Publications by Researcher: Holien, JK

YearTitleAuthor(s)
2012 TRIM16 Acts as an E3 Ubiquitin Ligase and Can Heterodimerize with Other TRIM Family Members
Bell, JL Malyukova, A Holien, JK Koach, J Parker, MW Kavallaris, M Marshall, GM Cheung, BB
2012 Structure of the Lectin Regulatory Domain of the Cholesterol-Dependent Cytolysin Lectinolysin Reveals the Basis for Its Lewis Antigen Specificity
Feil, SC Lawrence, S Mulhern, TD Holien, JK Hotze, EM Farrand, S Tweten, RK Parker, MW
2013 Lymphotoxin alpha induces apoptosis, necroptosis and inflammatory signals with the same potency as tumour necrosis factor
Etemadi, N Holien, JK Chau, D Dewson, G Murphy, JM Alexander, WS Parker, MW Silke, J Nachbur, U
2013 Molecular and structural insight into lysine selection on substrate and ubiquitin lysine 48 by the ubiquitin-conjugating enzyme Cdc34
Suryadinata, R Holien, JK Yang, G Parker, MW Papaleo, E Sarcevic, B
2013 Phosphorylation of Serine 779 in Fibroblast Growth Factor Receptor 1 and 2 by Protein Kinase C epsilon Regulates Ras/Mitogen-activated Protein Kinase Signaling and Neuronal Differentiation
Lonic, A Powell, JA Kong, Y Thomas, D Holien, JK Truong, N Parker, MW Guthridge, MA
2013 Disarming Bacterial Virulence through Chemical Inhibition of the DNA Binding Domain of an AraC-like Transcriptional Activator Protein
Yang, J Hocking, DM Cheng, C Dogovski, C Perugini, MA Holien, JK Parker, MW Hartland, EL Tauschek, M Robins-Browne, RM
2014 Oncogenic protein interfaces: small molecules, big challenges
Nero, TL Morton, CJ Holien, JK Wielens, J Parker, MW
2014 Synthesis, Structure-Activity Relationships and Brain Uptake of a Novel Series of Benzopyran Inhibitors of Insulin-Regulated Aminopeptidase
Mountford, SJ Albiston, AL Charman, WN Ng, L Holien, JK Parker, MW Nicolazzo, JA Thompson, PE Chai, SY
2014 A Systematic and Functional Classification of Streptococcus pyogenes That Serves as a New Tool for Molecular Typing and Vaccine Development
Sanderson-Smith, M De Oliveira, DMP Guglielmini, J McMillan, DJ Vu, T Holien, JK Henningham, A Steer, AC Bessen, DE Dale, JB Curtis, N Beall, BW Walker, MJ Parker, MW Carapetis, JR Van Melderen, L Sriprakash, KS Smeesters, PR
2015 Computational analysis of amiloride analogue inhibitors of coxsackievirus B3 RNA polymerase
Cameron, CE Jarrott, B Elliott, RW Gazina, EV Parker, MW Holien, JK Williams, SJ Petrou, S
2015 Mechanistic Scrutiny Identifies a Kinetic Role for Cytochrome b5 Regulation of Human Cytochrome P450c17 (CYP17A1, P450 17A1)
Simonov, AN Holien, JK Yeung, JCI Nguyen, AD Corbin, CJ Zheng, J Kuznetsov, VL Auchus, RJ Conley, AJ Bond, AM Parker, MW Rodgers, RJ Martin, LL
2015 Mechanistic Scrutiny Identifies a Kinetic Role for Cytochrome b5 Regulation of Human Cytochrome P450c17 (CYP17A1, P450 17A1)
Simonov, AN Holien, JK Yeung, JC Nguyen, AD Corbin, CJ Zheng, J Kuznetsov, VL Auchus, RJ Conley, AJ Bond, AM Parker, MW Rodgers, RJ Martin, LL
2015 Evolutionary comparisons predict that dimerization of human cytochrome P450 aromatase increases its enzymatic activity and effic
Martin, LL Holien, JK Mizrachi, D Corbin, CJ Conley, AJ Parker, MW Rodgers, RJ
2015 Evolutionary comparisons predict that dimerization of human cytochrome P450 aromatase increases its enzymatic activity and efficiency
Martin, LL Holien, JK Mizrachi, D Corbin, CJ Conley, AJ Parker, MW Rodgers, RJ
2015 Two-step mechanism involving active-site conformational changes regulates human telomerase DNA binding
Tomlinson, CG Moye, AL Holien, JK Parker, MW Cohen, SB Bryan, TM
2015 Crystal structure of human insulin-regulated aminopeptidase with specificity for cyclic peptides
Hermans, SJ Ascher, DB Hancock, NC Holien, JK Michell, BJ Chai, SY Morton, CJ Parker, MW
2015 A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production
Nachbur, U Stafford, CA Bankovacki, A Zhan, YF Lindqvist, LM Fiil, BK Khakham, Y Ko, HJ Sandow, JJ Falk, H Holien, JK Chau, D Hildebrand, J Vince, JE Sharp, PP Webb, AI Jackman, KA Muhlen, S Kennedy, CL Lowes, KN Murphy, JM Gyrd-Hansen, M Parker, MW Hartland, EL Lew, AM Huang, DCS Lessene, G Silke, J