Publications by Researcher: Ling, NXY

Year	Title	Author(s)
2014	ATP sensitive bi-quinoline activator of the AMP-activated protein kinase Biochemical And Biophysical Research Communications	Scott, JW Oakhill, JS Ling, NXY Langendorf, CG Foitzik, RC Kemp, BE Issinger, OG
2015	Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release Chem Biol	Thomas, HE Foitzik, R Weng, QP Kemp, BE Graham, KL Langendorf, CG Steinberg, GR Galic, S Issa, SMA Birnberg, NC Scott, JW Dite, TA Kay, TW Ling, NXY Oakhill, JS
2015	Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release Chem. Biol.	Scott, JW Galic, S Graham, KL Foitzik, R Ling, NXY Dite, TA Issa, SMA Langendorf, CG Weng, QP Thomas, HE Kay, TW Birnberg, NC Steinberg, GR Kemp, BE Oakhill, JS
2016	Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding Nat. Commun.	Langendorf, CG Ngoei, KRW Scott, JW Ling, NXY Issa, SMA Gorman, MA Parker, MW Sakamoto, K Oakhill, JS Kemp, BE
2017	The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs Nat. Commun.	Dite, TA Ling, NXY Scott, JW Hoque, A Galic, S Parker, BL Ngoei, KRW Langendorf, CG O’Brien, MT Kundu, M Viollet, B Steinberg, GR Sakamoto, K Kemp, BE Oakhill, JS
2018	Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK alpha 2 beta 2 gamma 1 by the Glucose Importagog SC4 Cell Chem. Biol.	Ngoei, KRW Langendorf, CG Ling, NXY Hoque, A Varghese, S Camerino, MA Walker, SR Bozikis, YE Dite, TA Ovens, AJ Smiles, WJ Jacobs, R Huang, H Parker, MW Scott, JW Rider, MH Foitzik, RC Kemp, BE Baell, JB Oakhill, JS
2018	Mitochondrial fission protein Drp1 inhibition promotes cardiac mesodermal differentiation of human pluripotent stem cells Cell Death Discov.	Hogue, A Sivakumaran, P Bond, ST Ling, NXY Kong, AM Scott, JW Bandara, N Hernandez, D Liu, GS Wong, RCB Ryan, MT Hausenloy, DJ Kemp, BE Oakhill, JS Drew, BG Pebay, A Lim, SY
2018	AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965 J. Biol. Chem.	Dite, TA Langendorf, CG Hoque, A Galic, S Rebello, RJ Ovens, AJ Lindqvist, LM Ngoei, KRW Ling, NXY Furic, L Kemp, BE Scott, JW Oakhill, JS
2019	Phosphoproteomics reveals conserved exercise-stimulated signaling and AMPK regulation of store-operated calcium entry Embo Journal	Nelson, ME Parker, BL Burchfield, JG Hoffman, NJ Needham, EJ Cooke, KC Naim, T Sylow, L Ling, NXY Francis, D Norris, DM Chaudhuri, R Oakhill, JS Richter, EA Lynch, GS Stockli, J James, DE
2019	ATP synthase inhibitory factor 1 (IF1), a novel myokine, regulates glucose metabolism by AMPK and Akt dual pathways Faseb Journal	Lee, HJ Moon, J Chung, I Chung, JH Park, C Lee, JO Han, JA Kang, MJ Yoo, EH Kwak, SY Jo, G Park, W Park, J Kim, KM Lim, S Ngoei, KRW Ling, NXY Oakhill, JS Galic, S Murray-Segal, L Kemp, BE Mantzoros, CS Krauss, RM Shin, MJ Kim, HS
2020	mTORC1 directly inhibits AMPK to promote cell proliferation under nutrient stress Nature Metabolism	Ling, NXY Kaczmarek, A Hoque, A Davie, E Ngoei, KRW Morrison, KR Smiles, WJ Forte, GM Wang, TT Lie, S Dite, TA Langendorf, CG Scott, JW Oakhill, JS Petersen, J
2020	Functional analysis of an R311C variant of Ca2+-calmodulin-dependent protein kinase kinase-2 (CaMKK2) found as a de novo mutation in a patient with bipolar disorder Bipolar Disorders	Ling, NXY Langendorf, CG Hoque, A Galic, S Loh, K Kemp, BE Gundlach, AL Oakhill, JS Scott, JW
2020	Meteorin-like (Metrnl), as a myokine, is a therapeutic candidate for aging skeletal muscle Australasian Journal On Ageing	Lee, JO Ling, NXY Kemp, BE Kim, HS
2020	CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins Journal Of Biological Chemistry	Langendorf, CG O’Brien, MT Ngoei, KRW McAloon, LM Dhagat, U Hoque, A Ling, NXY Dite, TA Galic, S Loh, K Parker, MW Oakhill, JS Kemp, BE Scott, JW
2020	Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK beta 1 isoforms Nature Metabolism	Pinkosky, SL Scott, JW Desjardins, EM Smith, BK Day, EA Ford, RJ Langendorf, CG Ling, NXY Nero, TL Loh, K Galic, S Hoque, A Smiles, WJ Ngoei, KRW Parker, MW Yan, Y Melcher, K Kemp, BE Oakhill, JS Steinberg, GR
2020	Genetic loss of AMPK-glycogen binding destabilises AMPK and disrupts metabolism Molecular Metabolism	Hoffman, NJ Whitfield, J Janzen, NR Belhaj, MR Galic, S Murray-Segal, L Smiles, WJ Ling, NXY Dite, TA Scott, JW Oakhill, JS Brink, R Kemp, BE Hawley, JA
2020	The myokine meteorin-like (metrnl) improves glucose tolerance in both skeletal muscle cells and mice by targeting AMPK alpha 2 Febs Journal	Lee, JO Byun, WS Kang, MJ Han, JA Moon, J Shin, MJ Lee, HJ Chung, JH Lee, JS Son, CG Song, KH Kim, TW Lee, ES Kim, HM Chung, CH Ngoei, KRW Ling, NXY Oakhill, JS Galic, S Murray-Segal, L Kemp, BE Kim, KM Lim, S Kim, HS
2022	Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator Biochemical Journal	Ovens, AJ Gee, YS Ling, NXY Yu, DY Hardee, JP Chung, JD Ngoei, KRW Waters, NJ Hoffman, NJ Scott, JW Loh, K Spengler, K Heller, R Parker, MW Lynch, GS Huang, F Galic, S Kemp, BE Baell, JB Oakhill, JS Langendorf, CG
2022	An AMPKa2-specific phospho-switch controls lysosomal targeting for activation Cell Reports	Morrison, KR Smiles, WJ Ling, NXY Hoque, A Shea, G Ngoei, KRW Yu, DY Murray-Segal, L Scott, JW Galic, S Kemp, BE Petersen, J Oakhill, JS
2022	Hydralazine protects the heart against acute ischaemia/reperfusion injury by inhibiting Drp1-mediated mitochondrial fission Cardiovascular Research	Kalkhoran, SB Kriston-Vizi, J Hernandez-Resendiz, S Crespo-Avilan, GE Rosdah, AA Lees, JG Da Costa, JRS Ling, NXY Holien, JK Samangouei, P Chinda, K Yap, EP Riquelme, JA Ketteler, R Yellon, DM Lim, SY Hausenloy, DJ
2022	Blocking AMPK?1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis Cell Reports	Neopane, K Kozlov, N Negoita, F Murray-Segal, L Brink, R Hoque, A Ovens, AJ Tjin, G McAloon, LM Yu, DY Ling, NXY Sanders, MJ Oakhill, JS Scott, JW Steinberg, GR Loh, K Kemp, BE Sakamoto, K Galic, S