Publications by Researcher: Krishnamurthy, B

YearTitleAuthor(s)
2012 Complete Diabetes Protection Despite Delayed Thymic Tolerance in NOD8.3 TCR Transgenic Mice Due to Antigen-Induced Extrathymic Deletion of T Cells
Diabetes
Krishnamurthy, B Chee, J Jhala, G Fynch, S Graham, KL Santamaria, P Morahan, G Allison, J Izon, D Thomas, HE Kay, TWH
2012 Intra-islet proliferation of cytotoxic T lymphocytes contributes to insulitis progression
European Journal Of Immunology
Graham, KL Krishnamurthy, B Fynch, S Ayala-Perez, R Slattery, RM Santamaria, P Thomas, HE Kay, TWH
2012 Granzyme B Is Dispensable in the Development of Diabetes in Non-Obese Diabetic Mice
Plos One
Mollah, ZU Graham, KL Krishnamurthy, B Trivedi, P Brodnicki, TC Trapani, JA Kay, TW Thomas, HE
2012 Residual methylprednisolone suppresses human T-cell responses to spleen, but not islet, extracts from deceased organ donors
International Immunology
Joffe, M Necula, AS Chand, R McWhinney, BC Krishnamurthy, B Loudovaris, T Goodman, D Thomas, HE Kay, TWH Mannering, SI
2013 Proinflammatory cytokines contribute to development and function of regulatory T cells in type 1 diabetes
Translational Immunology In Asia-oceania
Thomas, HE Graham, KL Chee, J Thomas, R Kay, TW Krishnamurthy, B
2014 Functional cytotoxic T lymphocytes against IGRP(206-214) predict diabetes in the non-obese diabetic mouse
Immunology And Cell Biology
Ko, HJ Chee, J Sutherland, RM Thomas, HE Zhan, YF Krishnamurthy, B Kay, TWH Lew, AM
2014 Effector-Memory T Cells Develop in Islets and Report Islet Pathology in Type 1 Diabetes
Journal Of Immunology
Chee, J Ko, HJ Skowera, A Jhala, G Catterall, T Graham, KL Sutherland, RM Thomas, HE Lew, AM Peakman, M Kay, TWH Krishnamurthy, B
2015 BIM Deficiency Protects NOD Mice From Diabetes by Diverting Thymocytes to Regulatory T Cells
Diabetes
Krishnamurthy, B Chee, J Jhala, G Trivedi, P Catterall, T Selck, C Gurzov, EN Brodnicki, TC Graham, KL Wali, JA Zhan, YF Gray, D Strasser, A Allison, J Thomas, HE Kay, TWH
2015 Mouse pancreatic beta cells express MHC class II and stimulate CD4(+) T cells to proliferate
Eur. J. Immunol.
Zhao, YX Scott, NA Quah, HS Krishnamurthy, B Bond, F Loudovaris, T Mannering, SI Kay, TWH Thomas, HE
2015 Proinsulin-Specific, HLA-DQ8, and HLA-DQ8-Transdimer-Restricted CD4(+) T Cells Infiltrate Islets in Type 1 Diabetes
Diabetes
Pathiraja, V Kuehlich, JP Campbell, PD Krishnamurthy, B Loudovaris, T Coates, PTH Brodnicki, TC O’Connell, PJ Kedzierska, K Rodda, C Bergman, P Hill, E Purcell, AW Dudek, NL Thomas, HE Kay, TWH Mannering, SI
2016 Perforin facilitates beta cell killing and regulates autoreactive CD8+ T cell responses to antigen in mouse models of type 1 dia
Immunol Cell Biol
Graham, KL Trivedi, P Kay, TW Slattery, RM Fynch, S Krishnamurthy, B Thomas, HE
2016 Analysis of antigen specific T cells in diabetes - Lessons from pre-clinical studies and early clinical trials
J. Autoimmun.
Krishnamurthy, B Selck, C Chee, J Jhala, G Kay, TWH
2016 Perinatal tolerance to proinsulin is sufficient to prevent autoimmune diabetes
Jci Insight
Jhala, G Chee, J Trivedi, PM Selck, C Gurzov, EN Graham, KL Thomas, HE Kay, TWH Krishnamurthy, B
2017 Granzyme A Deficiency Breaks Immune Tolerance and Promotes Autoimmune Diabetes Through a Type I Interferon-Dependent Pathway
Diabetes
Mollah, ZUA Quah, HS Graham, KL Jhala, G Krishnamurthy, B Dharma, JFM Chee, J Trivedi, PM Pappas, EG Mackin, L Chu, EPF Akazawa, S Fynch, S Hodson, C Deans, AJ Trapani, JA Chong, MMW Bird, PI Brodnicki, TC Thomas, HE Kay, TWH
2017 Repurposed JAK1/JAK2 Inhibitor Reverses Established Autoimmune Insulitis in NOD Mice
Diabetes
Trivedi, PM Graham, KL Scott, NA Jenkins, MR Majaw, S Sutherland, RM Fynch, S Lew, AM Burns, CJ Krishnamurthy, B Brodnicki, TC Mannering, SI Kay, TW Thomas, HE
2017 Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes
Nat. Immunol.
Marino, E Richards, JL McLeod, KH Stanley, D Yap, YA Knight, J McKenzie, C Kranich, J Oliveira, AC Rossello, FJ Krishnamurthy, B Nefzger, CM Macia, L Thorburn, A Baxter, AG Morahan, G Wong, LH Polo, JM Moore, RJ Lockett, TJ Clarke, JM Topping, DL Harrison, LC Mackay, CR
2018 IFN gamma-Induced MHC Class II Expression on Islet Endothelial Cells Is an Early Marker of Insulitis but Is Not Required for Diabetogenic CD4(+) T Cell Migration
Front. Immunol.
Scott, NA Zhao, YX Krishnamurthy, B Mannering, SI Kay, TWH Thomas, HE
2018 NF-kappa B is weakly activated in the NOD mouse model of type 1 diabetes
Sci Rep
Irvin, AE Jhala, G Zhao, YX Blackwell, TS Krishnamurthy, B Thomas, HE Kay, TWH
2018 Proinsulin C-peptide is an autoantigen in people with type 1 diabetes
Proc. Natl. Acad. Sci. U. S. A.
So, M Elso, CM Tresoldi, E Pakusch, M Pathiraja, V Wentworth, JM Harrison, LC Krishnamurthy, B Thomas, HE Rodda, C Cameron, FJ McMahon, J Kay, TWH Mannering, SI
2018 Diabetes associated with immune checkpoint inhibition: presentation and management challenges
Diabetic Med.
Galligan, A Xu, W Fourlanos, S Nankervis, A Chiang, C Mant, AM Parente, P Rischin, D Krishnamurthy, B Sandhu, S Colman, PG
2018 Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice
Cell Death Differ.
Wali, JA Galic, S Tan, CYR Gurzov, EN Frazier, AE Connor, T Ge, JJ Pappas, EG Stroud, D Varanasi, LC Selck, C Ryan, MT Thorburn, DR Kemp, BE Krishnamurthy, B Kay, TWH Thomas, HE