Publications by Researcher: Nero, TL

Year	Title	Author(s)
2012	PEGylation of a proprotein convertase peptide inhibitor for vaginal route of drug delivery: In vitro bioactivity, stability and in vivo pharmacokinetics Peptides	Ho, HT Nero, TL Singh, H Parker, MW Nie, GY
2012	The GM-CSF/IL-3/IL-5 cytokine receptor family: from ligand recognition to initiation of signaling Immunological Reviews	Broughton, SE Dhagat, U Hercus, TR Nero, TL Grimbaldeston, MA Bonder, CS Lopez, AF Parker, MW
2013	Small Molecule Proprotein Convertase Inhibitors for Inhibition of Embryo Implantation Plos One	Ho, HT Singh, H Heng, S Nero, TL Paule, S Parker, MW Johnson, AT Jiao, GS Nie, GY
2013	Signalling by the beta c family of cytokines Cytokine & Growth Factor Reviews	Hercus, TR Dhagat, U Kan, WLT Broughton, SE Nero, TL Perugini, M Sandow, JJ D’Andrea, RJ Ekert, PG Hughes, T Parker, MW Lopez, AF
2013	Characterization of pathogenic human monoclonal autoantibodies against GM-CSF Proceedings Of The National Academy Of Sciences Of The United States Of America	Wang, YN Thomson, CA Allan, LL Jackson, LM Olson, M Hercus, TR Nero, TL Turner, A Parker, MW Lopez, AL Waddell, TK Anderson, GP Hamilton, JA Schrader, JW
2013	Targeting acute myeloid leukemia by dual inhibition of PI3K signaling and Cdk9-mediated Mcl-1 transcription Blood	Thomas, D Powell, JA Vergez, F Segal, DH Nguyen, NYN Baker, A Teh, TC Barry, EF Sarry, JE Lee, EM Nero, TL Jabbour, AM Pomilio, G Green, BD Manenti, S Glaser, SP Parker, MW Lopez, AF Ekert, PG Lock, RB Huang, DCS Nilsson, SK Recher, C Wei, AH Guthridge, MA
2014	Crystallisation and preliminary X-ray diffraction analysis of the Interleukin-3 alpha receptor bound to Fab fragment of antibody Acta Crystallogr F Struct Biol Commun.	Lopez, AF Owczarek, CM Wilson, NJ Dhagat, U Nash, AD Nero, TL Scotney, PD Hercus, TR Fabri, LJ Broughton, SE Hardy, MP Parker, MW
2014	Oncogenic protein interfaces: small molecules, big challenges Nature Reviews Cancer	Nero, TL Morton, CJ Holien, JK Wielens, J Parker, MW
2014	Activity-Modulating Monoclonal Antibodies to the Human Serine Protease HtrA3 Provide Novel Insights into Regulating HtrA Proteol Plos One	Singh, H Nero, TL Wang, Y Parker, MW Nie, GY
2014	Crystallization and preliminary X-ray diffraction analysis of the interleukin-3 alpha receptor bound to the Fab fragment of antibody CSL362 Acta Crystallographica Section F-structural Biology And Crystallization Communications	Broughton, SE Hercus, TR Nero, TL Dhagat, U Owczarek, CM Hardy, MP Fabri, LJ Scotney, PD Nash, AD Wilson, NJ Lopez, AF Parker, MW
2014	Crystallization and preliminary X-ray diffraction analysis of the interleukin-3 alpha receptor bound to the Fab fragment of anti Acta Crystallographica Section F-structural Biology Communications	Broughton, SE Hercus, TR Nero, TL Dhagat, U Owczarek, CM Hardy, MP Fabri, LJ Scotney, PD Nash, AD Wilson, NJ Lopez, AF Parker, MW
2014	Potent hepatitis C inhibitors bind directly to NS5A and reduce its affinity for RNA Scientific Reports	Ascher, DB Wielens, J Nero, TL Doughty, L Morton, CJ Parker, MW
2015	The beta c receptor family - Structural insights and their functional implications Cytokine	Broughton, SE Nero, TL Dhagat, U Kan, WL Hercus, TR Tvorogov, D Lopez, AF Parker, MW
2015	Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators Journal Of Experimental Medicine	Flierl, U Nero, TL Lim, B Arthur, JF Yao, Y Jung, SM Gitz, E Pollitt, AY Zaldivia, MTK Jandrot-Perrus, M Schafer, A Nieswandt, B Andrews, RK Parker, MW Gardiner, EE Peter, K
2015	Discovery and SAR of novel pyrazolo[1,5-a]pyrimidines as inhibitors of CDK9 Bioorganic & Medicinal Chemistry	Phillipson, LJ Segal, DH Nero, TL Parker, MW Wan, SS de Silva, M Guthridge, MA Wei, AH Burns, CJ
2016	Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling Structure	Broughton, SE Hercus, TR Nero, TL Dottore, M McClure, BJ Dhagat, U Taing, H Gorman, MA King-Scott, J Lopez, AF Parker, MW
2017	Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites Nat. Commun.	Braig, D Nero, TL Koch, HG Kaiser, B Wang, XW Thiele, JR Morton, CJ Zeller, J Kiefer, J Potempa, LA Mellett, NA Miles, LA Du, XJ Meikle, PJ Huber-Lang, M Stark, GB Parker, MW Peter, K Eisenhardt, SU
2018	Protein structure and computational drug discovery Biochem. Soc. Trans.	Nero, TL Parker, MW Morton, CJ
2018	Targeting of C-type lectin-like receptor 2 or P2Y12 for the prevention of platelet activation by immunotherapeutic CpG oligodeoxynucleotides: comment J. Thromb. Haemost.	Flierl, U Nero, TL Lim, B Andrews, RK Parker, MW Gardiner, EE Peter, K
2018	A dual role for the N-terminal domain of the IL-3 receptor in cell signalling Nat. Commun.	Broughton, SE Hercus, TR Nero, TL Kan, WL Barry, EF Dottore, M Shing, KSCT Morton, CJ Dhagat, U Hardy, MP Wilson, NJ Downton, MT Schieber, C Hughes, TP Lopez, AF Parker, MW
2018	EPO does not promote interaction between the erythropoietin and beta-common receptors Sci Rep	Shing, KSCT Broughton, SE Nero, TL Gillinder, K Ilsley, MD Ramshaw, H Lopez, AF Griffin, MDW Parker, MW Perkins, AC Dhagat, U
2018	The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities Mabs	Dhagat, U Hercus, TR Broughton, SE Nero, TL Shing, KSCT Barry, EF Thomson, CA Bryson, S Pai, EF McClure, BJ Schrader, JW Lopez, AF Parker, MW
2018	Role of the beta Common (beta c) Family of Cytokines in Health and Disease Cold Spring Harbor Perspect. Biol.	Hercus, TR Kan, WLT Broughton, SE Tvorogov, D Ramshaw, HS Sandow, JJ Nero, TL Dhagat, U Thompson, EJ Shing, KSCT McKenzie, DR Wilson, NJ Owczarek, CM Vairo, G Nash, AD Tergaonkar, V Hughes, T Ekert, PG Samuel, MS Bonder, CS Grimbaldeston, MA Parker, MW Lopez, AF
2019	A Family of Dual-Activity Glycosyltransferase-Phosphorylases Mediates Mannogen Turnover and Virulence in Leishmania Parasites Cell Host & Microbe	Sernee, MF Ralton, JE Nero, TL Sobala, LF Kloehn, J Vieira-Lara, MA Cobbold, SA Stanton, L Pires, DEV Hanssen, E Males, A Ward, T Bastidas, LM van der Peet, PL Parker, MW Ascher, DB Williams, SJ Davies, GJ McConville, MJ
2019	EPO does not promote interaction between the erythropoietin and beta-common receptors (vol 8, 12457, 2018) Scientific Reports	Shing, KSCT Broughton, SE Nero, TL Gillinder, K Ilsley, MD Ramshaw, H Lopez, AF Griffin, MDW Parker, MW Perkins, AC Dhagat, U
2019	Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth Embo Molecular Medicine	Thilakasiri, P Huynh, J Poh, AR Tan, CW Nero, TL Tran, K Parslow, AC Afshar-Sterle, S Baloyan, D Hannan, NJ Buchert, M Scott, AM Griffin, MDW Hollande, F Parker, MW Putoczki, TL Ernst, M Chand, AL
2019	Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes A beta Phagocytosis Iscience	Miles, LA Hermans, SJ Crespi, GAN Gooi, JH Doughty, L Nero, TL Markulic, J Ebneth, A Wroblowski, B Oehlrich, D Trabanco, AA Rives, ML Royaux, I Hancock, NC Parker, MW
2020	Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK beta 1 isoforms Nature Metabolism	Pinkosky, SL Scott, JW Desjardins, EM Smith, BK Day, EA Ford, RJ Langendorf, CG Ling, NXY Nero, TL Loh, K Galic, S Hoque, A Smiles, WJ Ngoei, KRW Parker, MW Yan, Y Melcher, K Kemp, BE Oakhill, JS Steinberg, GR
2021	Messing with beta c: A unique receptor with many goals Seminars In Immunology	Kan, WL Shing, KSCT Nero, TL Hercus, TR Tvorogov, D Parker, MW Lopez, AF
2021	Repurposing of drugs as STAT3 inhibitors for cancer therapy Seminars In Cancer Biology	Thilakasiri, PS Dmello, RS Nero, TL Parker, MW Ernst, M Chand, AL