Publications by Researcher: Gurzov, EN

YearTitleAuthor(s)
2014 Activation of the NLRP3 Inflammasome Complex is Not Required for Stress-Induced Death of Pancreatic Islets
Plos One
Wali, JA Gurzov, EN Fynch, S Elkerbout, L Kay, TW Masters, SL Thomas, HE
2014 The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity
Cell Death & Disease
Wali, JA Rondas, D McKenzie, MD Zhao, Y Elkerbout, L Fynch, S Gurzov, EN Akira, S Mathieu, C Kay, TWH Overbergh, L Strasser, A Thomas, HE
2015 Protein tyrosine phosphatases: molecular switches in metabolism and diabetes
Trends In Endocrinology And Metabolism
Gurzov, EN Stanley, WJ Brodnicki, TC Thomas, HE
2015 BIM Deficiency Protects NOD Mice From Diabetes by Diverting Thymocytes to Regulatory T Cells
Diabetes
Krishnamurthy, B Chee, J Jhala, G Trivedi, P Catterall, T Selck, C Gurzov, EN Brodnicki, TC Graham, KL Wali, JA Zhan, YF Gray, D Strasser, A Allison, J Thomas, HE Kay, TWH
2015 Inactivation of Protein Tyrosine Phosphatases Enhances Interferon Signaling in Pancreatic Islets
Diabetes
Stanley, WJ Litwak, SA Quah, HS Tan, SM Kay, TWH Tiganis, T de Haan, JB Thomas, HE Gurzov, EN
2015 Lipotoxic Stress Induces Pancreatic beta-Cell Apoptosis through Modulation of Bcl-2 Proteins by the Ubiquitin-Proteasome System
Journal Of Diabetes Research
Litwak, SA Wali, JA Pappas, EG Saadi, H Stanley, WJ Varanasi, LC Kay, TWH Thomas, HE Gurzov, EN
2016 The JAK/STAT pathway in obesity and diabetes
Febs J.
Gurzov, EN Stanley, WJ Pappas, EG Thomas, HE Gough, DJ
2016 Inhibition of hIAPP Amyloid Aggregation and Pancreatic beta-Cell Toxicity by OH-Terminated PAMAM Dendrimer
Small
Gurzov, EN Wang, B Pilkington, EH Chen, PY Kakinen, A Stanley, WJ Litwak, SA Hanssen, EG Davis, TP Ding, F Ke, PC
2016 Graphene oxide inhibits hIAPP amyloid fibrillation and toxicity in insulin-producing NIT-1 cells
Phys. Chem. Chem. Phys.
Nedumpully-Govindan, P Gurzov, EN Chen, PY Pilkington, EH Stanley, WJ Litwak, SA Davis, TP Ke, PC Ding, F
2016 Pancreatic beta-Cell Membrane Fluidity and Toxicity Induced by Human Islet Amyloid Polypeptide Species
Sci Rep
Pilkington, EH Gurzov, EN Kakinen, A Litwak, SA Stanley, WJ Davis, TP Ke, PC
2016 Perinatal tolerance to proinsulin is sufficient to prevent autoimmune diabetes
Jci Insight
Jhala, G Chee, J Trivedi, PM Selck, C Gurzov, EN Graham, KL Thomas, HE Kay, TWH Krishnamurthy, B
2016 p53-upregulated-modulator-of-apoptosis (PUMA) deficiency affects food intake but does not impact on body weight or glucose homeostasis in diet-induced obesity.
Sci Rep
Litwak, SA Loh, K Stanley, WJ Pappas, EG Wali, JA Selck, C Strasser, A Thomas, HE Gurzov, EN
2017 Zinc-coordination and C-peptide complexation: a potential mechanism for the endogenous inhibition of IAPP aggregation
Chem. Commun.
Ge, XW Kakinen, A Gurzov, EN Yang, W Pang, L Pilkington, EH Govindan-Nedumpully, P Chen, PY Separovic, F Davis, TP Ke, PC Ding, F
2017 Differential regulation of pro-inflammatory cytokine signalling by protein tyrosine phosphatases in pancreatic beta-cells
J. Mol. Endocrinol.
Stanley, WJ Trivedi, PM Sutherland, AP Thomas, HE Gurzov, EN
2017 Star Polymers Reduce Islet Amyloid Polypeptide Toxicity via Accelerated Amyloid Aggregation
Biomacromolecules
Pilkington, EH Lai, M Ge, XW Stanley, WJ Wang, B Wang, MY Kakinen, A Sani, MA Whittaker, MR Gurzov, EN Ding, F Quinn, JF Davis, TP Ke, PC
2017 Inhibition of Y1 receptor signaling improves islet transplant outcome
Nat. Commun.
Loh, K Shi, YC Walters, S Bensellam, M Lee, K Dezaki, K Nakata, M Ip, CK Chan, JY Gurzov, EN Thomas, HE Waibel, M Cantley, J Kay, TW Yada, T Laybutt, DR Grey, ST Herzog, H
2017 JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis, and Insulin Resistance in Obesity
Diabetes
Litwak, SA Pang, L Galic, S Igoillo-Esteve, M Stanley, WJ Turatsinze, JV Loh, K Thomas, HE Sharma, A Trepo, E Moreno, C Gough, DJ Eizirik, DL de Haan, JB Gurzov, EN
2018 Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice
Cell Death Differ.
Wali, JA Galic, S Tan, CYR Gurzov, EN Frazier, AE Connor, T Ge, JJ Pappas, EG Stroud, D Varanasi, LC Selck, C Ryan, MT Thorburn, DR Kemp, BE Krishnamurthy, B Kay, TWH Thomas, HE