Publications by Researcher: Kay, TWH

YearTitleAuthor(s)
2012 Normalized NEFA Dynamics During an OGTT After Islet Transplantation
Vethakkan, SR Walters, JM Gooley, JL Boston, RC Kay, TWH Goodman, DJ Jenkins, AJ Ward, GM
2012 Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients
Coppieters, KT Dotta, F Amirian, N Campbell, PD Kay, TWH Atkinson, MA Roep, BO von Herrath, MG
2012 Intra-islet proliferation of cytotoxic T lymphocytes contributes to insulitis progression
Graham, KL Krishnamurthy, B Fynch, S Ayala-Perez, R Slattery, RM Santamaria, P Thomas, HE Kay, TWH
2012 Residual methylprednisolone suppresses human T-cell responses to spleen, but not islet, extracts from deceased organ donors
Joffe, M Necula, AS Chand, R McWhinney, BC Krishnamurthy, B Loudovaris, T Goodman, D Thomas, HE Kay, TWH Mannering, SI
2012 Complete Diabetes Protection Despite Delayed Thymic Tolerance in NOD8.3 TCR Transgenic Mice Due to Antigen-Induced Extrathymic Deletion of T Cells
Krishnamurthy, B Chee, J Jhala, G Fynch, S Graham, KL Santamaria, P Morahan, G Allison, J Izon, D Thomas, HE Kay, TWH
2012 Improvement in Outcomes of Clinical Islet Transplantation: 1999-2010
Barton, FB Rickels, MR Alejandro, R Hering, BJ Wease, S Naziruddin, B Oberholzer, J Odorico, JS Garfinkel, MR Levy, M Pattou, F Berney, T Secchi, A Messinger, S Senior, PA Maffi, P Posselt, A Stock, PG Kaufman, DB Luo, XR Kandeel, F Cagliero, E Turgeon, NA Witkowski, P Naji, A O’Connell, PJ Greenbaum, C Kudva, YC Brayman, KL Aull, MJ Larsen, C Kay, TWH Fernandez, LA Vantyghem, MC Bellin, M Shapiro, AMJ
2014 The Incretin Response After Successful Islet Transplantation
Vethakkan, SR Walters, JM Gooley, JL Boston, RC Kay, TWH Goodman, DJ Jenkins, AJ Ward, GM
2014 Functional cytotoxic T lymphocytes against IGRP(206-214) predict diabetes in the non-obese diabetic mouse
Ko, HJ Chee, J Sutherland, RM Thomas, HE Zhan, YF Krishnamurthy, B Kay, TWH Lew, AM
2014 Deficiency in Type I Interferon Signaling Prevents the Early Interferon-Induced Gene Signature in Pancreatic Islets but Not Type 1 Diabetes in NOD Mice
Quah, HS Miranda-Hernandez, S Khoo, A Harding, A Fynch, S Elkerbout, L Brodnicki, TC Baxter, AG Kay, TWH Thomas, HE Graham, KL
2014 The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity
Wali, JA Rondas, D McKenzie, MD Zhao, Y Elkerbout, L Fynch, S Gurzov, EN Akira, S Mathieu, C Kay, TWH Overbergh, L Strasser, A Thomas, HE
2014 Effector-Memory T Cells Develop in Islets and Report Islet Pathology in Type 1 Diabetes
Chee, J Ko, HJ Skowera, A Jhala, G Catterall, T Graham, KL Sutherland, RM Thomas, HE Lew, AM Peakman, M Kay, TWH Krishnamurthy, B
2015 Inactivation of Protein Tyrosine Phosphatases Enhances Interferon Signaling in Pancreatic Islets
Stanley, WJ Litwak, SA Quah, HS Tan, SM Kay, TWH Tiganis, T de Haan, JB Thomas, HE Gurzov, EN
2015 Lipotoxic Stress Induces Pancreatic beta-Cell Apoptosis through Modulation of Bcl-2 Proteins by the Ubiquitin-Proteasome System
Litwak, SA Wali, JA Pappas, EG Saadi, H Stanley, WJ Varanasi, LC Kay, TWH Thomas, HE Gurzov, EN
2015 Mouse pancreatic beta cells express MHC class II and stimulate CD4(+) T cells to proliferate
Zhao, YX Scott, NA Quah, HS Krishnamurthy, B Bond, F Loudovaris, T Mannering, SI Kay, TWH Thomas, HE
2015 A comparative analysis of high-throughput platforms for validation of a circulating microRNA signature in diabetic retinopathy
Farr, RJ Januszewski, AS Joglekar, MV Liang, H McAulley, AK Hewitt, AW Thomas, HE Loudovaris, T Kay, TWH Jenkins, A Hardikar, AA
2015 Autoreactive T cells induce necrosis and not BCL-2-regulated or death receptor-mediated apoptosis or RIPK3-dependent necroptosis of transplanted islets in a mouse model of type 1 diabetes
Zhao, YX Scott, NA Fynch, S Elkerbout, L Wong, WWL Mason, KD Strasser, A Huang, DC Kay, TWH Thomas, HE
2015 BIM Deficiency Protects NOD Mice From Diabetes by Diverting Thymocytes to Regulatory T Cells
Krishnamurthy, B Chee, J Jhala, G Trivedi, P Catterall, T Selck, C Gurzov, EN Brodnicki, TC Graham, KL Wali, JA Zhan, YF Gray, D Strasser, A Allison, J Thomas, HE Kay, TWH
2015 Proinsulin-Specific, HLA-DQ8, and HLA-DQ8-Transdimer-Restricted CD4(+) T Cells Infiltrate Islets in Type 1 Diabetes
Pathiraja, V Kuehlich, JP Campbell, PD Krishnamurthy, B Loudovaris, T Coates, PTH Brodnicki, TC O’Connell, PJ Kedzierska, K Rodda, C Bergman, P Hill, E Purcell, AW Dudek, NL Thomas, HE Kay, TWH Mannering, SI
2016 The case for an autoimmune aetiology of type 1 diabetes
Mannering, SI Pathiraja, V Kay, TWH