Year | Title | Author(s) |
2014 |
Dual mechanism of interleukin-3 receptor blockade by an anti-cancer antibody.
Cell Rep |
Busfield, SJ Hardy, MP Braley, H Hartman, D Parker, MW Hercus, TR Huynh, H Scotney, PD Wilson, NJ Dottore, M Dhagat, U Nash, AD McClure, BJ Kan, WL Owczarek, CM Broughton, SE Barry, EF Lopez, AF |
2016 |
Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling
Structure |
Broughton, SE Hercus, TR Nero, TL Dottore, M McClure, BJ Dhagat, U Taing, H Gorman, MA King-Scott, J Lopez, AF Parker, MW |
2016 |
CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common beta chain of the IL-3, GM-CSF and IL-5 receptors
Mabs |
Panousis, C Dhagat, U Edwards, KM Rayzman, V Hardy, MP Braley, H Gauvreau, GM Hercus, TR Smith, S Sehmi, R McMillan, L Dottore, M McClure, BJ Fabri, LJ Vairo, G Lopez, AF Parker, MW Nash, AD Wilson, NJ Wilson, MJ Owczarek, CM |
2018 |
Accumulation of JAK activation loop phosphorylation is linked to type I JAK inhibitor withdrawal syndrome in myelofibrosis
Sci. Adv. |
Tvorogov, D Thomas, D Liau, NPD Dottore, M Barry, EF Lathi, M Kan, WL Hercus, TR Stomski, F Hughes, TP Tergaonkar, V Parker, MW Ross, DM Majeti, R Babon, JJ Lopez, AF |
2018 |
A dual role for the N-terminal domain of the IL-3 receptor in cell signalling
Nat. Commun. |
Broughton, SE Hercus, TR Nero, TL Kan, WL Barry, EF Dottore, M Shing, KSCT Morton, CJ Dhagat, U Hardy, MP Wilson, NJ Downton, MT Schieber, C Hughes, TP Lopez, AF Parker, MW |