Publications by Researcher: Heierhorst, J

2012 The Zinc-finger protein ASCIZ regulates B cell development via DYNLL1 and Bim
Journal Of Experimental Medicine
Jurado, S Gleeson, K O’Donnell, K Izon, DJ Walkley, CR Strasser, A Tarlinton, DM Heierhorst, J
2012 ATM Substrate Chk2-interacting Zn2+ Finger (ASCIZ) Is a Bi-functional Transcriptional Activator and Feedback Sensor in the Regulation of Dynein Light Chain (DYNLL1) Expression
Journal Of Biological Chemistry
Jurado, S Conlan, LA Baker, EK Ng, JL Tenis, N Hoch, NC Gleeson, K Smeets, M Izon, D Heierhorst, J
2013 Suppression of Chromosome Healing and Anticheckpoint Pathways in Yeast Postsenescence Survivors
Lai, XN Heierhorst, J
2013 Yeast hEST1A/B (SMG5/6)-Like Proteins Contribute to Environment-Sensing Adaptive Gene Expression Responses
G3-genes Genomes Genetics
Lai, XN Beilharz, T Au, WC Hammet, A Preiss, T Basrai, MA Heierhorst, J
2013 Molecular Basis of the Essential S Phase Function of the Rad53 Checkpoint Kinase
Molecular And Cellular Biology
Hoch, NC Chen, ESW Buckland, R Wang, SC Fazio, A Hammet, A Pellicioli, A Chabes, A Tsai, MD Heierhorst, J
2013 Essential Developmental, Genomic Stability, and Tumour Suppressor Functions of the Mouse Orthologue of hSSB1/NABP2
Plos Genetics
Shi, W Bain, AL Schwer, B Al-Ejeh, F Smith, C Wong, L Chai, H Miranda, MS Ho, U Kawaguchi, M Miura, Y Finnie, JW Wall, M Heierhorst, J Wicking, C Spring, KJ Alt, FW Khanna, KK
2014 Use of Quantitative Mass Spectrometric Analysis to Elucidate the Mechanisms of Phospho-priming and Auto-activation of the Checkpoint Kinase Rad53 in Vivo
Molecular & Cellular Proteomics
Chen, ESW Hoch, NC Wang, SC Pellicioli, A Heierhorst, J Tsai, MD
2014 The Novel Zinc Finger Protein dASCIZ Regulates Mitosis in Drosophila via an Essential Role in Dynein Light-Chain Expression
Zaytseva, O Tenis, N Mitchell, N Kanno, S Yasui, A Heierhorst, J Quinn, LM
2014 The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis
Journal Of Clinical Investigation
Smeets, MF DeLuca, E Wall, M Quach, JM Chalk, AM Deans, AJ Heierhorst, J Purton, LE Izon, DJ Walkley, CR
2016 The Transcription Factor ASCIZ and Its Target DYNLL1 Are Essential for the Development and Expansion of MYC-Driven B Cell Lymphoma
Cell Reports
Wong, DM Li, LL Jurado, S King, A Bamford, R Wall, M Walia, MK Kelly, GL Walkley, CR Tarlinton, DM Strasser, A Heierhorst, J
2017 Quantitative Analysis of Yeast Checkpoint Protein Kinase Activity by Combined Mass Spectrometry Enzyme Assays
Methods Enzymol.
Hoch, NC Chen, ESW Tsai, MD Heierhorst, J
2017 Mechanism of Ubiquitination and Deubiquitination in the Fanconi Anemia Pathway
Mol. Cell
van Twest, S Murphy, VJ Hodson, C Tan, WN Swuec, P O’Rourke, JJ Heierhorst, J Crismani, W Deans, AJ
2017 ASCIZ/ATMIN is dispensable for ATM signaling in response to replication stress
Dna Repair
Liu, R King, A Hoch, NC Chang, C Kelly, GL Deans, AJ Heierhorst, J
2017 Dynein light chain regulates adaptive and innate B cell development by distinctive genetic mechanisms
Plos Genet.
King, A Li, LL Wong, DM Liu, R Bamford, R Strasser, A Tarlinton, DM Heierhorst, J
2018 Proapoptotic BIM Impacts B Lymphoid Homeostasis by Limiting the Survival of Mature B Cells in a Cell-Autonomous Manner
Front. Immunol.
Liu, R King, A Bouillet, P Tarlinton, DM Strasser, A Heierhorst, J
2018 Multivalency regulates activity in an intrinsically disordered transcription factor
Clark, S Myers, JB King, A Fiala, R Novacek, J Pearce, G Heierhorst, J Reichow, SL Barbar, EJ
2018 The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity
Nat. Commun.
Becker, JR Cuella-Martin, R Barazas, M Liu, R Oliveira, C Oliver, AW Bilham, K Holt, AB Blackford, AN Heierhorst, J Jonkers, J Rottenberg, S Chapman, JR
2019 Dynll1 is essential for development and promotes endochondral bone formation by regulating intraflagellar dynein function in primary cilia
Human Molecular Genetics
King, A Hoch, NC McGregor, NE Sims, NA Smyth, IM Heierhorst, J
2019 ATP-dependent helicase activity is dispensable for the physiological functions of Recql4
Plos Genetics
Castillo-Tandazo, W Smeets, MF Murphy, V Liu, R Hodson, C Heierhorst, J Deans, AJ Walkley, CR
2021 The ASCIZ-DYNLL1 Axis Is Essential for TLR4-Mediated Antibody Responses and NF-kappa B Pathway Activation
Molecular And Cellular Biology
Liu, R King, A Tarlinton, D Heierhorst, J