Year | Title | Author(s) |
2012 |
Reduced Socs3 expression in adipose tissue protects female mice against obesity-induced insulin resistance
Diabetologia |
Palanivel, R Fullerton, MD Galic, S Honeyman, J Hewitt, KA Jorgensen, SB Steinberg, GR |
2012 |
Elevated Hypothalamic TCPTP in Obesity Contributes to Cellular Leptin Resistance (vol 14, pg 684, 2011)
Cell Metabolism |
Loh, K Fukushima, A Zhang, XM Galic, S Briggs, D Enriori, PJ Simonds, S Wiede, F Reichenbach, A Hauser, C Sims, NA Bence, KK Zhang, S Zhang, ZY Kahn, BB Neel, BG Andrews, ZB Cowley, MA Tiganis, T |
2013 |
Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin
Nature Medicine |
Fullerton, MD Galic, S Marcinko, K Sikkema, S Pulinilkunnil, T Chen, ZP O’Neill, HM Ford, RJ Palanivel, R O’Brien, M Hardie, DG Macaulay, SL Schertzer, JD Dyck, JRB van Denderen, B Kemp, BE Steinberg, GR |
2013 |
Deletion of Skeletal Muscle SOCS3 Prevents Insulin Resistance in Obesity
Diabetes |
Jorgensen, SB O’Neill, HM Sylow, L Honeyman, J Hewitt, KA Palanivel, R Fullerton, MD Oberg, L Balendran, A Galic, S van der Poel, C Trounce, IA Lynch, GS Schertzer, JD Steinberg, GR |
2014 |
Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity
Biochemical Journal |
Galic, S Sachithanandan, N Kay, TW Steinberg, GR |
2014 |
AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice
Diabetologia |
O’Neill, HM Lally, JS Galic, S Thomas, M Azizi, PD Fullerton, MD Smith, BK Pulinilkunnil, T Chen, ZP Samaan, MC Jorgensen, SB Dyck, JRB Holloway, GP Hawke, TJ van Denderen, B Kemp, BE Steinberg, GR |
2014 |
Novel mechanisms of Na+ retention in obesity: phosphorylation of NKCC2 and regulation of SPAK/OSR1 by AMPK
American Journal Of Physiology-renal Physiology |
Davies, M Fraser, SA Galic, S Choy, SW Katerelos, M Gleich, K Kemp, BE Mount, PF Power, DA |
2014 |
Small Molecule Drug A-769662 and AMP Synergistically Activate Naive AMPK Independent of Upstream Kinase Signaling
Chemistry & Biology |
Scott, JW Ling, NM Issa, SMA Dite, TA O’Brien, MT Chen, ZP Galic, S Langendorf, CG Steinberg, GR Kemp, BE Oakhill, JS |
2014 |
Activation of AMPK reduces the co-transporter activity of NKCC1
Molecular Membrane Biology |
Fraser, SA Davies, M Katerelos, M Gleich, K Choy, SW Steel, R Galic, S Mount, PF Kemp, BE Power, DA |
2015 |
Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release
Chem Biol |
Scott, JW Dite, TA Kay, TW Ling, NXY Thomas, HE Foitzik, R Weng, QP Kemp, BE Graham, KL Langendorf, CG Steinberg, GR Galic, S Issa, SMA Birnberg, NC Oakhill, JS |
2015 |
Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release
Chem. Biol. |
Scott, JW Galic, S Graham, KL Foitzik, R Ling, NXY Dite, TA Issa, SMA Langendorf, CG Weng, QP Thomas, HE Kay, TW Birnberg, NC Steinberg, GR Kemp, BE Oakhill, JS |
2015 |
Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis
Biochem. J. |
O’Brien, AJ Villani, LA Broadfield, LA Houde, VP Galic, S Blandino, G Kemp, BE Tsakiridis, T Muti, P Steinberg, GR |
2016 |
Exercise reverses age-related vulnerability of the retina to injury by preventing complement-mediated synapse elimination via a BDNF-dependent pathway
Aging Cell |
Chrysostomou, V Galic, S van Wijngaarden, P Trounce, IA Steinberg, GR Crowston, JG |
2016 |
Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease
J. Neurosci. |
Bayliss, JA Lemus, MB Stark, R Santos, VV Thompson, A Rees, DJ Galic, S Elsworth, JD Kemp, BE Davies, JS Andrews, ZB |
2017 |
JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis, and Insulin Resistance in Obesity
Diabetes |
Litwak, SA Pang, L Galic, S Igoillo-Esteve, M Stanley, WJ Turatsinze, JV Loh, K Thomas, HE Sharma, A Trepo, E Moreno, C Gough, DJ Eizirik, DL de Haan, JB Gurzov, EN |
2017 |
AMPK beta 1 reduces tumor progression and improves survival in p53 null mice
Mol. Oncol. |
Houde, VP Donzelli, S Sacconi, A Galic, S Hammill, JA Bramson, JL Foster, RA Tsakiridis, T Kemp, BE Grasso, G Blandino, G Muti, P Steinberg, GR |
2017 |
The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs
Nat. Commun. |
Dite, TA Ling, NXY Scott, JW Hoque, A Galic, S Parker, BL Ngoei, KRW Langendorf, CG O’Brien, MT Kundu, M Viollet, B Steinberg, GR Sakamoto, K Kemp, BE Oakhill, JS |
2018 |
AMPK signaling to acetyl-CoA carboxylase is required for fasting- and cold-induced appetite but not thermogenesis
Elife |
Galic, S Loh, K Murray-Segal, L Steinberg, GR Andrews, ZB Kemp, BE |
2018 |
Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice
Cell Death Differ. |
Wali, JA Galic, S Tan, CYR Gurzov, EN Frazier, AE Connor, T Ge, JJ Pappas, EG Stroud, D Varanasi, LC Selck, C Ryan, MT Thorburn, DR Kemp, BE Krishnamurthy, B Kay, TWH Thomas, HE |
2018 |
Phosphorylation of Acetyl-CoA Carboxylase by AMPK Reduces Renal Fibrosis and Is Essential for the Anti-Fibrotic Effect of Metformin
J. Am. Soc. Nephrol. |
Lee, M Katerelos, M Gleich, K Galic, S Kemp, BE Mount, PF Power, DA |
2018 |
AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965
J. Biol. Chem. |
Dite, TA Langendorf, CG Hoque, A Galic, S Rebello, RJ Ovens, AJ Lindqvist, LM Ngoei, KRW Ling, NXY Furic, L Kemp, BE Scott, JW Oakhill, JS |
2019 |
Absence of the beta 1 subunit of AMP-activated protein kinase reduces myofibroblast infiltration of the kidneys in early diabetes
International Journal Of Experimental Pathology |
Choy, SW Fraser, SA Katerelos, M Galic, S Kemp, BE Mount, PF Power, DA |
2019 |
Allosteric regulation of AMP-activated protein kinase by adenylate nucleotides and small-molecule drugs
Biochemical Society Transactions |
Matos, ALDA Oakhill, JS Moreira, J Loh, K Galic, S Scott, JW |
2019 |
Inhibition of Adenosine Monophosphate-Activated Protein Kinase-3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Signaling Leads to Hypercholesterolemia and Promotes Hepatic Steatosis and Insulin Resistance
Hepatol. Commun. |
Loh, K Tam, S Murray-Segal, L Huynh, K Meikle, PJ Scott, JW van Denderen, B Chen, ZP Steel, R LeBlond, ND Burkovsky, LA O’Dwyer, C Nunes, JRC Steinberg, GR Fullerton, MD Galic, S Kemp, BE |
2019 |
ATP synthase inhibitory factor 1 (IF1), a novel myokine, regulates glucose metabolism by AMPK and Akt dual pathways
Faseb Journal |
Lee, HJ Moon, J Chung, I Chung, JH Park, C Lee, JO Han, JA Kang, MJ Yoo, EH Kwak, SY Jo, G Park, W Park, J Kim, KM Lim, S Ngoei, KRW Ling, NXY Oakhill, JS Galic, S Murray-Segal, L Kemp, BE Mantzoros, CS Krauss, RM Shin, MJ Kim, HS |
2020 |
Functional analysis of an R311C variant of Ca2+-calmodulin-dependent protein kinase kinase-2 (CaMKK2) found as a de novo mutation in a patient with bipolar disorder
Bipolar Disorders |
Ling, NXY Langendorf, CG Hoque, A Galic, S Loh, K Kemp, BE Gundlach, AL Oakhill, JS Scott, JW |
2020 |
Genetic loss of AMPK-glycogen binding destabilises AMPK and disrupts metabolism
Molecular Metabolism |
Hoffman, NJ Whitfield, J Janzen, NR Belhaj, MR Galic, S Murray-Segal, L Smiles, WJ Ling, NXY Dite, TA Scott, JW Oakhill, JS Brink, R Kemp, BE Hawley, JA |
2020 |
CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins
Journal Of Biological Chemistry |
Langendorf, CG O’Brien, MT Ngoei, KRW McAloon, LM Dhagat, U Hoque, A Ling, NXY Dite, TA Galic, S Loh, K Parker, MW Oakhill, JS Kemp, BE Scott, JW |
2020 |
Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK beta 1 isoforms
Nature Metabolism |
Pinkosky, SL Scott, JW Desjardins, EM Smith, BK Day, EA Ford, RJ Langendorf, CG Ling, NXY Nero, TL Loh, K Galic, S Hoque, A Smiles, WJ Ngoei, KRW Parker, MW Yan, Y Melcher, K Kemp, BE Oakhill, JS Steinberg, GR |
2020 |
The myokine meteorin-like (metrnl) improves glucose tolerance in both skeletal muscle cells and mice by targeting AMPK alpha 2
Febs Journal |
Lee, JO Byun, WS Kang, MJ Han, JA Moon, J Shin, MJ Lee, HJ Chung, JH Lee, JS Son, CG Song, KH Kim, TW Lee, ES Kim, HM Chung, CH Ngoei, KRW Ling, NXY Oakhill, JS Galic, S Murray-Segal, L Kemp, BE Kim, KM Lim, S Kim, HS |
2021 |
Regulation of Pancreatic beta-Cell Function by the NPY System
Endocrinology |
Yang, CH Onda, DA Oakhill, JS Scott, JW Galic, S Loh, K |
2021 |
Molecular Mechanisms Underlying the Beneficial Effects of Exercise on Brain Function and Neurological Disorders
International Journal Of Molecular Sciences |
Nay, K Smiles, WJ Kaiser, J McAloon, LM Loh, K Galic, S Oakhill, JS Gundlach, AL Scott, JW |
2022 |
Neuropeptide Y1 receptor antagonism protects beta-cells and improves glycemic control in type 2 diabetes
Molecular Metabolism |
Yang, CH Ann-Onda, D Lin, XZ Fynch, S Nadarajah, S Pappas, EG Liu, X Scott, JW Oakhill, JS Galic, S Shi, YC Moreno-Asso, A Smith, C Loudovaris, T Levinger, I Eizirik, DL Laybutt, DR Herzog, H Thomas, HE Loh, K |
2022 |
An AMPKa2-specific phospho-switch controls lysosomal targeting for activation
Cell Reports |
Morrison, KR Smiles, WJ Ling, NXY Hoque, A Shea, G Ngoei, KRW Yu, DY Murray-Segal, L Scott, JW Galic, S Kemp, BE Petersen, J Oakhill, JS |