Publications by Researcher: Dite, TA

YearTitleAuthor(s)
2014 Small Molecule Drug A-769662 and AMP Synergistically Activate Naive AMPK Independent of Upstream Kinase Signaling
Chemistry & Biology
Scott, JW Ling, NM Issa, SMA Dite, TA O’Brien, MT Chen, ZP Galic, S Langendorf, CG Steinberg, GR Kemp, BE Oakhill, JS
2015 Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release
Chem Biol
Langendorf, CG Steinberg, GR Galic, S Issa, SMA Birnberg, NC Scott, JW Dite, TA Kay, TW Ling, NXY Thomas, HE Foitzik, R Weng, QP Kemp, BE Graham, KL Oakhill, JS
2015 Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release
Chem. Biol.
Scott, JW Galic, S Graham, KL Foitzik, R Ling, NXY Dite, TA Issa, SMA Langendorf, CG Weng, QP Thomas, HE Kay, TW Birnberg, NC Steinberg, GR Kemp, BE Oakhill, JS
2015 Autophosphorylation of CaMKK2 generates autonomous activity that is disrupted by a T85S mutation linked to anxiety and bipolar disorder
Sci Rep
Scott, JW Park, E Rodriguiz, RM Oakhill, JS Issa, SMA O’Brien, MT Dite, TA Langendorf, CG Wetsel, WC Means, AR Kemp, BE
2017 The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs
Nat. Commun.
Dite, TA Ling, NXY Scott, JW Hoque, A Galic, S Parker, BL Ngoei, KRW Langendorf, CG O’Brien, MT Kundu, M Viollet, B Steinberg, GR Sakamoto, K Kemp, BE Oakhill, JS
2017 Impact of Genetic Variation on Human CaMKK2 Regulation by Ca2+-Calmodulin and Multisite Phosphorylation
Sci Rep
O’Brien, MT Oakhill, JS Ling, NMXY Langendorf, CG Hoque, A Dite, TA Means, AR Kemp, BE Scott, JW
2018 AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965
J. Biol. Chem.
Dite, TA Langendorf, CG Hoque, A Galic, S Rebello, RJ Ovens, AJ Lindqvist, LM Ngoei, KRW Ling, NXY Furic, L Kemp, BE Scott, JW Oakhill, JS
2018 Transient Expression of AMPK Heterotrimer Complexes in Mammalian Cells
Methods Mol. Biol.
Oakhill, JS Scott, JW Dite, TA
2018 Autophagy induced during apoptosis degrades mitochondria and inhibits type I interferon secretion
Cell Death Differ.
Lindqvist, LM Frank, D McArthur, K Dite, TA Lazarou, M Oakhill, JS Kile, BT Vaux, DL
2018 Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK alpha 2 beta 2 gamma 1 by the Glucose Importagog SC4
Cell Chem. Biol.
Ngoei, KRW Langendorf, CG Ling, NXY Hoque, A Varghese, S Camerino, MA Walker, SR Bozikis, YE Dite, TA Ovens, AJ Smiles, WJ Jacobs, R Huang, H Parker, MW Scott, JW Rider, MH Foitzik, RC Kemp, BE Baell, JB Oakhill, JS
2019 Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone (vol 10, 3436, 2019)
Nature Communications
Vrahnas, C Blank, M Dite, TA Tatarczuch, L Ansari, N Crimeen-Irwin, B Nguyen, H Forwood, MR Hu, YF Ikegame, M Bambery, KR Petibois, C Mackie, EJ Tobin, MJ Smyth, GK Oakhill, JS Martin, TJ Sims, NA
2019 Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone
Nature Communications
Vrahnas, C Blank, M Dite, TA Tatarczuch, L Ansari, N Crimeen-Irwinl, B Nguyen, H Forwood, MR Hu, YF Ikegame, M Bambery, KR Petibois, C Mackie, EJ Tobin, MJ Smyth, GK Oakhill, JS Martin, TJ Sims, NA
2020 CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins
Journal Of Biological Chemistry
Langendorf, CG O’Brien, MT Ngoei, KRW McAloon, LM Dhagat, U Hoque, A Ling, NXY Dite, TA Galic, S Loh, K Parker, MW Oakhill, JS Kemp, BE Scott, JW
2020 Genetic loss of AMPK-glycogen binding destabilises AMPK and disrupts metabolism
Molecular Metabolism
Hoffman, NJ Whitfield, J Janzen, NR Belhaj, MR Galic, S Murray-Segal, L Smiles, WJ Ling, NXY Dite, TA Scott, JW Oakhill, JS Brink, R Kemp, BE Hawley, JA
2020 mTORC1 directly inhibits AMPK to promote cell proliferation under nutrient stress
Nature Metabolism
Ling, NXY Kaczmarek, A Hoque, A Davie, E Ngoei, KRW Morrison, KR Smiles, WJ Forte, GM Wang, TT Lie, S Dite, TA Langendorf, CG Scott, JW Oakhill, JS Petersen, J