Publications by Researcher: Ling, NXY

YearTitleAuthor(s)
2014 ATP sensitive bi-quinoline activator of the AMP-activated protein kinase
Biochemical And Biophysical Research Communications
Scott, JW Oakhill, JS Ling, NXY Langendorf, CG Foitzik, RC Kemp, BE Issinger, OG
2015 Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release
Chem Biol
Dite, TA Kay, TW Ling, NXY Thomas, HE Foitzik, R Weng, QP Kemp, BE Graham, KL Langendorf, CG Steinberg, GR Galic, S Issa, SMA Birnberg, NC Scott, JW Oakhill, JS
2015 Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release
Chem. Biol.
Scott, JW Galic, S Graham, KL Foitzik, R Ling, NXY Dite, TA Issa, SMA Langendorf, CG Weng, QP Thomas, HE Kay, TW Birnberg, NC Steinberg, GR Kemp, BE Oakhill, JS
2016 Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding
Nat. Commun.
Langendorf, CG Ngoei, KRW Scott, JW Ling, NXY Issa, SMA Gorman, MA Parker, MW Sakamoto, K Oakhill, JS Kemp, BE
2017 The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs
Nat. Commun.
Dite, TA Ling, NXY Scott, JW Hoque, A Galic, S Parker, BL Ngoei, KRW Langendorf, CG O’Brien, MT Kundu, M Viollet, B Steinberg, GR Sakamoto, K Kemp, BE Oakhill, JS
2018 Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK alpha 2 beta 2 gamma 1 by the Glucose Importagog SC4
Cell Chem. Biol.
Ngoei, KRW Langendorf, CG Ling, NXY Hoque, A Varghese, S Camerino, MA Walker, SR Bozikis, YE Dite, TA Ovens, AJ Smiles, WJ Jacobs, R Huang, H Parker, MW Scott, JW Rider, MH Foitzik, RC Kemp, BE Baell, JB Oakhill, JS
2018 Mitochondrial fission protein Drp1 inhibition promotes cardiac mesodermal differentiation of human pluripotent stem cells
Cell Death Discov.
Hogue, A Sivakumaran, P Bond, ST Ling, NXY Kong, AM Scott, JW Bandara, N Hernandez, D Liu, GS Wong, RCB Ryan, MT Hausenloy, DJ Kemp, BE Oakhill, JS Drew, BG Pebay, A Lim, SY
2018 AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965
J. Biol. Chem.
Dite, TA Langendorf, CG Hoque, A Galic, S Rebello, RJ Ovens, AJ Lindqvist, LM Ngoei, KRW Ling, NXY Furic, L Kemp, BE Scott, JW Oakhill, JS
2019 Phosphoproteomics reveals conserved exercise-stimulated signaling and AMPK regulation of store-operated calcium entry
Embo Journal
Nelson, ME Parker, BL Burchfield, JG Hoffman, NJ Needham, EJ Cooke, KC Naim, T Sylow, L Ling, NXY Francis, D Norris, DM Chaudhuri, R Oakhill, JS Richter, EA Lynch, GS Stockli, J James, DE
2019 ATP synthase inhibitory factor 1 (IF1), a novel myokine, regulates glucose metabolism by AMPK and Akt dual pathways
Faseb Journal
Lee, HJ Moon, J Chung, I Chung, JH Park, C Lee, JO Han, JA Kang, MJ Yoo, EH Kwak, SY Jo, G Park, W Park, J Kim, KM Lim, S Ngoei, KRW Ling, NXY Oakhill, JS Galic, S Murray-Segal, L Kemp, BE Mantzoros, CS Krauss, RM Shin, MJ Kim, HS
2020 mTORC1 directly inhibits AMPK to promote cell proliferation under nutrient stress
Nature Metabolism
Ling, NXY Kaczmarek, A Hoque, A Davie, E Ngoei, KRW Morrison, KR Smiles, WJ Forte, GM Wang, TT Lie, S Dite, TA Langendorf, CG Scott, JW Oakhill, JS Petersen, J
2020 Functional analysis of an R311C variant of Ca2+-calmodulin-dependent protein kinase kinase-2 (CaMKK2) found as a de novo mutation in a patient with bipolar disorder
Bipolar Disorders
Ling, NXY Langendorf, CG Hoque, A Galic, S Loh, K Kemp, BE Gundlach, AL Oakhill, JS Scott, JW
2020 Meteorin-like (Metrnl), as a myokine, is a therapeutic candidate for aging skeletal muscle
Australasian Journal On Ageing
Lee, JO Ling, NXY Kemp, BE Kim, HS
2020 CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins
Journal Of Biological Chemistry
Langendorf, CG O’Brien, MT Ngoei, KRW McAloon, LM Dhagat, U Hoque, A Ling, NXY Dite, TA Galic, S Loh, K Parker, MW Oakhill, JS Kemp, BE Scott, JW
2020 Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK beta 1 isoforms
Nature Metabolism
Pinkosky, SL Scott, JW Desjardins, EM Smith, BK Day, EA Ford, RJ Langendorf, CG Ling, NXY Nero, TL Loh, K Galic, S Hoque, A Smiles, WJ Ngoei, KRW Parker, MW Yan, Y Melcher, K Kemp, BE Oakhill, JS Steinberg, GR
2020 Genetic loss of AMPK-glycogen binding destabilises AMPK and disrupts metabolism
Molecular Metabolism
Hoffman, NJ Whitfield, J Janzen, NR Belhaj, MR Galic, S Murray-Segal, L Smiles, WJ Ling, NXY Dite, TA Scott, JW Oakhill, JS Brink, R Kemp, BE Hawley, JA
2020 The myokine meteorin-like (metrnl) improves glucose tolerance in both skeletal muscle cells and mice by targeting AMPK alpha 2
Febs Journal
Lee, JO Byun, WS Kang, MJ Han, JA Moon, J Shin, MJ Lee, HJ Chung, JH Lee, JS Son, CG Song, KH Kim, TW Lee, ES Kim, HM Chung, CH Ngoei, KRW Ling, NXY Oakhill, JS Galic, S Murray-Segal, L Kemp, BE Kim, KM Lim, S Kim, HS