Publications by Researcher: Dite, TA

Year	Title	Author(s)
2014	Small Molecule Drug A-769662 and AMP Synergistically Activate Naive AMPK Independent of Upstream Kinase Signaling Chemistry & Biology	Scott, JW Ling, NM Issa, SMA Dite, TA O’Brien, MT Chen, ZP Galic, S Langendorf, CG Steinberg, GR Kemp, BE Oakhill, JS
2015	Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release Chem Biol	Foitzik, R Weng, QP Kemp, BE Graham, KL Langendorf, CG Steinberg, GR Galic, S Issa, SMA Birnberg, NC Scott, JW Dite, TA Kay, TW Ling, NXY Thomas, HE Oakhill, JS
2015	Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release Chem. Biol.	Scott, JW Galic, S Graham, KL Foitzik, R Ling, NXY Dite, TA Issa, SMA Langendorf, CG Weng, QP Thomas, HE Kay, TW Birnberg, NC Steinberg, GR Kemp, BE Oakhill, JS
2015	Autophosphorylation of CaMKK2 generates autonomous activity that is disrupted by a T85S mutation linked to anxiety and bipolar disorder Sci Rep	Scott, JW Park, E Rodriguiz, RM Oakhill, JS Issa, SMA O’Brien, MT Dite, TA Langendorf, CG Wetsel, WC Means, AR Kemp, BE
2017	The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs Nat. Commun.	Dite, TA Ling, NXY Scott, JW Hoque, A Galic, S Parker, BL Ngoei, KRW Langendorf, CG O’Brien, MT Kundu, M Viollet, B Steinberg, GR Sakamoto, K Kemp, BE Oakhill, JS
2017	Impact of Genetic Variation on Human CaMKK2 Regulation by Ca2+-Calmodulin and Multisite Phosphorylation Sci Rep	O’Brien, MT Oakhill, JS Ling, NMXY Langendorf, CG Hoque, A Dite, TA Means, AR Kemp, BE Scott, JW
2018	AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965 J. Biol. Chem.	Dite, TA Langendorf, CG Hoque, A Galic, S Rebello, RJ Ovens, AJ Lindqvist, LM Ngoei, KRW Ling, NXY Furic, L Kemp, BE Scott, JW Oakhill, JS
2018	Transient Expression of AMPK Heterotrimer Complexes in Mammalian Cells Methods Mol. Biol.	Oakhill, JS Scott, JW Dite, TA
2018	Autophagy induced during apoptosis degrades mitochondria and inhibits type I interferon secretion Cell Death Differ.	Lindqvist, LM Frank, D McArthur, K Dite, TA Lazarou, M Oakhill, JS Kile, BT Vaux, DL
2018	Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK alpha 2 beta 2 gamma 1 by the Glucose Importagog SC4 Cell Chem. Biol.	Ngoei, KRW Langendorf, CG Ling, NXY Hoque, A Varghese, S Camerino, MA Walker, SR Bozikis, YE Dite, TA Ovens, AJ Smiles, WJ Jacobs, R Huang, H Parker, MW Scott, JW Rider, MH Foitzik, RC Kemp, BE Baell, JB Oakhill, JS
2019	Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone (vol 10, 3436, 2019) Nature Communications	Vrahnas, C Blank, M Dite, TA Tatarczuch, L Ansari, N Crimeen-Irwin, B Nguyen, H Forwood, MR Hu, YF Ikegame, M Bambery, KR Petibois, C Mackie, EJ Tobin, MJ Smyth, GK Oakhill, JS Martin, TJ Sims, NA
2019	Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone Nature Communications	Vrahnas, C Blank, M Dite, TA Tatarczuch, L Ansari, N Crimeen-Irwinl, B Nguyen, H Forwood, MR Hu, YF Ikegame, M Bambery, KR Petibois, C Mackie, EJ Tobin, MJ Smyth, GK Oakhill, JS Martin, TJ Sims, NA
2020	CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins Journal Of Biological Chemistry	Langendorf, CG O’Brien, MT Ngoei, KRW McAloon, LM Dhagat, U Hoque, A Ling, NXY Dite, TA Galic, S Loh, K Parker, MW Oakhill, JS Kemp, BE Scott, JW
2020	Genetic loss of AMPK-glycogen binding destabilises AMPK and disrupts metabolism Molecular Metabolism	Hoffman, NJ Whitfield, J Janzen, NR Belhaj, MR Galic, S Murray-Segal, L Smiles, WJ Ling, NXY Dite, TA Scott, JW Oakhill, JS Brink, R Kemp, BE Hawley, JA
2020	mTORC1 directly inhibits AMPK to promote cell proliferation under nutrient stress Nature Metabolism	Ling, NXY Kaczmarek, A Hoque, A Davie, E Ngoei, KRW Morrison, KR Smiles, WJ Forte, GM Wang, TT Lie, S Dite, TA Langendorf, CG Scott, JW Oakhill, JS Petersen, J