Publications by Researcher: Galic, S

YearTitleAuthor(s)
2012 Reduced Socs3 expression in adipose tissue protects female mice against obesity-induced insulin resistance
Diabetologia
Palanivel, R Fullerton, MD Galic, S Honeyman, J Hewitt, KA Jorgensen, SB Steinberg, GR
2012 Elevated Hypothalamic TCPTP in Obesity Contributes to Cellular Leptin Resistance (vol 14, pg 684, 2011)
Cell Metabolism
Loh, K Fukushima, A Zhang, XM Galic, S Briggs, D Enriori, PJ Simonds, S Wiede, F Reichenbach, A Hauser, C Sims, NA Bence, KK Zhang, S Zhang, ZY Kahn, BB Neel, BG Andrews, ZB Cowley, MA Tiganis, T
2013 Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin
Nature Medicine
Fullerton, MD Galic, S Marcinko, K Sikkema, S Pulinilkunnil, T Chen, ZP O’Neill, HM Ford, RJ Palanivel, R O’Brien, M Hardie, DG Macaulay, SL Schertzer, JD Dyck, JRB van Denderen, B Kemp, BE Steinberg, GR
2013 Deletion of Skeletal Muscle SOCS3 Prevents Insulin Resistance in Obesity
Diabetes
Jorgensen, SB O’Neill, HM Sylow, L Honeyman, J Hewitt, KA Palanivel, R Fullerton, MD Oberg, L Balendran, A Galic, S van der Poel, C Trounce, IA Lynch, GS Schertzer, JD Steinberg, GR
2014 Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity
Biochemical Journal
Galic, S Sachithanandan, N Kay, TW Steinberg, GR
2014 AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice
Diabetologia
O’Neill, HM Lally, JS Galic, S Thomas, M Azizi, PD Fullerton, MD Smith, BK Pulinilkunnil, T Chen, ZP Samaan, MC Jorgensen, SB Dyck, JRB Holloway, GP Hawke, TJ van Denderen, B Kemp, BE Steinberg, GR
2014 Novel mechanisms of Na+ retention in obesity: phosphorylation of NKCC2 and regulation of SPAK/OSR1 by AMPK
American Journal Of Physiology-renal Physiology
Davies, M Fraser, SA Galic, S Choy, SW Katerelos, M Gleich, K Kemp, BE Mount, PF Power, DA
2014 Small Molecule Drug A-769662 and AMP Synergistically Activate Naive AMPK Independent of Upstream Kinase Signaling
Chemistry & Biology
Scott, JW Ling, NM Issa, SMA Dite, TA O’Brien, MT Chen, ZP Galic, S Langendorf, CG Steinberg, GR Kemp, BE Oakhill, JS
2014 Activation of AMPK reduces the co-transporter activity of NKCC1
Molecular Membrane Biology
Fraser, SA Davies, M Katerelos, M Gleich, K Choy, SW Steel, R Galic, S Mount, PF Kemp, BE Power, DA
2015 Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release
Chem Biol
Scott, JW Dite, TA Kay, TW Ling, NXY Thomas, HE Foitzik, R Weng, QP Kemp, BE Graham, KL Langendorf, CG Steinberg, GR Galic, S Issa, SMA Birnberg, NC Oakhill, JS
2015 Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release
Chem. Biol.
Scott, JW Galic, S Graham, KL Foitzik, R Ling, NXY Dite, TA Issa, SMA Langendorf, CG Weng, QP Thomas, HE Kay, TW Birnberg, NC Steinberg, GR Kemp, BE Oakhill, JS
2015 Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis
Biochem. J.
O’Brien, AJ Villani, LA Broadfield, LA Houde, VP Galic, S Blandino, G Kemp, BE Tsakiridis, T Muti, P Steinberg, GR
2016 Exercise reverses age-related vulnerability of the retina to injury by preventing complement-mediated synapse elimination via a BDNF-dependent pathway
Aging Cell
Chrysostomou, V Galic, S van Wijngaarden, P Trounce, IA Steinberg, GR Crowston, JG
2016 Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease
J. Neurosci.
Bayliss, JA Lemus, MB Stark, R Santos, VV Thompson, A Rees, DJ Galic, S Elsworth, JD Kemp, BE Davies, JS Andrews, ZB
2017 JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis, and Insulin Resistance in Obesity
Diabetes
Litwak, SA Pang, L Galic, S Igoillo-Esteve, M Stanley, WJ Turatsinze, JV Loh, K Thomas, HE Sharma, A Trepo, E Moreno, C Gough, DJ Eizirik, DL de Haan, JB Gurzov, EN
2017 AMPK beta 1 reduces tumor progression and improves survival in p53 null mice
Mol. Oncol.
Houde, VP Donzelli, S Sacconi, A Galic, S Hammill, JA Bramson, JL Foster, RA Tsakiridis, T Kemp, BE Grasso, G Blandino, G Muti, P Steinberg, GR
2017 The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs
Nat. Commun.
Dite, TA Ling, NXY Scott, JW Hoque, A Galic, S Parker, BL Ngoei, KRW Langendorf, CG O’Brien, MT Kundu, M Viollet, B Steinberg, GR Sakamoto, K Kemp, BE Oakhill, JS
2018 AMPK signaling to acetyl-CoA carboxylase is required for fasting- and cold-induced appetite but not thermogenesis
Elife
Galic, S Loh, K Murray-Segal, L Steinberg, GR Andrews, ZB Kemp, BE
2018 Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice
Cell Death Differ.
Wali, JA Galic, S Tan, CYR Gurzov, EN Frazier, AE Connor, T Ge, JJ Pappas, EG Stroud, D Varanasi, LC Selck, C Ryan, MT Thorburn, DR Kemp, BE Krishnamurthy, B Kay, TWH Thomas, HE
2018 Phosphorylation of Acetyl-CoA Carboxylase by AMPK Reduces Renal Fibrosis and Is Essential for the Anti-Fibrotic Effect of Metformin
J. Am. Soc. Nephrol.
Lee, M Katerelos, M Gleich, K Galic, S Kemp, BE Mount, PF Power, DA
2018 AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965
J. Biol. Chem.
Dite, TA Langendorf, CG Hoque, A Galic, S Rebello, RJ Ovens, AJ Lindqvist, LM Ngoei, KRW Ling, NXY Furic, L Kemp, BE Scott, JW Oakhill, JS
2019 Absence of the beta 1 subunit of AMP-activated protein kinase reduces myofibroblast infiltration of the kidneys in early diabetes
International Journal Of Experimental Pathology
Choy, SW Fraser, SA Katerelos, M Galic, S Kemp, BE Mount, PF Power, DA
2019 Allosteric regulation of AMP-activated protein kinase by adenylate nucleotides and small-molecule drugs
Biochemical Society Transactions
Matos, ALDA Oakhill, JS Moreira, J Loh, K Galic, S Scott, JW
2019 Inhibition of Adenosine Monophosphate-Activated Protein Kinase-3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Signaling Leads to Hypercholesterolemia and Promotes Hepatic Steatosis and Insulin Resistance
Hepatol. Commun.
Loh, K Tam, S Murray-Segal, L Huynh, K Meikle, PJ Scott, JW van Denderen, B Chen, ZP Steel, R LeBlond, ND Burkovsky, LA O’Dwyer, C Nunes, JRC Steinberg, GR Fullerton, MD Galic, S Kemp, BE
2019 ATP synthase inhibitory factor 1 (IF1), a novel myokine, regulates glucose metabolism by AMPK and Akt dual pathways
Faseb Journal
Lee, HJ Moon, J Chung, I Chung, JH Park, C Lee, JO Han, JA Kang, MJ Yoo, EH Kwak, SY Jo, G Park, W Park, J Kim, KM Lim, S Ngoei, KRW Ling, NXY Oakhill, JS Galic, S Murray-Segal, L Kemp, BE Mantzoros, CS Krauss, RM Shin, MJ Kim, HS
2020 Functional analysis of an R311C variant of Ca2+-calmodulin-dependent protein kinase kinase-2 (CaMKK2) found as a de novo mutation in a patient with bipolar disorder
Bipolar Disorders
Ling, NXY Langendorf, CG Hoque, A Galic, S Loh, K Kemp, BE Gundlach, AL Oakhill, JS Scott, JW
2020 Genetic loss of AMPK-glycogen binding destabilises AMPK and disrupts metabolism
Molecular Metabolism
Hoffman, NJ Whitfield, J Janzen, NR Belhaj, MR Galic, S Murray-Segal, L Smiles, WJ Ling, NXY Dite, TA Scott, JW Oakhill, JS Brink, R Kemp, BE Hawley, JA
2020 CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins
Journal Of Biological Chemistry
Langendorf, CG O’Brien, MT Ngoei, KRW McAloon, LM Dhagat, U Hoque, A Ling, NXY Dite, TA Galic, S Loh, K Parker, MW Oakhill, JS Kemp, BE Scott, JW
2020 Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK beta 1 isoforms
Nature Metabolism
Pinkosky, SL Scott, JW Desjardins, EM Smith, BK Day, EA Ford, RJ Langendorf, CG Ling, NXY Nero, TL Loh, K Galic, S Hoque, A Smiles, WJ Ngoei, KRW Parker, MW Yan, Y Melcher, K Kemp, BE Oakhill, JS Steinberg, GR
2020 The myokine meteorin-like (metrnl) improves glucose tolerance in both skeletal muscle cells and mice by targeting AMPK alpha 2
Febs Journal
Lee, JO Byun, WS Kang, MJ Han, JA Moon, J Shin, MJ Lee, HJ Chung, JH Lee, JS Son, CG Song, KH Kim, TW Lee, ES Kim, HM Chung, CH Ngoei, KRW Ling, NXY Oakhill, JS Galic, S Murray-Segal, L Kemp, BE Kim, KM Lim, S Kim, HS
2021 Regulation of Pancreatic beta-Cell Function by the NPY System
Endocrinology
Yang, CH Onda, DA Oakhill, JS Scott, JW Galic, S Loh, K
2021 Molecular Mechanisms Underlying the Beneficial Effects of Exercise on Brain Function and Neurological Disorders
International Journal Of Molecular Sciences
Nay, K Smiles, WJ Kaiser, J McAloon, LM Loh, K Galic, S Oakhill, JS Gundlach, AL Scott, JW
2022 Neuropeptide Y1 receptor antagonism protects beta-cells and improves glycemic control in type 2 diabetes
Molecular Metabolism
Yang, CH Ann-Onda, D Lin, XZ Fynch, S Nadarajah, S Pappas, EG Liu, X Scott, JW Oakhill, JS Galic, S Shi, YC Moreno-Asso, A Smith, C Loudovaris, T Levinger, I Eizirik, DL Laybutt, DR Herzog, H Thomas, HE Loh, K
2022 An AMPKa2-specific phospho-switch controls lysosomal targeting for activation
Cell Reports
Morrison, KR Smiles, WJ Ling, NXY Hoque, A Shea, G Ngoei, KRW Yu, DY Murray-Segal, L Scott, JW Galic, S Kemp, BE Petersen, J Oakhill, JS