Publications by Researcher: Broughton, SE

Year	Title	Author(s)
2012	Biased T Cell Receptor Usage Directed against Human Leukocyte Antigen DQ8-Restricted Gliadin Peptides Is Associated with Celiac Disease Immunity	Broughton, SE Petersen, J Theodossis, A Scally, SW Loh, KL Thompson, A van Bergen, J Kooy-Winkelaar, Y Henderson, KN Beddoe, T Tye-Din, JA Mannering, SI Purcell, AW McCluskey, J Anderson, RP Koning, F Reid, HH Rossjohn, J
2012	Cytokine receptor activation at the cell surface Current Opinion In Structural Biology	Broughton, SE Hercus, TR Lopez, AF Parker, MW
2012	The GM-CSF/IL-3/IL-5 cytokine receptor family: from ligand recognition to initiation of signaling Immunological Reviews	Broughton, SE Dhagat, U Hercus, TR Nero, TL Grimbaldeston, MA Bonder, CS Lopez, AF Parker, MW
2012	The GM-CSF receptor family: Mechanism of activation and implications for disease Growth Factors	Hercus, TR Broughton, SE Ekert, PG Ramshaw, HS Perugini, M Grimbaldeston, M Woodcock, JM Thomas, D Pitson, S Hughes, T D’Andrea, RJ Parker, MW Lopez, AF
2013	Signalling by the beta c family of cytokines Cytokine & Growth Factor Reviews	Hercus, TR Dhagat, U Kan, WLT Broughton, SE Nero, TL Perugini, M Sandow, JJ D’Andrea, RJ Ekert, PG Hughes, T Parker, MW Lopez, AF
2014	Dual mechanism of interleukin-3 receptor blockade by an anti-cancer antibody. Cell Rep	Owczarek, CM Broughton, SE Barry, EF Busfield, SJ Hardy, MP Braley, H Hartman, D Parker, MW Hercus, TR Huynh, H Scotney, PD Wilson, NJ Dottore, M Dhagat, U Nash, AD McClure, BJ Kan, WL Lopez, AF
2014	Crystallisation and preliminary X-ray diffraction analysis of the Interleukin-3 alpha receptor bound to Fab fragment of antibody Acta Crystallogr F Struct Biol Commun.	Broughton, SE Hardy, MP Lopez, AF Owczarek, CM Wilson, NJ Dhagat, U Nash, AD Nero, TL Scotney, PD Hercus, TR Fabri, LJ Parker, MW
2014	Crystallization and preliminary X-ray diffraction analysis of the interleukin-3 alpha receptor bound to the Fab fragment of antibody CSL362 Acta Crystallographica Section F-structural Biology And Crystallization Communications	Broughton, SE Hercus, TR Nero, TL Dhagat, U Owczarek, CM Hardy, MP Fabri, LJ Scotney, PD Nash, AD Wilson, NJ Lopez, AF Parker, MW
2014	Crystallization and preliminary X-ray diffraction analysis of the interleukin-3 alpha receptor bound to the Fab fragment of anti Acta Crystallographica Section F-structural Biology Communications	Broughton, SE Hercus, TR Nero, TL Dhagat, U Owczarek, CM Hardy, MP Fabri, LJ Scotney, PD Nash, AD Wilson, NJ Lopez, AF Parker, MW
2015	The beta c receptor family - Structural insights and their functional implications Cytokine	Broughton, SE Nero, TL Dhagat, U Kan, WL Hercus, TR Tvorogov, D Lopez, AF Parker, MW
2016	Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling Structure	Broughton, SE Hercus, TR Nero, TL Dottore, M McClure, BJ Dhagat, U Taing, H Gorman, MA King-Scott, J Lopez, AF Parker, MW
2018	A dual role for the N-terminal domain of the IL-3 receptor in cell signalling Nat. Commun.	Broughton, SE Hercus, TR Nero, TL Kan, WL Barry, EF Dottore, M Shing, KSCT Morton, CJ Dhagat, U Hardy, MP Wilson, NJ Downton, MT Schieber, C Hughes, TP Lopez, AF Parker, MW
2018	EPO does not promote interaction between the erythropoietin and beta-common receptors Sci Rep	Shing, KSCT Broughton, SE Nero, TL Gillinder, K Ilsley, MD Ramshaw, H Lopez, AF Griffin, MDW Parker, MW Perkins, AC Dhagat, U
2018	The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities Mabs	Dhagat, U Hercus, TR Broughton, SE Nero, TL Shing, KSCT Barry, EF Thomson, CA Bryson, S Pai, EF McClure, BJ Schrader, JW Lopez, AF Parker, MW
2018	Role of the beta Common (beta c) Family of Cytokines in Health and Disease Cold Spring Harbor Perspect. Biol.	Hercus, TR Kan, WLT Broughton, SE Tvorogov, D Ramshaw, HS Sandow, JJ Nero, TL Dhagat, U Thompson, EJ Shing, KSCT McKenzie, DR Wilson, NJ Owczarek, CM Vairo, G Nash, AD Tergaonkar, V Hughes, T Ekert, PG Samuel, MS Bonder, CS Grimbaldeston, MA Parker, MW Lopez, AF
2019	EPO does not promote interaction between the erythropoietin and beta-common receptors (vol 8, 12457, 2018) Scientific Reports	Shing, KSCT Broughton, SE Nero, TL Gillinder, K Ilsley, MD Ramshaw, H Lopez, AF Griffin, MDW Parker, MW Perkins, AC Dhagat, U