Publications by Researcher: Graham, KL

Year	Title	Author(s)
2012	Intra-islet proliferation of cytotoxic T lymphocytes contributes to insulitis progression European Journal Of Immunology	Graham, KL Krishnamurthy, B Fynch, S Ayala-Perez, R Slattery, RM Santamaria, P Thomas, HE Kay, TWH
2012	Granzyme B Is Dispensable in the Development of Diabetes in Non-Obese Diabetic Mice Plos One	Mollah, ZU Graham, KL Krishnamurthy, B Trivedi, P Brodnicki, TC Trapani, JA Kay, TW Thomas, HE
2012	An indirect role for NK cells in a CD4(+) T-cell-dependent mouse model of type I diabetes Immunology And Cell Biology	Angstetra, E Graham, KL Zhao, YX Irvin, AE Elkerbout, L Santamaria, P Slattery, RM Kay, TW Thomas, HE
2012	Complete Diabetes Protection Despite Delayed Thymic Tolerance in NOD8.3 TCR Transgenic Mice Due to Antigen-Induced Extrathymic Deletion of T Cells Diabetes	Krishnamurthy, B Chee, J Jhala, G Fynch, S Graham, KL Santamaria, P Morahan, G Allison, J Izon, D Thomas, HE Kay, TWH
2013	Proinflammatory cytokines contribute to development and function of regulatory T cells in type 1 diabetes Translational Immunology In Asia-oceania	Thomas, HE Graham, KL Chee, J Thomas, R Kay, TW Krishnamurthy, B
2014	Effector-Memory T Cells Develop in Islets and Report Islet Pathology in Type 1 Diabetes Journal Of Immunology	Chee, J Ko, HJ Skowera, A Jhala, G Catterall, T Graham, KL Sutherland, RM Thomas, HE Lew, AM Peakman, M Kay, TWH Krishnamurthy, B
2014	Deficiency in Type I Interferon Signaling Prevents the Early Interferon-Induced Gene Signature in Pancreatic Islets but Not Type 1 Diabetes in NOD Mice Diabetes	Quah, HS Miranda-Hernandez, S Khoo, A Harding, A Fynch, S Elkerbout, L Brodnicki, TC Baxter, AG Kay, TWH Thomas, HE Graham, KL
2015	Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release Chem Biol	Ling, NXY Thomas, HE Foitzik, R Weng, QP Kemp, BE Graham, KL Langendorf, CG Steinberg, GR Galic, S Issa, SMA Birnberg, NC Scott, JW Dite, TA Kay, TW Oakhill, JS
2015	Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release Chem. Biol.	Scott, JW Galic, S Graham, KL Foitzik, R Ling, NXY Dite, TA Issa, SMA Langendorf, CG Weng, QP Thomas, HE Kay, TW Birnberg, NC Steinberg, GR Kemp, BE Oakhill, JS
2015	BIM Deficiency Protects NOD Mice From Diabetes by Diverting Thymocytes to Regulatory T Cells Diabetes	Krishnamurthy, B Chee, J Jhala, G Trivedi, P Catterall, T Selck, C Gurzov, EN Brodnicki, TC Graham, KL Wali, JA Zhan, YF Gray, D Strasser, A Allison, J Thomas, HE Kay, TWH
2016	Perforin facilitates beta cell killing and regulates autoreactive CD8+ T cell responses to antigen in mouse models of type 1 dia Immunol Cell Biol	Trivedi, P Kay, TW Slattery, RM Fynch, S Krishnamurthy, B Graham, KL Thomas, HE
2016	Regenerative Medicine: Clinical Islet Transplantation Stem Cell Biol. Regen. Med.	Thomas, HE Graham, KL Loudovaris, T Kay, TWH
2016	Rotavirus acceleration of type 1 diabetes in non-obese diabetic mice depends on type I interferon signalling Sci Rep	Pane, JA Fleming, FE Graham, KL Thomas, HE Kay, TWH Coulson, BS
2016	Perinatal tolerance to proinsulin is sufficient to prevent autoimmune diabetes Jci Insight	Jhala, G Chee, J Trivedi, PM Selck, C Gurzov, EN Graham, KL Thomas, HE Kay, TWH Krishnamurthy, B
2017	Repurposed JAK1/JAK2 Inhibitor Reverses Established Autoimmune Insulitis in NOD Mice Diabetes	Trivedi, PM Graham, KL Scott, NA Jenkins, MR Majaw, S Sutherland, RM Fynch, S Lew, AM Burns, CJ Krishnamurthy, B Brodnicki, TC Mannering, SI Kay, TW Thomas, HE
2017	Granzyme A Deficiency Breaks Immune Tolerance and Promotes Autoimmune Diabetes Through a Type I Interferon-Dependent Pathway Diabetes	Mollah, ZUA Quah, HS Graham, KL Jhala, G Krishnamurthy, B Dharma, JFM Chee, J Trivedi, PM Pappas, EG Mackin, L Chu, EPF Akazawa, S Fynch, S Hodson, C Deans, AJ Trapani, JA Chong, MMW Bird, PI Brodnicki, TC Thomas, HE Kay, TWH
2017	Cognate antigen engagement on parenchymal cells stimulates CD8(+) T cell proliferation in situ Nat. Commun.	Sutherland, RM Londrigan, SL Brady, JL Carrington, EM Marchingo, JM Heinzel, S Hodgkin, PD Graham, KL Kay, TW Zhan, YF Lew, AM
2019	IL-21 regulates SOCS1 expression in autoreactive CD8(+) T cells but is not required for acquisition of CTL activity in the islets of non-obese diabetic mice Scientific Reports	Sutherland, APR Graham, KL Papadimitriou, M Jhala, G Trivedi, P Catterall, T Fynch, S Kay, TWH Thomas, HE
2021	Deficiency of the innate immune adaptor STING promotes autoreactive T cell expansion in NOD mice Diabetologia	Akazawa, S Mackin, L Jhala, G Fynch, S Catterall, T Selck, C Graham, KL Krishnamurthy, B Pappas, EG Kwong, CTJ Sutherland, APR Kay, TWH Brodnicki, TC Thomas, HE