| Year | Title | Author(s) |
|---|
| 2015 |
Lipotoxic Stress Induces Pancreatic beta-Cell Apoptosis through Modulation of Bcl-2 Proteins by the Ubiquitin-Proteasome System
Journal Of Diabetes Research |
Litwak, SA Wali, JA Pappas, EG Saadi, H Stanley, WJ Varanasi, LC Kay, TWH Thomas, HE Gurzov, EN |
| 2016 |
The JAK/STAT pathway in obesity and diabetes
Febs J. |
Gurzov, EN Stanley, WJ Pappas, EG Thomas, HE Gough, DJ |
| 2016 |
p53-upregulated-modulator-of-apoptosis (PUMA) deficiency affects food intake but does not impact on body weight or glucose homeostasis in diet-induced obesity.
Sci Rep |
Litwak, SA Loh, K Stanley, WJ Pappas, EG Wali, JA Selck, C Strasser, A Thomas, HE Gurzov, EN |
| 2017 |
Granzyme A Deficiency Breaks Immune Tolerance and Promotes Autoimmune Diabetes Through a Type I Interferon-Dependent Pathway
Diabetes |
Mollah, ZUA Quah, HS Graham, KL Jhala, G Krishnamurthy, B Dharma, JFM Chee, J Trivedi, PM Pappas, EG Mackin, L Chu, EPF Akazawa, S Fynch, S Hodson, C Deans, AJ Trapani, JA Chong, MMW Bird, PI Brodnicki, TC Thomas, HE Kay, TWH |
| 2018 |
Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice
Cell Death Differ. |
Wali, JA Galic, S Tan, CYR Gurzov, EN Frazier, AE Connor, T Ge, JJ Pappas, EG Stroud, D Varanasi, LC Selck, C Ryan, MT Thorburn, DR Kemp, BE Krishnamurthy, B Kay, TWH Thomas, HE |
| 2019 |
Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans
Diabetologia |
Bensellam, M Shi, YC Chan, JY Laybutt, DR Chae, H Abou-Samra, M Pappas, EG Thomas, HE Gilon, P Jonas, JC |
| 2020 |
The JAK1 Selective Inhibitor ABT 317 Blocks Signaling Through Interferon-gamma and Common gamma Chain Cytokine Receptors to Reverse Autoimmune Diabetes in NOD Mice
Frontiers In Immunology |
Ge, TT Jhala, G Fynch, S Akazawa, S Litwak, S Pappas, EG Catterall, T Vakil, I Long, AJ Olson, LM Krishnamurthy, B Kay, TW Thomas, HE |
| 2021 |
Tolerance to Proinsulin-1 Reduces Autoimmune Diabetes in NOD Mice
Frontiers In Immunology |
Jhala, G Selck, C Chee, J Kwong, CTJ Pappas, EG Thomas, HE Kay, TWH Krishnamurthy, B |
| 2021 |
Deficiency of the innate immune adaptor STING promotes autoreactive T cell expansion in NOD mice
Diabetologia |
Akazawa, S Mackin, L Jhala, G Fynch, S Catterall, T Selck, C Graham, KL Krishnamurthy, B Pappas, EG Kwong, CTJ Sutherland, APR Kay, TWH Brodnicki, TC Thomas, HE |
| 2022 |
Neuropeptide Y1 receptor antagonism protects beta-cells and improves glycemic control in type 2 diabetes
Molecular Metabolism |
Yang, CH Ann-Onda, D Lin, XZ Fynch, S Nadarajah, S Pappas, EG Liu, X Scott, JW Oakhill, JS Galic, S Shi, YC Moreno-Asso, A Smith, C Loudovaris, T Levinger, I Eizirik, DL Laybutt, DR Herzog, H Thomas, HE Loh, K |