Publications by Researcher: Galic, S

YearTitleAuthor(s)
2012 Reduced Socs3 expression in adipose tissue protects female mice against obesity-induced insulin resistance
Diabetologia
Palanivel, R Fullerton, MD Galic, S Honeyman, J Hewitt, KA Jorgensen, SB Steinberg, GR
2012 Elevated Hypothalamic TCPTP in Obesity Contributes to Cellular Leptin Resistance (vol 14, pg 684, 2011)
Cell Metabolism
Loh, K Fukushima, A Zhang, XM Galic, S Briggs, D Enriori, PJ Simonds, S Wiede, F Reichenbach, A Hauser, C Sims, NA Bence, KK Zhang, S Zhang, ZY Kahn, BB Neel, BG Andrews, ZB Cowley, MA Tiganis, T
2013 Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin
Nature Medicine
Fullerton, MD Galic, S Marcinko, K Sikkema, S Pulinilkunnil, T Chen, ZP O’Neill, HM Ford, RJ Palanivel, R O’Brien, M Hardie, DG Macaulay, SL Schertzer, JD Dyck, JRB van Denderen, B Kemp, BE Steinberg, GR
2013 Deletion of Skeletal Muscle SOCS3 Prevents Insulin Resistance in Obesity
Diabetes
Jorgensen, SB O’Neill, HM Sylow, L Honeyman, J Hewitt, KA Palanivel, R Fullerton, MD Oberg, L Balendran, A Galic, S van der Poel, C Trounce, IA Lynch, GS Schertzer, JD Steinberg, GR
2014 Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity
Biochemical Journal
Galic, S Sachithanandan, N Kay, TW Steinberg, GR
2014 AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice
Diabetologia
O’Neill, HM Lally, JS Galic, S Thomas, M Azizi, PD Fullerton, MD Smith, BK Pulinilkunnil, T Chen, ZP Samaan, MC Jorgensen, SB Dyck, JRB Holloway, GP Hawke, TJ van Denderen, B Kemp, BE Steinberg, GR
2014 Novel mechanisms of Na+ retention in obesity: phosphorylation of NKCC2 and regulation of SPAK/OSR1 by AMPK
American Journal Of Physiology-renal Physiology
Davies, M Fraser, SA Galic, S Choy, SW Katerelos, M Gleich, K Kemp, BE Mount, PF Power, DA
2014 Activation of AMPK reduces the co-transporter activity of NKCC1
Molecular Membrane Biology
Fraser, SA Davies, M Katerelos, M Gleich, K Choy, SW Steel, R Galic, S Mount, PF Kemp, BE Power, DA
2014 Small Molecule Drug A-769662 and AMP Synergistically Activate Naive AMPK Independent of Upstream Kinase Signaling
Chemistry & Biology
Scott, JW Ling, NM Issa, SMA Dite, TA O’Brien, MT Chen, ZP Galic, S Langendorf, CG Steinberg, GR Kemp, BE Oakhill, JS
2015 Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release
Chem Biol
Graham, KL Langendorf, CG Steinberg, GR Galic, S Issa, SMA Birnberg, NC Scott, JW Dite, TA Kay, TW Ling, NXY Thomas, HE Foitzik, R Weng, QP Kemp, BE Oakhill, JS
2015 Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release
Chem. Biol.
Scott, JW Galic, S Graham, KL Foitzik, R Ling, NXY Dite, TA Issa, SMA Langendorf, CG Weng, QP Thomas, HE Kay, TW Birnberg, NC Steinberg, GR Kemp, BE Oakhill, JS
2015 Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis
Biochem. J.
O’Brien, AJ Villani, LA Broadfield, LA Houde, VP Galic, S Blandino, G Kemp, BE Tsakiridis, T Muti, P Steinberg, GR
2016 Exercise reverses age-related vulnerability of the retina to injury by preventing complement-mediated synapse elimination via a BDNF-dependent pathway
Aging Cell
Chrysostomou, V Galic, S van Wijngaarden, P Trounce, IA Steinberg, GR Crowston, JG
2016 Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease
J. Neurosci.
Bayliss, JA Lemus, MB Stark, R Santos, VV Thompson, A Rees, DJ Galic, S Elsworth, JD Kemp, BE Davies, JS Andrews, ZB
2017 JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis, and Insulin Resistance in Obesity
Diabetes
Litwak, SA Pang, L Galic, S Igoillo-Esteve, M Stanley, WJ Turatsinze, JV Loh, K Thomas, HE Sharma, A Trepo, E Moreno, C Gough, DJ Eizirik, DL de Haan, JB Gurzov, EN
2017 AMPK beta 1 reduces tumor progression and improves survival in p53 null mice
Mol. Oncol.
Houde, VP Donzelli, S Sacconi, A Galic, S Hammill, JA Bramson, JL Foster, RA Tsakiridis, T Kemp, BE Grasso, G Blandino, G Muti, P Steinberg, GR
2017 The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs
Nat. Commun.
Dite, TA Ling, NXY Scott, JW Hoque, A Galic, S Parker, BL Ngoei, KRW Langendorf, CG O’Brien, MT Kundu, M Viollet, B Steinberg, GR Sakamoto, K Kemp, BE Oakhill, JS
2018 AMPK signaling to acetyl-CoA carboxylase is required for fasting- and cold-induced appetite but not thermogenesis
Elife
Galic, S Loh, K Murray-Segal, L Steinberg, GR Andrews, ZB Kemp, BE
2018 Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice
Cell Death Differ.
Wali, JA Galic, S Tan, CYR Gurzov, EN Frazier, AE Connor, T Ge, JJ Pappas, EG Stroud, D Varanasi, LC Selck, C Ryan, MT Thorburn, DR Kemp, BE Krishnamurthy, B Kay, TWH Thomas, HE
2018 AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965
J. Biol. Chem.
Dite, TA Langendorf, CG Hoque, A Galic, S Rebello, RJ Ovens, AJ Lindqvist, LM Ngoei, KRW Ling, NXY Furic, L Kemp, BE Scott, JW Oakhill, JS
2018 Phosphorylation of Acetyl-CoA Carboxylase by AMPK Reduces Renal Fibrosis and Is Essential for the Anti-Fibrotic Effect of Metformin
J. Am. Soc. Nephrol.
Lee, M Katerelos, M Gleich, K Galic, S Kemp, BE Mount, PF Power, DA
2019 Inhibition of Adenosine Monophosphate-Activated Protein Kinase-3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Signaling Leads to Hypercholesterolemia and Promotes Hepatic Steatosis and Insulin Resistance
Hepatol. Commun.
Loh, K Tam, S Murray-Segal, L Huynh, K Meikle, PJ Scott, JW van Denderen, B Chen, ZP Steel, R LeBlond, ND Burkovsky, LA O’Dwyer, C Nunes, JRC Steinberg, GR Fullerton, MD Galic, S Kemp, BE