Publications by Researcher: Krishnamurthy, B

Year	Title	Author(s)
2012	Complete Diabetes Protection Despite Delayed Thymic Tolerance in NOD8.3 TCR Transgenic Mice Due to Antigen-Induced Extrathymic Deletion of T Cells Diabetes	Krishnamurthy, B Chee, J Jhala, G Fynch, S Graham, KL Santamaria, P Morahan, G Allison, J Izon, D Thomas, HE Kay, TWH
2012	Intra-islet proliferation of cytotoxic T lymphocytes contributes to insulitis progression European Journal Of Immunology	Graham, KL Krishnamurthy, B Fynch, S Ayala-Perez, R Slattery, RM Santamaria, P Thomas, HE Kay, TWH
2012	Granzyme B Is Dispensable in the Development of Diabetes in Non-Obese Diabetic Mice Plos One	Mollah, ZU Graham, KL Krishnamurthy, B Trivedi, P Brodnicki, TC Trapani, JA Kay, TW Thomas, HE
2012	Residual methylprednisolone suppresses human T-cell responses to spleen, but not islet, extracts from deceased organ donors International Immunology	Joffe, M Necula, AS Chand, R McWhinney, BC Krishnamurthy, B Loudovaris, T Goodman, D Thomas, HE Kay, TWH Mannering, SI
2013	Proinflammatory cytokines contribute to development and function of regulatory T cells in type 1 diabetes Translational Immunology In Asia-oceania	Thomas, HE Graham, KL Chee, J Thomas, R Kay, TW Krishnamurthy, B
2014	Functional cytotoxic T lymphocytes against IGRP(206-214) predict diabetes in the non-obese diabetic mouse Immunology And Cell Biology	Ko, HJ Chee, J Sutherland, RM Thomas, HE Zhan, YF Krishnamurthy, B Kay, TWH Lew, AM
2014	Effector-Memory T Cells Develop in Islets and Report Islet Pathology in Type 1 Diabetes Journal Of Immunology	Chee, J Ko, HJ Skowera, A Jhala, G Catterall, T Graham, KL Sutherland, RM Thomas, HE Lew, AM Peakman, M Kay, TWH Krishnamurthy, B
2015	BIM Deficiency Protects NOD Mice From Diabetes by Diverting Thymocytes to Regulatory T Cells Diabetes	Krishnamurthy, B Chee, J Jhala, G Trivedi, P Catterall, T Selck, C Gurzov, EN Brodnicki, TC Graham, KL Wali, JA Zhan, YF Gray, D Strasser, A Allison, J Thomas, HE Kay, TWH
2015	Mouse pancreatic beta cells express MHC class II and stimulate CD4(+) T cells to proliferate Eur. J. Immunol.	Zhao, YX Scott, NA Quah, HS Krishnamurthy, B Bond, F Loudovaris, T Mannering, SI Kay, TWH Thomas, HE
2015	Proinsulin-Specific, HLA-DQ8, and HLA-DQ8-Transdimer-Restricted CD4(+) T Cells Infiltrate Islets in Type 1 Diabetes Diabetes	Pathiraja, V Kuehlich, JP Campbell, PD Krishnamurthy, B Loudovaris, T Coates, PTH Brodnicki, TC O’Connell, PJ Kedzierska, K Rodda, C Bergman, P Hill, E Purcell, AW Dudek, NL Thomas, HE Kay, TWH Mannering, SI
2016	Perforin facilitates beta cell killing and regulates autoreactive CD8+ T cell responses to antigen in mouse models of type 1 dia Immunol Cell Biol	Graham, KL Trivedi, P Kay, TW Slattery, RM Fynch, S Krishnamurthy, B Thomas, HE
2016	Analysis of antigen specific T cells in diabetes - Lessons from pre-clinical studies and early clinical trials J. Autoimmun.	Krishnamurthy, B Selck, C Chee, J Jhala, G Kay, TWH
2016	Perinatal tolerance to proinsulin is sufficient to prevent autoimmune diabetes Jci Insight	Jhala, G Chee, J Trivedi, PM Selck, C Gurzov, EN Graham, KL Thomas, HE Kay, TWH Krishnamurthy, B
2017	Granzyme A Deficiency Breaks Immune Tolerance and Promotes Autoimmune Diabetes Through a Type I Interferon-Dependent Pathway Diabetes	Mollah, ZUA Quah, HS Graham, KL Jhala, G Krishnamurthy, B Dharma, JFM Chee, J Trivedi, PM Pappas, EG Mackin, L Chu, EPF Akazawa, S Fynch, S Hodson, C Deans, AJ Trapani, JA Chong, MMW Bird, PI Brodnicki, TC Thomas, HE Kay, TWH
2017	Repurposed JAK1/JAK2 Inhibitor Reverses Established Autoimmune Insulitis in NOD Mice Diabetes	Trivedi, PM Graham, KL Scott, NA Jenkins, MR Majaw, S Sutherland, RM Fynch, S Lew, AM Burns, CJ Krishnamurthy, B Brodnicki, TC Mannering, SI Kay, TW Thomas, HE
2017	Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes Nat. Immunol.	Marino, E Richards, JL McLeod, KH Stanley, D Yap, YA Knight, J McKenzie, C Kranich, J Oliveira, AC Rossello, FJ Krishnamurthy, B Nefzger, CM Macia, L Thorburn, A Baxter, AG Morahan, G Wong, LH Polo, JM Moore, RJ Lockett, TJ Clarke, JM Topping, DL Harrison, LC Mackay, CR
2018	IFN gamma-Induced MHC Class II Expression on Islet Endothelial Cells Is an Early Marker of Insulitis but Is Not Required for Diabetogenic CD4(+) T Cell Migration Front. Immunol.	Scott, NA Zhao, YX Krishnamurthy, B Mannering, SI Kay, TWH Thomas, HE
2018	NF-kappa B is weakly activated in the NOD mouse model of type 1 diabetes Sci Rep	Irvin, AE Jhala, G Zhao, YX Blackwell, TS Krishnamurthy, B Thomas, HE Kay, TWH
2018	Proinsulin C-peptide is an autoantigen in people with type 1 diabetes Proc. Natl. Acad. Sci. U. S. A.	So, M Elso, CM Tresoldi, E Pakusch, M Pathiraja, V Wentworth, JM Harrison, LC Krishnamurthy, B Thomas, HE Rodda, C Cameron, FJ McMahon, J Kay, TWH Mannering, SI
2018	Diabetes associated with immune checkpoint inhibition: presentation and management challenges Diabetic Med.	Galligan, A Xu, W Fourlanos, S Nankervis, A Chiang, C Mant, AM Parente, P Rischin, D Krishnamurthy, B Sandhu, S Colman, PG
2018	Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice Cell Death Differ.	Wali, JA Galic, S Tan, CYR Gurzov, EN Frazier, AE Connor, T Ge, JJ Pappas, EG Stroud, D Varanasi, LC Selck, C Ryan, MT Thorburn, DR Kemp, BE Krishnamurthy, B Kay, TWH Thomas, HE
2019	Soluble FAS ligand is not required for pancreatic islet inflammation or beta-cell destruction in non-obese diabetic mice Cell Death Discovery	Trivedi, PM Fynch, S Kennedy, LM Chee, J Krishnamurthy, B O’Reilly, LA Strasser, A Kay, TWH Thomas, HE
2019	Subclinical hypothyroidism during pregnancy: the Melbourne public hospitals consensus Internal Medicine Journal	Hamblin, PS Sheehan, PM Allan, C Houlihan, CA Lu, ZX Forehan, SP Topliss, DJ Gilfillan, C Krishnamurthy, B Renouf, D Sztal-Mazer, S Varadarajan, S
2020	Comment on Trinh et al. Successful Treatment of Immune Checkpoint Inhibitor-Induced Diabetes With Infliximab. Diabetes Care 2019;42:e153-e154 Diabetes Care	Galligan, A Krishnamurthy, B Kay, TW
2020	The JAK1 Selective Inhibitor ABT 317 Blocks Signaling Through Interferon-gamma and Common gamma Chain Cytokine Receptors to Reverse Autoimmune Diabetes in NOD Mice Frontiers In Immunology	Ge, TT Jhala, G Fynch, S Akazawa, S Litwak, S Pappas, EG Catterall, T Vakil, I Long, AJ Olson, LM Krishnamurthy, B Kay, TW Thomas, HE
2021	Reducing adverse events associated with the glucagon stimulation test for the assessment of growth hormone deficiency in adults with a high prevalence of pituitary hormone deficiencies Clinical Endocrinology	Gogna, R Jung, C McLachlan, K Krishnamurthy, B Hong, A Derbyshire, M Kiburg, KV Zacharin, M MacIsaac, RJ Sachithanandan, N Caputo, C
2021	Severe acute respiratory syndrome coronavirus 2 as a potential cause of type 1 diabetes facilitated by spike protein receptor binding domain attachment to human islet cells: An illustrative case study and experimental data Diabetic Medicine	Venkatesh, N Astbury, N Thomas, MC Rosado, CJ Pappas, E Krishnamurthy, B MacIsaac, RJ Kay, TWH Thomas, HE O’Neal, DN
2021	Tolerance to Proinsulin-1 Reduces Autoimmune Diabetes in NOD Mice Frontiers In Immunology	Jhala, G Selck, C Chee, J Kwong, CTJ Pappas, EG Thomas, HE Kay, TWH Krishnamurthy, B
2021	Deficiency of the innate immune adaptor STING promotes autoreactive T cell expansion in NOD mice Diabetologia	Akazawa, S Mackin, L Jhala, G Fynch, S Catterall, T Selck, C Graham, KL Krishnamurthy, B Pappas, EG Kwong, CTJ Sutherland, APR Kay, TWH Brodnicki, TC Thomas, HE
2021	Harnessing CD8(+) T-cell exhaustion to treat type 1 diabetes Immunology And Cell Biology	Kwong, CTJ Selck, C Tahija, K McAnaney, LJ Le, DV Kay, TWH Thomas, HE Krishnamurthy, B
2022	Case Report: Hypoglycemia Due to a Novel Activating Glucokinase Variant in an Adult - a Molecular Approach Frontiers In Endocrinology	Koneshamoorthy, A Seniveratne-Epa, D Calder, G Sawyer, M Kay, TWH Farrell, S Loudovaris, T Mariana, L McCarthy, D Lyu, RQ Liu, X Thorn, P Tong, JS Chin, LK Zacharin, M Trainer, A Taylor, S MacIsaac, RJ Sachithanandan, N Thomas, HE Krishnamurthy, B