Publications by Researcher: Langendorf, CG

YearTitleAuthor(s)
2014 ATP sensitive bi-quinoline activator of the AMP-activated protein kinase
Biochemical And Biophysical Research Communications
Scott, JW Oakhill, JS Ling, NXY Langendorf, CG Foitzik, RC Kemp, BE Issinger, OG
2014 Small Molecule Drug A-769662 and AMP Synergistically Activate Naive AMPK Independent of Upstream Kinase Signaling
Chemistry & Biology
Scott, JW Ling, NM Issa, SMA Dite, TA O’Brien, MT Chen, ZP Galic, S Langendorf, CG Steinberg, GR Kemp, BE Oakhill, JS
2015 Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release
Chem Biol
Thomas, HE Foitzik, R Weng, QP Kemp, BE Graham, KL Langendorf, CG Steinberg, GR Galic, S Issa, SMA Birnberg, NC Scott, JW Dite, TA Kay, TW Ling, NXY Oakhill, JS
2015 Choreography of AMPK activation
Cell Research
Langendorf, CG Kemp, BE
2015 Autophosphorylation of CaMKK2 generates autonomous activity that is disrupted by a T85S mutation linked to anxiety and bipolar disorder
Sci Rep
Scott, JW Park, E Rodriguiz, RM Oakhill, JS Issa, SMA O’Brien, MT Dite, TA Langendorf, CG Wetsel, WC Means, AR Kemp, BE
2015 Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release
Chem. Biol.
Scott, JW Galic, S Graham, KL Foitzik, R Ling, NXY Dite, TA Issa, SMA Langendorf, CG Weng, QP Thomas, HE Kay, TW Birnberg, NC Steinberg, GR Kemp, BE Oakhill, JS
2016 Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding
Nat. Commun.
Langendorf, CG Ngoei, KRW Scott, JW Ling, NXY Issa, SMA Gorman, MA Parker, MW Sakamoto, K Oakhill, JS Kemp, BE
2017 Impact of Genetic Variation on Human CaMKK2 Regulation by Ca2+-Calmodulin and Multisite Phosphorylation
Sci Rep
O’Brien, MT Oakhill, JS Ling, NMXY Langendorf, CG Hoque, A Dite, TA Means, AR Kemp, BE Scott, JW
2017 The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs
Nat. Commun.
Dite, TA Ling, NXY Scott, JW Hoque, A Galic, S Parker, BL Ngoei, KRW Langendorf, CG O’Brien, MT Kundu, M Viollet, B Steinberg, GR Sakamoto, K Kemp, BE Oakhill, JS
2018 Visualizing AMPK Drug Binding Sites Through Crystallization of Full-Length Phosphorylated alpha 2 beta 1 gamma 1 Heterotrimer
Methods Mol. Biol.
Langendorf, CG Oakhill, JS Kemp, BE
2018 AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965
J. Biol. Chem.
Dite, TA Langendorf, CG Hoque, A Galic, S Rebello, RJ Ovens, AJ Lindqvist, LM Ngoei, KRW Ling, NXY Furic, L Kemp, BE Scott, JW Oakhill, JS
2018 Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK alpha 2 beta 2 gamma 1 by the Glucose Importagog SC4
Cell Chem. Biol.
Ngoei, KRW Langendorf, CG Ling, NXY Hoque, A Varghese, S Camerino, MA Walker, SR Bozikis, YE Dite, TA Ovens, AJ Smiles, WJ Jacobs, R Huang, H Parker, MW Scott, JW Rider, MH Foitzik, RC Kemp, BE Baell, JB Oakhill, JS
2018 1,2,6-Thiadiazinones as Novel Narrow Spectrum Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) Inhibitors
Molecules
Asquith, CRM Godoi, PH Counago, RM Laitinen, T Scott, JW Langendorf, CG Oakhill, JS Drewry, DH Zuercher, WJ Koutentis, PA Willson, TM Kalogirou, AS