Publications by Researcher: Loudovaris, T

Year	Title	Author(s)
2012	Human Islets Express a Marked Proinflammatory Molecular Signature Prior to Transplantation Cell Transplantation	Cowley, MJ Weinberg, A Zammit, NW Walters, SN Hawthorne, WJ Loudovaris, T Thomas, H Kay, T Gunton, JE Alexander, SI Kaplan, W Chapman, J O’Connell, PJ Grey, ST
2012	Residual methylprednisolone suppresses human T-cell responses to spleen, but not islet, extracts from deceased organ donors International Immunology	Joffe, M Necula, AS Chand, R McWhinney, BC Krishnamurthy, B Loudovaris, T Goodman, D Thomas, HE Kay, TWH Mannering, SI
2012	Expression of Pro- and Antiapoptotic Molecules of the Bcl-2 Family in Human Islets Postisolation Cell Transplantation	Campbell, PD Weinberg, A Chee, J Mariana, L Ayala, R Hawthorne, WJ O’Connell, PJ Loudovaris, T Cowley, MJ Kay, TW Grey, ST Thomas, HE
2013	Multicenter Australian Trial of Islet Transplantation: Improving Accessibility and Outcomes American Journal Of Transplantation	O’Connell, PJ Holmes-Walker, DJ Goodman, D Hawthorne, WJ Loudovaris, T Gunton, JE Thomas, HE Grey, ST Drogemuller, CJ Ward, GM Torpy, DJ Coates, PT Kay, TW
2013	Hypoxia-Inducible Factor-la (HIF-l alpha) Potentiates beta-Cell Survival After Islet Transplantation of Human and Mouse Islets Cell Transplantation	Stokes, RA Cheng, K Deters, N Lau, SM Hawthorne, WJ O’Connell, PJ Stolp, J Grey, S Loudovaris, T Kay, TW Thomas, HE Gonzalez, FJ Gunton, JE
2014	Glycaemic control in diabetes is restored by therapeutic manipulation of cytokines that regulated beta cell stress Nat Med	Sheng, YH Loudovaris, T Prins, JB Tong, H Chen, AC Forbes, JM Harbourt, BE Wang, R Whitehead, JP Borg, DJ Das, I Thomas, HE Hasnain, SZ Ng, CP Kay, TW McGuckin, MA
2015	Localisation of dipeptidyl peptidase-4 (CD26) to human pancreatic ducts and islet alpha cells Diabetes Res Clin Pract.	Campbell, P Kay, TW Hawthorne, WJ Thomas, HE Loudovaris, T Heinke, P Naselli, G Rogers, K Augstein, P Bandala-Sanchez, E Harrison, LC
2015	Localization of dipeptidyl peptidase-4 (CD26) to human pancreatic ducts and islet alpha cells Diabetes Res. Clin. Pract.	Augstein, P Naselli, G Loudovaris, T Hawthorne, WJ Campbell, P Bandala-Sanchez, E Rogers, K Heinke, P Thomas, HE Kay, TW Harrison, LC
2015	Proinsulin-Specific, HLA-DQ8, and HLA-DQ8-Transdimer-Restricted CD4(+) T Cells Infiltrate Islets in Type 1 Diabetes Diabetes	Pathiraja, V Kuehlich, JP Campbell, PD Krishnamurthy, B Loudovaris, T Coates, PTH Brodnicki, TC O’Connell, PJ Kedzierska, K Rodda, C Bergman, P Hill, E Purcell, AW Dudek, NL Thomas, HE Kay, TWH Mannering, SI
2015	Mouse pancreatic beta cells express MHC class II and stimulate CD4(+) T cells to proliferate Eur. J. Immunol.	Zhao, YX Scott, NA Quah, HS Krishnamurthy, B Bond, F Loudovaris, T Mannering, SI Kay, TWH Thomas, HE
2015	A comparative analysis of high-throughput platforms for validation of a circulating microRNA signature in diabetic retinopathy Sci Rep	Farr, RJ Januszewski, AS Joglekar, MV Liang, H McAulley, AK Hewitt, AW Thomas, HE Loudovaris, T Kay, TWH Jenkins, A Hardikar, AA
2015	Nuclear factor kappa B-inducing kinase activation as a mechanism of pancreatic beta cell failure in obesity J. Exp. Med.	Malle, EK Zammit, NW Walters, SN Koay, YC Wu, JM Tan, BM Villanueva, JE Brink, R Loudovaris, T Cantley, J McAlpine, SR Hesselson, D Grey, ST
2016	Regenerative Medicine: Clinical Islet Transplantation Stem Cell Biol. Regen. Med.	Thomas, HE Graham, KL Loudovaris, T Kay, TWH
2017	Transplantation sites for human and murine islets Diabetologia	Stokes, RA Cheng, K Lalwani, A Swarbrick, MM Thomas, HE Loudovaris, T Kay, TW Hawthorne, WJ O’Connell, PJ Gunton, JE
2017	IGF-2 coated porous collagen microwells for the culture of pancreatic islets J. Mat. Chem. B	Forget, A Waibel, M Rojas-Canales, DM Chen, S Kawazoe, N Harding, FJ Loudovaris, T Coates, PTH Blencowe, A Chen, G Voelcker, NH
2017	Non-invasive, in vitro analysis of islet insulin production enabled by an optical porous silicon biosensor Biosens. Bioelectron.	Chhasatia, R Sweetman, MJ Harding, FJ Waibel, M Kay, T Thomas, H Loudovaris, T Voelcker, NH
2017	Islet Transplantation Provides Superior Glycemic Control With Less Hypoglycemia Compared With Continuous Subcutaneous Insulin Infusion or Multiple Daily Insulin Injections Transplantation	Holmes-Walker, DJ Gunton, JE Hawthorne, W Payk, M Anderson, P Donath, S Loudovaris, T Ward, GM Kay, TWH O’Connell, PJ
2017	First Report of Successful Total Pancreatectomy and Islet Autotransplant in Australia Pancreas	Geyer, MC Coates, PT Khurana, S Chen, JWC Kay, TWH Balamurugan, AN Couper, JJ Radford, T Drogemuller, CJ Loudovaris, T Pathi, R Wilks, MJ Couper, RTL
2018	Characterization of the Human Pancreas Side Population as a Potential Reservoir of Adult Stem Cells Pancreas	Augstein, P Loudovaris, T Bandala-Sanchez, E Heinke, P Naselli, G Lee, L Hawthorne, WJ Gonez, LJ Neale, AM Vaillant, F Thomas, HE Kay, TW Banakh, I Harrison, LC
2018	Influenza-specific lung-resident memory T cells are proliferative and polyfunctional and maintain diverse TCR profiles J. Clin. Invest.	Pizzolla, A Nguyen, THO Sant, S Jaffar, J Loudovaris, T Mannering, SI Thomas, PG Westall, GP Kedzierska, K Wakim, LM
2018	Expression of miR-206 in human islets and its role in glucokinase regulation Am. J. Physiol.-endocrinol. Metab.	Joglekar, MV Wong, WKM Maynard, CL Umrani, MR Martin, D Loudovaris, T Thomas, HE Dalgaard, LT Hardikar, AA
2018	Oxygen-permeable microwell device maintains islet mass and integrity during shipping Endocr. Connect.	Rojas-Canales, DM Waibel, M Forget, A Penko, D Nitschke, J Harding, FJ Delalat, B Blencowe, A Loudovaris, T Grey, ST Thomas, HE Kay, TWH Drogemuller, CJ Voelcker, NH Coates, PT
2018	Loss of intra-islet heparan sulfate is a highly sensitive marker of type 1 diabetes progression in humans Plos One	Simeonovic, CJ Popp, SK Starrs, LM Brown, DJ Ziolkowski, AF Ludwig, B Bornstein, SR Wilson, JD Pugliese, A Kay, TWH Thomas, HE Loudovaris, T Choong, FJ Freeman, C Parish, CR
2018	Circulating T-FH cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity Sci. Transl. Med.	Koutsakos, M Wheatley, AK Loh, L Clemens, EB Sant, S Nussing, S Fox, A Chung, AW Laurie, KL Hurt, AC Rockman, S Lappas, M Loudovaris, T Mannering, SI Westall, GP Elliot, M Tangye, SG Wakim, LM Kent, SJ Nguyen, THO Kedzierska, K
2019	Divergent SATB1 expression across human life span and tissue compartments Immunology And Cell Biology	Nussing, S Koay, HF Sant, S Loudovaris, T Mannering, SI Lappas, M d’Udekem, Y Konstantinov, IE Berzins, SP Rimmelzwaan, GF Turner, SJ Clemens, EB Godfrey, DI Nguyen, TH Kedzierska, K
2019	Phlda3 regulates beta cell survival during stress Scientific Reports	Bensellam, M Chan, JY Lee, K Joglekar, MV Hardikar, AA Loudovaris, T Thomas, HE Jonas, JC Laybutt, DR
2019	Australia and New Zealand Islet and Pancreas Transplant Registry Annual Report 2018-Islet Donations, Islet Isolations, and Islet Transplants Transplant. Direct.	Webster, AC Hedley, JA Anderson, PF Hawthorne, WJ Radford, T Drogemuller, C Rogers, N Goodman, D Lee, MH Loudovaris, T Kelly, PJ O’Connell, PJ Holmes-Walker, DJ Kay, TW MacIsaac, RJ Ward, GM Howe, MK Coates, PT Torpy, D Roberts, A Russell, C Olakkengil, S
2019	Human gamma delta T-cell receptor repertoire is shaped by influenza viruses, age and tissue compartmentalisation Clinical & Translational Immunology	Sant, S Jenkins, MR Dash, P Watson, KA Wang, ZF Pizzolla, A Koutsakos, M Nguyen, THO Lappas, M Crowe, J Loudovaris, T Mannering, SI Westall, GP Kotsimbos, TC Cheng, AC Wakim, L Doherty, PC Thomas, PG Loh, L Kedzierska, K
2019	Replica moulded poly(dimethylsiloxane) microwell arrays induce localized endothelial cell immobilization for coculture with pancreatic islets Biointerphases	Burzava, ALS Forget, A Harding, FJ Cockshell, MP Penko, D Rouzaud, C Ahmadi, V Marina, PF Rojas-Canales, D Bonder, CS Coates, PTH Waibel, M Thomas, HE Kay, TW Loudovaris, T Blencowe, A Voelcker, NH
2019	Human CD8(+) T cell cross-reactivity across influenza A, B and C viruses Nat. Immunol.	Koutsakos, M Illing, PT Nguyen, THO Mifsud, NA Crawford, JC Rizzetto, S Eltahla, AA Clemens, EB Sant, S Chua, BY Wong, CY Allen, EK Teng, D Dash, P Boyd, DF Grzelak, L Zeng, WG Hurt, AC Barr, I Rockman, S Jackson, DC Kotsimbos, TC Cheng, AC Richards, M Westall, GP Loudovaris, T Mannering, SI Elliott, M Tangye, SG Wakim, LM Rossjohn, J Vijaykrishna, D Luciani, F Thomas, PG Gras, S Purcell, AW Kedzierska, K
2020	Ambulatory intravenous insulin and islet cell transplantation to treat severe type III insulin hypersensitivity in a patient with type 1 diabetes mellitus Clinical Case Reports	Clarke, B Loudovaris, T Radford, T Drogemuller, C Coates, PT Torpy, D
2020	E2f8 and Dlg2 genes have independent effects on impaired insulin secretion associated with hyperglycaemia Diabetologia	Yang, CH Mangiafico, SP Waibel, M Loudovaris, T Loh, K Thomas, HE Morahan, G Andrikopoulos, S
2020	HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8(+)T cells Plos Pathogens	Sant, S Quinones-Parra, SM Koutsakos, M Grant, EJ Loudovaris, T Mannering, SI Crowe, J van de Sandt, CE Rimmelzwaan, GF Rossjohn, J Gras, S Loh, L Nguyen, THO Kedzierska, K
2020	Unresponsiveness to inhaled antigen is governed by conventional dendritic cells and overridden during infection by monocytes Science Immunology	Bedford, JG Heinlein, M Garnham, AL Nguyen, THO Loudovaris, T Ge, CH Mannering, SI Elliott, M Tangye, SG Kedzierska, K Gray, DHD Heath, WR Wakim, LM
2020	INNATE IMMUNE SENSING AND TISSUE REMODELING OF A BIODEGRADABLE TEMPERING MATRIX SUPPORTED ISLET GRAFT Transplantation	Walters, SN Bailey, JG Rojas-Canales, D Drogemuller, C Loudovaris, T Kay, TW Korbutt, G Chtanova, T Greenwood, JE Coates, TP Grey, ST
2020	Facile preparation of tissue engineering scaffolds with pore size gradients using the muesli effect and their application to cell spheroid encapsulation Journal Of Biomedical Materials Research Part B-applied Biomaterials	Forget, A Rojas, D Waibel, M Pencko, D Gunenthiran, S Ninan, N Loudovaris, T Drogemuller, C Coates, PT Voelcker, NH Blencowe, A
2020	Australia and New Zealand Islet and Pancreas Transplant Registry Annual Report 2019: Islet Donations, Islet Isolations, and Islet Transplants Transplantation Direct	Webster, AC Hedley, JA Anderson, PF Hawthorne, WJ Radford, T Drogemuller, C Rogers, N Goodman, D Lee, MLH Loudovaris, T Kelly, PJ
2020	South Australian experience with pediatric total pancreatectomy and islet autotransplantation for PRSS1-associated hereditary pancreatitis Journal Of Gastroenterology And Hepatology	Mccole, J Couper, M Moore, D Khurana, S Chen, J Drogemuller, C Radford, T Couper, J Wilks, M Kay, T Loudovaris, T Coates, PT Couper, R
2020	Human Mucosal-Associated Invariant T Cells in Older Individuals Display Expanded TCR alpha beta Clonotypes with Potent Antimicrobial Responses Journal Of Immunology	Loh, L Gherardin, NA Sant, S Grzelak, L Crawford, JC Bird, NL Koay, HF van de Sandt, CE Moreira, ML Lappas, M Allen, EK Crowe, J Loudovaris, T Flanagan, KL Quinn, KM Rossjohn, J Thomas, PG Eckle, SBG McCluskey, J Godfrey, DI Kedzierska, K
2021	Integrin alpha v beta 5 heterodimer is a specific marker of human pancreatic beta cells Scientific Reports	Schiesser, JV Loudovaris, T Thomas, HE Elefanty, AG Stanley, EG
2021	Enhanced structure and function of human pluripotent stem cell-derived beta-cells cultured on extracellular matrix Stem Cells Translational Medicine	Singh, R Cottle, L Loudovaris, T Xiao, D Yang, PY Thomas, HE Kebede, MA Thorn, P
2021	Machine Learning Algorithms, Applied to Intact Islets of Langerhans, Demonstrate Significantly Enhanced Insulin Staining at the Capillary Interface of Human Pancreatic beta Cells Metabolites	Cottle, L Gilroy, I Deng, K Loudovaris, T Thomas, HE Gill, AJ Samra, JS Kebede, MA Kim, J Thorn, P
2021	Identification of mRNA and microRNA transcripts that differ in expression across islet donor sex, age and BMI Diabetologia	Wong, WKM Joglekar, MV Sorensen, AE Chew, Y Cheng, F Loudovaris, T Thomas, HE Ma, RCW Hawthorne, WJ Dalgaard, LT Hardikar, AA
2021	Structural and functional polarisation of human pancreatic beta cells in islets from organ donors with and without type 2 diabetes Diabetologia	Cottle, L Gan, WJ Gilroy, I Samra, JS Gill, AJ Loudovaris, T Thomas, HE Hawthorne, WJ Kebede, MA Thorn, P
2021	South Australian experience with paediatric total pancreatectomy and islet autotransplantation for PRSS1-associated hereditary pancreatitis Medical Journal Of Australia	Eldredge, J Couper, MR Moore, DJ Khurana, S Chen, JWC Couper, JJ Drogemuller, CJ Radford, T Kay, TW Loudovaris, T Wilks, M Coates, PT Couper, RTL
2021	Sustained subcutaneous delivery of secretome of human cardiac stem cells promotes cardiac repair following myocardial infarction Cardiovascular Research	Kompa, AR Greening, DW Kong, AM McMillan, PJ Fang, HY Saxena, R Wong, RCB Lees, JG Sivakumaran, P Newcomb, AE Tannous, BA Kos, C Mariana, L Loudovaris, T Hausenloy, DJ Lim, SY
2021	Australian experience with total pancreatectomy with islet autotransplantation to treat chronic pancreatitis Anz Journal Of Surgery	Bampton, TJ Holmes-Walker, DJ Drogemuller, CJ Radford, T Anderson, P Etherton, C Russell, CH Khurana, S Torpy, DJ Couper, JJ Couper, RLT Macintyre, P Neo, EL Benitez-Aguirre, P Thomas, G Loudovaris, T Thomas, HE Palmer, LJ Wu, DH Rogers, NM Williams, L Hawthorne, WJ O’Connell, PJ Kay, TW Pleass, H Chen, JW Coates, PT
2021	Machine learning workflows identify a microRNA signature of insulin transcription in human tissues Iscience	Wong, WKM Joglekar, MV Saini, V Jiang, GZ Dong, CX Chaitarvornkit, A Maciag, GJ Gerace, D Farr, RJ Satoor, SN Sahu, S Sharangdhar, T Ahmed, AS Chew, YV Liuwantara, D Heng, B Lim, CK Hunter, J Januszewski, AS Sorensen, AE Akil, ASA Gamble, JR Loudovaris, T Kay, TW Thomas, HE O’Connell, PJ Guillemin, GJ Martin, D Simpson, AM Hawthorne, WJ Dalgaard, LT Ma, RCW Hardikar, AA
2021	CD8(+) T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph Nature Communications	Hensen, L Illing, PT Clemens, EB Nguyen, THO Koutsakos, M van de Sandt, CE Mifsud, NA Nguyen, AT Szeto, C Chua, BY Halim, H Rizzetto, S Luciani, F Loh, L Grant, EJ Saunders, PM Brooks, AG Rockman, S Kotsimbos, TC Cheng, AC Richards, M Westall, GP Wakim, LM Loudovaris, T Mannering, SI Elliott, M Tangye, SG Jackson, DC Flanagan, KL Rossjohn, J Gras, S Davies, J Miller, A Tong, SYC Purcell, AW Kedzierska, K
2022	Case Report: Hypoglycemia Due to a Novel Activating Glucokinase Variant in an Adult - a Molecular Approach Frontiers In Endocrinology	Koneshamoorthy, A Seniveratne-Epa, D Calder, G Sawyer, M Kay, TWH Farrell, S Loudovaris, T Mariana, L McCarthy, D Lyu, RQ Liu, X Thorn, P Tong, JS Chin, LK Zacharin, M Trainer, A Taylor, S MacIsaac, RJ Sachithanandan, N Thomas, HE Krishnamurthy, B
2022	Neuropeptide Y1 receptor antagonism protects beta-cells and improves glycemic control in type 2 diabetes Molecular Metabolism	Yang, CH Ann-Onda, D Lin, XZ Fynch, S Nadarajah, S Pappas, EG Liu, X Scott, JW Oakhill, JS Galic, S Shi, YC Moreno-Asso, A Smith, C Loudovaris, T Levinger, I Eizirik, DL Laybutt, DR Herzog, H Thomas, HE Loh, K