Publications by Researcher: Chalk, AM

Year	Title	Author(s)
2013	Modeling distinct osteosarcoma subtypes in vivo using Cre:lox and lineage-restricted transgenic shRNA Bone	Mutsaers, AJ Ng, AJM Baker, EK Russell, MR Chalk, AM Wall, M Liddicoat, BJJ Ho, PWM Slavin, JL Goradia, A Martin, TJ Purton, LE Dickins, RA Walkley, CR
2014	The SKI proto-oncogene enhances the in vivo repopulation of hematopoietic stem cells and causes myeloproliferative disease Haematologica	Singbrant, S Wall, M Moody, J Karlsson, G Chalk, AM Liddicoat, B Russell, MR Walkley, CR Karlsson, S
2014	The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis Journal Of Clinical Investigation	Smeets, MF DeLuca, E Wall, M Quach, JM Chalk, AM Deans, AJ Heierhorst, J Purton, LE Izon, DJ Walkley, CR
2015	RNA EDITING RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself Science	Liddicoat, BJ Piskol, R Chalk, AM Ramaswami, G Higuchi, M Hartner, JC Li, JB Seeburg, PH Walkley, CR
2015	Wnt inhibitory factor 1 (WIF1) is a marker of osteoblastic differentiation stage and is not silenced by DNA methylation in osteosarcoma Bone	Baker, EK Taylor, S Gupte, A Chalk, AM Bhattacharya, S Green, AC Martin, TJ Strbenac, D Robinson, MD Purton, LE Walkley, CR
2015	Knockdown of PTHR1 in osteosarcoma cells decreases invasion and growth and increases tumor differentiation in vivo Oncogene	Ho, PWM Goradia, A Russell, MR Chalk, AM Milley, KM Baker, EK Danks, JA Slavin, JL Walia, M Crimeen-Irwin, B Dickins, RA Martin, TJ Walkley, CR
2015	Knockdown of PTHR1 in osteosarcoma cells decreases invasion and growth and increases tumor differentiation in vivo. Oncogene	Ho, PW Goradia, A Russell, MR Chalk, AM Milley, KM Baker, EK Danks, JA Slavin, JL Walia, M Crimeen-Irwin, B Dickins, RA Martin, TJ Walkley, CR
2015	Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research	Gupte, A Baker, EK Wan, SS Stewart, E Loh, A Shelat, AA Gould, CM Chalk, AM Taylor, S Lackovic, K Karlstrom, A Mutsaers, AJ Desai, J Madhamshettiwar, PB Zannettino, AC Burns, C Huang, DC Dyer, MA Simpson, KJ Walkley, CR
2015	BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells Sci Rep	Baker, EK Taylor, S Gupte, A Sharp, PP Walia, M Walsh, NC Zannettino, ACW Chalk, AM Burns, CJ Walkley, CR
2015	Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma Clin. Cancer Res.	Gupte, A Baker, EK Wan, SS Stewart, E Loh, A Shelat, AA Gould, CM Chalk, AM Taylor, S Lackovic, K Karlstrom, A Mutsaers, AJ Desai, J Madhamshettiwar, PB Zannettino, ACW Burns, C Huang, DCS Dyer, MA Simpson, KJ Walkley, CR
2016	Adenosine-to-inosine RNA editing by ADAR1 is essential for normal murine erythropoiesis Exp Hematol	Li, JB Piskol, R Wall, M Lu, J Hartner, JC Sankaran, VG Orkin, SH Liddicoat, BJ Kingsley, PD Palis, J Chalk, AM Seeburg, PH Ramaswami, G Purton, LE Walkley, CR
2016	Increased miR-155-5p and reduced miR-148a-3p contribute to the suppression of osteosarcoma cell death Oncogene	Bhattacharya, S Chalk, AM Ng, AJM Martin, TJ Zannettino, AC Purton, LE Lu, J Baker, EK Walkley, CR
2016	ADAR1, inosine and the immune sensing system: distinguishing self from non-self Wiley Interdiscip. Rev.-rna	Liddicoat, BJ Chalk, AM Walkley, CR
2016	Activation of PTHrP-cAMP-CREB1 signaling following p53 loss is essential for osteosarcoma initiation and maintenance Elife	Walia, MK Ho, PMW Taylor, S Ng, AJM Gupte, A Chalk, AM Zannettino, ACW Martin, TJ Walkely, CR
2017	Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis Genome Biol.	Heraud-Farlow, JE Chalk, AM Linder, SE Li, Q Taylor, S White, JM Pang, L Liddicoat, BJ Gupte, A Li, JB Walkley, CR
2018	Srsf2(P95H) initiates myeloid bias and myelodysplastic/myeloproliferative syndrome from hemopoietic stem cells Blood	Smeets, MF Tan, SY Xu, JJ Anande, G Unnikrishnan, A Chalk, AM Taylor, SR Pimanda, JE Wall, M Purton, LE Walkley, CR
2019	The majority of A-to-I RNA editing is not required for mammalian homeostasis Genome Biology	Chalk, AM Taylor, S Heraud-Farlow, JE Walkley, CR
2019	Defining the functions of adenosine-to-inosine RNA editing through hematology Current Opinion In Hematology	Heraud-Farlow, JE Chalk, AM Walkley, CR
2020	Hematopoietic stem and progenitor cell-restricted Cdx2 expression induces transformation to myelodysplasia and acute leukemia Nature Communications	Vu, T Straube, J Porter, AH Bywater, M Song, A Ling, V Cooper, L Pali, G Bruedigam, C Jacquelin, S Green, J Magor, G Perkins, A Chalk, AM Walkley, CR Heidel, FH Mukhopadhyay, P Cloonan, N Groschel, S Mallm, JP Frohling, S Scholl, C Lane, SW
2021	The characterization of distinct populations of murine skeletal cells that have different roles in B lymphopoiesis Blood	Green, AC Tjin, G Lee, SC Chalk, AM Straszkowski, L Kwang, D Baker, EK Quach, JM Kimura, T Wu, JY Purton, LE