Publications by Researcher: Miles, LA

YearTitleAuthor(s)
2012 Structural approaches to probing metal interaction with proteins
Journal Of Inorganic Biochemistry
Parker, LJ Ascher, DB Gao, C Miles, LA Harris, HH Parker, MW
2013 Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation
Scientific Reports
Miles, LA Crespi, GAN Doughty, L Parker, MW
2013 Synthetic dityrosine-linked beta-amyloid dimers form stable, soluble, neurotoxic oligomers
Chemical Science
Kok, WM Cottam, JM Ciccotosto, GD Miles, LA Karas, JA Scanlon, DB Roberts, BR Parker, MW Cappai, R Barnham, KJ Hutton, CA
2014 Crystallization and preliminary X-ray diffraction analysis of the Fab portion of the Alzheimer's disease immunotherapy candidate bapineuzumab complexed with amyloid-beta
Acta Crystallographica Section F-structural Biology And Crystallization Communications
Crespi, GAN Ascher, DB Parker, MW Miles, LA
2014 Anti-A beta antibody target engagement: a response to Siemers et al.
Acta Neuropathologica
Watt, AD Crespi, GAN Down, RA Ascher, DB Gunn, A Perez, KA McLean, CA Villemagne, VL Parker, MW Barnham, KJ Miles, LA
2014 Do current therapeutic anti-A beta antibodies for Alzheimer's disease engage the target?
Acta Neuropathologica
Watt, AD Crespi, GAN Down, RA Ascher, DB Gunn, A Perez, KA McLean, CA Villemagne, VL Parker, MW Barnham, KJ Miles, LA
2015 Molecular basis for mid-region amyloid-beta capture by leading Alzheimer's disease immunotherapies
Scientific Reports
Crespi, GAN Hermans, SJ Parker, MW Miles, LA
2015 Abeta targets of the biosimilar antibodies of Bapineuzumab, Crenezumab, Solanezumab in comparison to an antibody against N-trunc
Acta Neuropathologica
Bouter Y Noguerola JSL Tucholla P Crespi GAN Parker, MW Wiltfang J Miles, LA Bayer TA
2015 Abeta targets of the biosimilar antibodies of Bapineuzumab, Crenezumab, Solanezumab in comparison to an antibody against N-truncated Abeta in sporadic Alzheimer disease cases and mouse models
Acta Neuropathol.
Bouter, Y Noguerola, JSL Tucholla, P Crespi, GAN Parker, MW Wiltfang, J Miles, LA Bayer, TA
2017 Ex vivo O-18-labeling mass spectrometry identifies a peripheral amyloid beta clearance pathway
Mol. Neurodegener.
Portelius, E Mattsson, N Pannee, J Zetterberg, H Gisslen, M Vanderstichele, H Gkanatsiou, E Crespi, GAN Parker, MW Miles, LA Gobom, J Blennow, K
2017 Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability
Nucleic Acids Res.
Gillinder, KR Ilsley, MD Nebor, D Sachidanandam, R Lajoie, M Magor, GW Tallack, MR Bailey, T Landsberg, MJ Mackay, JP Parker, MW Miles, LA Graber, JH Peters, LL Bieker, JJ Perkins, AC
2017 Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites
Nat. Commun.
Braig, D Nero, TL Koch, HG Kaiser, B Wang, XW Thiele, JR Morton, CJ Zeller, J Kiefer, J Potempa, LA Mellett, NA Miles, LA Du, XJ Meikle, PJ Huber-Lang, M Stark, GB Parker, MW Peter, K Eisenhardt, SU
2019 Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes A beta Phagocytosis
Iscience
Miles, LA Hermans, SJ Crespi, GAN Gooi, JH Doughty, L Nero, TL Markulic, J Ebneth, A Wroblowski, B Oehlrich, D Trabanco, AA Rives, ML Royaux, I Hancock, NC Parker, MW
2020 N-terminal heterogeneity of parenchymal and vascular amyloid-beta deposits in Alzheimer's disease
Neuropathology And Applied Neurobiology
Zampar, S Klafki, HW Sritharen, K Bayer, TA Wiltfang, J Rostagno, A Ghiso, J Miles, LA Wirths, O