffin, MDW Gould, AE Tilley, L
2021 Functional and structural analysis of cytokine-selective IL6ST defects that cause recessive hyper-IgE syndrome
Journal Of Allergy And Clinical Immunology
Chen, YH Zastrow, DB Metcalfe, RD Gartner, L Krause, F Morton, CJ Marwaha, S Fresard, L Huang, Y Zhao, CL McCormack, C Bick, D Worthey, EA Eng, CM Gold, J Montgomery, SB Fisher, PG Ashley, EA Wheeler, MT Parker, MW Shanmugasundaram, V Putoczki, TL Schmidt-Arras, D Laurence, A Bernstein, JA Griffin, MDW Uhlig, HH