Publications by Researcher: Graham, KL

YearTitleAuthor(s)
2012 Intra-islet proliferation of cytotoxic T lymphocytes contributes to insulitis progression
European Journal Of Immunology
Graham, KL Krishnamurthy, B Fynch, S Ayala-Perez, R Slattery, RM Santamaria, P Thomas, HE Kay, TWH
2012 Granzyme B Is Dispensable in the Development of Diabetes in Non-Obese Diabetic Mice
Plos One
Mollah, ZU Graham, KL Krishnamurthy, B Trivedi, P Brodnicki, TC Trapani, JA Kay, TW Thomas, HE
2012 An indirect role for NK cells in a CD4(+) T-cell-dependent mouse model of type I diabetes
Immunology And Cell Biology
Angstetra, E Graham, KL Zhao, YX Irvin, AE Elkerbout, L Santamaria, P Slattery, RM Kay, TW Thomas, HE
2012 Complete Diabetes Protection Despite Delayed Thymic Tolerance in NOD8.3 TCR Transgenic Mice Due to Antigen-Induced Extrathymic Deletion of T Cells
Diabetes
Krishnamurthy, B Chee, J Jhala, G Fynch, S Graham, KL Santamaria, P Morahan, G Allison, J Izon, D Thomas, HE Kay, TWH
2013 Proinflammatory cytokines contribute to development and function of regulatory T cells in type 1 diabetes
Translational Immunology In Asia-oceania
Thomas, HE Graham, KL Chee, J Thomas, R Kay, TW Krishnamurthy, B
2014 Effector-Memory T Cells Develop in Islets and Report Islet Pathology in Type 1 Diabetes
Journal Of Immunology
Chee, J Ko, HJ Skowera, A Jhala, G Catterall, T Graham, KL Sutherland, RM Thomas, HE Lew, AM Peakman, M Kay, TWH Krishnamurthy, B
2014 Deficiency in Type I Interferon Signaling Prevents the Early Interferon-Induced Gene Signature in Pancreatic Islets but Not Type 1 Diabetes in NOD Mice
Diabetes
Quah, HS Miranda-Hernandez, S Khoo, A Harding, A Fynch, S Elkerbout, L Brodnicki, TC Baxter, AG Kay, TWH Thomas, HE Graham, KL
2015 Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release
Chem Biol
Ling, NXY Thomas, HE Foitzik, R Weng, QP Kemp, BE Graham, KL Langendorf, CG Steinberg, GR Galic, S Issa, SMA Birnberg, NC Scott, JW Dite, TA Kay, TW Oakhill, JS
2015 Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release
Chem. Biol.
Scott, JW Galic, S Graham, KL Foitzik, R Ling, NXY Dite, TA Issa, SMA Langendorf, CG Weng, QP Thomas, HE Kay, TW Birnberg, NC Steinberg, GR Kemp, BE Oakhill, JS
2015 BIM Deficiency Protects NOD Mice From Diabetes by Diverting Thymocytes to Regulatory T Cells
Diabetes
Krishnamurthy, B Chee, J Jhala, G Trivedi, P Catterall, T Selck, C Gurzov, EN Brodnicki, TC Graham, KL Wali, JA Zhan, YF Gray, D Strasser, A Allison, J Thomas, HE Kay, TWH
2016 Perforin facilitates beta cell killing and regulates autoreactive CD8+ T cell responses to antigen in mouse models of type 1 dia
Immunol Cell Biol
Trivedi, P Kay, TW Slattery, RM Fynch, S Krishnamurthy, B Graham, KL Thomas, HE
2016 Regenerative Medicine: Clinical Islet Transplantation
Stem Cell Biol. Regen. Med.
Thomas, HE Graham, KL Loudovaris, T Kay, TWH
2016 Rotavirus acceleration of type 1 diabetes in non-obese diabetic mice depends on type I interferon signalling
Sci Rep
Pane, JA Fleming, FE Graham, KL Thomas, HE Kay, TWH Coulson, BS
2016 Perinatal tolerance to proinsulin is sufficient to prevent autoimmune diabetes
Jci Insight
Jhala, G Chee, J Trivedi, PM Selck, C Gurzov, EN Graham, KL Thomas, HE Kay, TWH Krishnamurthy, B
2017 Repurposed JAK1/JAK2 Inhibitor Reverses Established Autoimmune Insulitis in NOD Mice
Diabetes
Trivedi, PM Graham, KL Scott, NA Jenkins, MR Majaw, S Sutherland, RM Fynch, S Lew, AM Burns, CJ Krishnamurthy, B Brodnicki, TC Mannering, SI Kay, TW Thomas, HE
2017 Granzyme A Deficiency Breaks Immune Tolerance and Promotes Autoimmune Diabetes Through a Type I Interferon-Dependent Pathway
Diabetes
Mollah, ZUA Quah, HS Graham, KL Jhala, G Krishnamurthy, B Dharma, JFM Chee, J Trivedi, PM Pappas, EG Mackin, L Chu, EPF Akazawa, S Fynch, S Hodson, C Deans, AJ Trapani, JA Chong, MMW Bird, PI Brodnicki, TC Thomas, HE Kay, TWH
2017 Cognate antigen engagement on parenchymal cells stimulates CD8(+) T cell proliferation in situ
Nat. Commun.
Sutherland, RM Londrigan, SL Brady, JL Carrington, EM Marchingo, JM Heinzel, S Hodgkin, PD Graham, KL Kay, TW Zhan, YF Lew, AM