| Year | Title | Author(s) |
|---|
| 2012 |
Granzyme B Is Dispensable in the Development of Diabetes in Non-Obese Diabetic Mice
Plos One |
Mollah, ZU Graham, KL Krishnamurthy, B Trivedi, P Brodnicki, TC Trapani, JA Kay, TW Thomas, HE |
| 2012 |
An indirect role for NK cells in a CD4(+) T-cell-dependent mouse model of type I diabetes
Immunology And Cell Biology |
Angstetra, E Graham, KL Zhao, YX Irvin, AE Elkerbout, L Santamaria, P Slattery, RM Kay, TW Thomas, HE |
| 2012 |
Expression of Pro- and Antiapoptotic Molecules of the Bcl-2 Family in Human Islets Postisolation
Cell Transplantation |
Campbell, PD Weinberg, A Chee, J Mariana, L Ayala, R Hawthorne, WJ O’Connell, PJ Loudovaris, T Cowley, MJ Kay, TW Grey, ST Thomas, HE |
| 2013 |
Proinflammatory cytokines contribute to development and function of regulatory T cells in type 1 diabetes
Translational Immunology In Asia-oceania |
Thomas, HE Graham, KL Chee, J Thomas, R Kay, TW Krishnamurthy, B |
| 2013 |
Hypoxia-Inducible Factor-la (HIF-l alpha) Potentiates beta-Cell Survival After Islet Transplantation of Human and Mouse Islets
Cell Transplantation |
Stokes, RA Cheng, K Deters, N Lau, SM Hawthorne, WJ O’Connell, PJ Stolp, J Grey, S Loudovaris, T Kay, TW Thomas, HE Gonzalez, FJ Gunton, JE |
| 2013 |
Multicenter Australian Trial of Islet Transplantation: Improving Accessibility and Outcomes
American Journal Of Transplantation |
O’Connell, PJ Holmes-Walker, DJ Goodman, D Hawthorne, WJ Loudovaris, T Gunton, JE Thomas, HE Grey, ST Drogemuller, CJ Ward, GM Torpy, DJ Coates, PT Kay, TW |
| 2014 |
Glycaemic control in diabetes is restored by therapeutic manipulation of cytokines that regulated beta cell stress
Nat Med |
Wang, R Whitehead, JP Borg, DJ Das, I Thomas, HE Hasnain, SZ Ng, CP Kay, TW Sheng, YH Loudovaris, T Prins, JB Tong, H Chen, AC Forbes, JM Harbourt, BE McGuckin, MA |
| 2014 |
Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity
Biochemical Journal |
Galic, S Sachithanandan, N Kay, TW Steinberg, GR |
| 2014 |
Activation of the NLRP3 Inflammasome Complex is Not Required for Stress-Induced Death of Pancreatic Islets
Plos One |
Wali, JA Gurzov, EN Fynch, S Elkerbout, L Kay, TW Masters, SL Thomas, HE |
| 2015 |
Localisation of dipeptidyl peptidase-4 (CD26) to human pancreatic ducts and islet alpha cells
Diabetes Res Clin Pract. |
Naselli, G Rogers, K Augstein, P Bandala-Sanchez, E Campbell, P Kay, TW Hawthorne, WJ Thomas, HE Loudovaris, T Heinke, P Harrison, LC |
| 2015 |
Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release
Chem Biol |
Langendorf, CG Steinberg, GR Galic, S Issa, SMA Birnberg, NC Scott, JW Dite, TA Kay, TW Ling, NXY Thomas, HE Foitzik, R Weng, QP Kemp, BE Graham, KL Oakhill, JS |
| 2015 |
Evidence-Informed Clinical Practice Recommendations for Treatment of Type 1 Diabetes Complicated by Problematic Hypoglycemia
Diabetes Care |
Choudhary, P Rickels, MR Senior, PA Vantyghem, MC Maffi, P Kay, TW Keymeulen, B Inagaki, N Saudek, F Lehmann, R Hering, BJ |
| 2015 |
Localization of dipeptidyl peptidase-4 (CD26) to human pancreatic ducts and islet alpha cells
Diabetes Res. Clin. Pract. |
Augstein, P Naselli, G Loudovaris, T Hawthorne, WJ Campbell, P Bandala-Sanchez, E Rogers, K Heinke, P Thomas, HE Kay, TW Harrison, LC |
| 2015 |
Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release
Chem. Biol. |
Scott, JW Galic, S Graham, KL Foitzik, R Ling, NXY Dite, TA Issa, SMA Langendorf, CG Weng, QP Thomas, HE Kay, TW Birnberg, NC Steinberg, GR Kemp, BE Oakhill, JS |
| 2016 |
Perforin facilitates beta cell killing and regulates autoreactive CD8+ T cell responses to antigen in mouse models of type 1 dia
Immunol Cell Biol |
Krishnamurthy, B Graham, KL Trivedi, P Kay, TW Slattery, RM Fynch, S Thomas, HE |
| 2016 |
Human islet cells are killed by BID-independent mechanisms in response to FAS ligand
Apoptosis |
Joglekar, MV Trivedi, PM Kay, TW Hawthorne, WJ O’Connell, PJ Jenkins, AJ Hardikar, AA Thomas, HE |
| 2017 |
Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes: is change necessary?
Diabetologia |
Campbell-Thompson, ML Atkinson, MA Butler, AE Giepmans, BN von Herrath, MG Hyoty, H Kay, TW Morgan, NG Powers, AC Pugliese, A Richardson, SJ In’t Veld, PA |
| 2017 |
Transplantation sites for human and murine islets
Diabetologia |
Stokes, RA Cheng, K Lalwani, A Swarbrick, MM Thomas, HE Loudovaris, T Kay, TW Hawthorne, WJ O’Connell, PJ Gunton, JE |
| 2017 |
Cognate antigen engagement on parenchymal cells stimulates CD8(+) T cell proliferation in situ
Nat. Commun. |
Sutherland, RM Londrigan, SL Brady, JL Carrington, EM Marchingo, JM Heinzel, S Hodgkin, PD Graham, KL Kay, TW Zhan, YF Lew, AM |
| 2017 |
Repurposed JAK1/JAK2 Inhibitor Reverses Established Autoimmune Insulitis in NOD Mice
Diabetes |
Trivedi, PM Graham, KL Scott, NA Jenkins, MR Majaw, S Sutherland, RM Fynch, S Lew, AM Burns, CJ Krishnamurthy, B Brodnicki, TC Mannering, SI Kay, TW Thomas, HE |
| 2017 |
Inhibition of Y1 receptor signaling improves islet transplant outcome
Nat. Commun. |
Loh, K Shi, YC Walters, S Bensellam, M Lee, K Dezaki, K Nakata, M Ip, CK Chan, JY Gurzov, EN Thomas, HE Waibel, M Cantley, J Kay, TW Yada, T Laybutt, DR Grey, ST Herzog, H |
| 2018 |
Mortality in People With Type 1 Diabetes, Severe Hypoglycemia, and Impaired Awareness of Hypoglycemia Referred for Islet Transplantation
Transplant. Direct. |
Lee, MH Ward, GM MacIsaac, RJ Howe, K Holmes-Walker, DJ Anderson, P Radford, T Coates, PT Kay, TW O’Connell, PJ Goodman, DJ |
| 2018 |
Characterization of the Human Pancreas Side Population as a Potential Reservoir of Adult Stem Cells
Pancreas |
Augstein, P Loudovaris, T Bandala-Sanchez, E Heinke, P Naselli, G Lee, L Hawthorne, WJ Gonez, LJ Neale, AM Vaillant, F Thomas, HE Kay, TW Banakh, I Harrison, LC |
| 2019 |
Australia and New Zealand Islet and Pancreas Transplant Registry Annual Report 2018-Islet Donations, Islet Isolations, and Islet Transplants
Transplant. Direct. |
Webster, AC Hedley, JA Anderson, PF Hawthorne, WJ Radford, T Drogemuller, C Rogers, N Goodman, D Lee, MH Loudovaris, T Kelly, PJ O’Connell, PJ Holmes-Walker, DJ Kay, TW MacIsaac, RJ Ward, GM Howe, MK Coates, PT Torpy, D Roberts, A Russell, C Olakkengil, S |
| 2019 |
Replica moulded poly(dimethylsiloxane) microwell arrays induce localized endothelial cell immobilization for coculture with pancreatic islets
Biointerphases |
Burzava, ALS Forget, A Harding, FJ Cockshell, MP Penko, D Rouzaud, C Ahmadi, V Marina, PF Rojas-Canales, D Bonder, CS Coates, PTH Waibel, M Thomas, HE Kay, TW Loudovaris, T Blencowe, A Voelcker, NH |
| 2020 |
Comment on Trinh et al. Successful Treatment of Immune Checkpoint Inhibitor-Induced Diabetes With Infliximab. Diabetes Care 2019;42:e153-e154
Diabetes Care |
Galligan, A Krishnamurthy, B Kay, TW |
| 2020 |
INNATE IMMUNE SENSING AND TISSUE REMODELING OF A BIODEGRADABLE TEMPERING MATRIX SUPPORTED ISLET GRAFT
Transplantation |
Walters, SN Bailey, JG Rojas-Canales, D Drogemuller, C Loudovaris, T Kay, TW Korbutt, G Chtanova, T Greenwood, JE Coates, TP Grey, ST |
| 2020 |
The JAK1 Selective Inhibitor ABT 317 Blocks Signaling Through Interferon-gamma and Common gamma Chain Cytokine Receptors to Reverse Autoimmune Diabetes in NOD Mice
Frontiers In Immunology |
Ge, TT Jhala, G Fynch, S Akazawa, S Litwak, S Pappas, EG Catterall, T Vakil, I Long, AJ Olson, LM Krishnamurthy, B Kay, TW Thomas, HE |
| 2021 |
South Australian experience with paediatric total pancreatectomy and islet autotransplantation for PRSS1-associated hereditary pancreatitis
Medical Journal Of Australia |
Eldredge, J Couper, MR Moore, DJ Khurana, S Chen, JWC Couper, JJ Drogemuller, CJ Radford, T Kay, TW Loudovaris, T Wilks, M Coates, PT Couper, RTL |
| 2021 |
Australian experience with total pancreatectomy with islet autotransplantation to treat chronic pancreatitis
Anz Journal Of Surgery |
Bampton, TJ Holmes-Walker, DJ Drogemuller, CJ Radford, T Anderson, P Etherton, C Russell, CH Khurana, S Torpy, DJ Couper, JJ Couper, RLT Macintyre, P Neo, EL Benitez-Aguirre, P Thomas, G Loudovaris, T Thomas, HE Palmer, LJ Wu, DH Rogers, NM Williams, L Hawthorne, WJ O’Connell, PJ Kay, TW Pleass, H Chen, JW Coates, PT |
| 2021 |
Machine learning workflows identify a microRNA signature of insulin transcription in human tissues
Iscience |
Wong, WKM Joglekar, MV Saini, V Jiang, GZ Dong, CX Chaitarvornkit, A Maciag, GJ Gerace, D Farr, RJ Satoor, SN Sahu, S Sharangdhar, T Ahmed, AS Chew, YV Liuwantara, D Heng, B Lim, CK Hunter, J Januszewski, AS Sorensen, AE Akil, ASA Gamble, JR Loudovaris, T Kay, TW Thomas, HE O’Connell, PJ Guillemin, GJ Martin, D Simpson, AM Hawthorne, WJ Dalgaard, LT Ma, RCW Hardikar, AA |