Publications by Researcher: Gurzov, EN

Year	Title	Author(s)
2014	Activation of the NLRP3 Inflammasome Complex is Not Required for Stress-Induced Death of Pancreatic Islets Plos One	Wali, JA Gurzov, EN Fynch, S Elkerbout, L Kay, TW Masters, SL Thomas, HE
2014	The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity Cell Death & Disease	Wali, JA Rondas, D McKenzie, MD Zhao, Y Elkerbout, L Fynch, S Gurzov, EN Akira, S Mathieu, C Kay, TWH Overbergh, L Strasser, A Thomas, HE
2015	Protein tyrosine phosphatases: molecular switches in metabolism and diabetes Trends In Endocrinology And Metabolism	Gurzov, EN Stanley, WJ Brodnicki, TC Thomas, HE
2015	BIM Deficiency Protects NOD Mice From Diabetes by Diverting Thymocytes to Regulatory T Cells Diabetes	Krishnamurthy, B Chee, J Jhala, G Trivedi, P Catterall, T Selck, C Gurzov, EN Brodnicki, TC Graham, KL Wali, JA Zhan, YF Gray, D Strasser, A Allison, J Thomas, HE Kay, TWH
2015	Inactivation of Protein Tyrosine Phosphatases Enhances Interferon Signaling in Pancreatic Islets Diabetes	Stanley, WJ Litwak, SA Quah, HS Tan, SM Kay, TWH Tiganis, T de Haan, JB Thomas, HE Gurzov, EN
2015	Lipotoxic Stress Induces Pancreatic beta-Cell Apoptosis through Modulation of Bcl-2 Proteins by the Ubiquitin-Proteasome System Journal Of Diabetes Research	Litwak, SA Wali, JA Pappas, EG Saadi, H Stanley, WJ Varanasi, LC Kay, TWH Thomas, HE Gurzov, EN
2016	The JAK/STAT pathway in obesity and diabetes Febs J.	Gurzov, EN Stanley, WJ Pappas, EG Thomas, HE Gough, DJ
2016	Inhibition of hIAPP Amyloid Aggregation and Pancreatic beta-Cell Toxicity by OH-Terminated PAMAM Dendrimer Small	Gurzov, EN Wang, B Pilkington, EH Chen, PY Kakinen, A Stanley, WJ Litwak, SA Hanssen, EG Davis, TP Ding, F Ke, PC
2016	Pancreatic beta-Cell Membrane Fluidity and Toxicity Induced by Human Islet Amyloid Polypeptide Species Sci Rep	Pilkington, EH Gurzov, EN Kakinen, A Litwak, SA Stanley, WJ Davis, TP Ke, PC
2016	Graphene oxide inhibits hIAPP amyloid fibrillation and toxicity in insulin-producing NIT-1 cells Phys. Chem. Chem. Phys.	Nedumpully-Govindan, P Gurzov, EN Chen, PY Pilkington, EH Stanley, WJ Litwak, SA Davis, TP Ke, PC Ding, F
2016	Perinatal tolerance to proinsulin is sufficient to prevent autoimmune diabetes Jci Insight	Jhala, G Chee, J Trivedi, PM Selck, C Gurzov, EN Graham, KL Thomas, HE Kay, TWH Krishnamurthy, B
2016	p53-upregulated-modulator-of-apoptosis (PUMA) deficiency affects food intake but does not impact on body weight or glucose homeostasis in diet-induced obesity. Sci Rep	Litwak, SA Loh, K Stanley, WJ Pappas, EG Wali, JA Selck, C Strasser, A Thomas, HE Gurzov, EN
2017	Zinc-coordination and C-peptide complexation: a potential mechanism for the endogenous inhibition of IAPP aggregation Chem. Commun.	Ge, XW Kakinen, A Gurzov, EN Yang, W Pang, L Pilkington, EH Govindan-Nedumpully, P Chen, PY Separovic, F Davis, TP Ke, PC Ding, F
2017	Differential regulation of pro-inflammatory cytokine signalling by protein tyrosine phosphatases in pancreatic beta-cells J. Mol. Endocrinol.	Stanley, WJ Trivedi, PM Sutherland, AP Thomas, HE Gurzov, EN
2017	Star Polymers Reduce Islet Amyloid Polypeptide Toxicity via Accelerated Amyloid Aggregation Biomacromolecules	Pilkington, EH Lai, M Ge, XW Stanley, WJ Wang, B Wang, MY Kakinen, A Sani, MA Whittaker, MR Gurzov, EN Ding, F Quinn, JF Davis, TP Ke, PC
2017	Inhibition of Y1 receptor signaling improves islet transplant outcome Nat. Commun.	Loh, K Shi, YC Walters, S Bensellam, M Lee, K Dezaki, K Nakata, M Ip, CK Chan, JY Gurzov, EN Thomas, HE Waibel, M Cantley, J Kay, TW Yada, T Laybutt, DR Grey, ST Herzog, H
2017	JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis, and Insulin Resistance in Obesity Diabetes	Litwak, SA Pang, L Galic, S Igoillo-Esteve, M Stanley, WJ Turatsinze, JV Loh, K Thomas, HE Sharma, A Trepo, E Moreno, C Gough, DJ Eizirik, DL de Haan, JB Gurzov, EN
2018	Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice Cell Death Differ.	Wali, JA Galic, S Tan, CYR Gurzov, EN Frazier, AE Connor, T Ge, JJ Pappas, EG Stroud, D Varanasi, LC Selck, C Ryan, MT Thorburn, DR Kemp, BE Krishnamurthy, B Kay, TWH Thomas, HE
2020	Mitochondrial STAT3 contributes to pancreatic beta cell adaptation in obesity Diabetologia	Schaschkow, A Pang, L Litwak, SA Maillard, E Paula, FMM Eizirik, DL Marchetti, P Gough, DJ Gurzov, EN
2021	Insulin-Binding Peptide Probes Provide a Novel Strategy for Pancreatic beta-Cell Imaging Molecular Pharmaceutics	Eriksson, M Litwak, SA Yun, Y Stanley, WJ Thorn, P Ahlgren, U Gurzov, EN
2021	STAT3 Regulates Mitochondrial Gene Expression in Pancreatic beta-Cells and Its Deficiency Induces Glucose Intolerance in Obesity Diabetes	Schaschkow, A Pang, L Vandenbempt, V Elvira, B Litwak, SA Vekeriotaite, B Maillard, E Vermeersch, M Paula, FMM Pinget, M Perez-Morga, D Gough, DJ Gurzov, EN