Publications by Researcher: Holien, JK

YearTitleAuthor(s)
2012 TRIM16 Acts as an E3 Ubiquitin Ligase and Can Heterodimerize with Other TRIM Family Members
Plos One
Bell, JL Malyukova, A Holien, JK Koach, J Parker, MW Kavallaris, M Marshall, GM Cheung, BB
2012 Structure of the Lectin Regulatory Domain of the Cholesterol-Dependent Cytolysin Lectinolysin Reveals the Basis for Its Lewis Antigen Specificity
Structure
Feil, SC Lawrence, S Mulhern, TD Holien, JK Hotze, EM Farrand, S Tweten, RK Parker, MW
2013 Molecular and structural insight into lysine selection on substrate and ubiquitin lysine 48 by the ubiquitin-conjugating enzyme Cdc34
Cell Cycle
Suryadinata, R Holien, JK Yang, G Parker, MW Papaleo, E Sarcevic, B
2013 Lymphotoxin alpha induces apoptosis, necroptosis and inflammatory signals with the same potency as tumour necrosis factor
Febs Journal
Etemadi, N Holien, JK Chau, D Dewson, G Murphy, JM Alexander, WS Parker, MW Silke, J Nachbur, U
2013 Phosphorylation of Serine 779 in Fibroblast Growth Factor Receptor 1 and 2 by Protein Kinase C epsilon Regulates Ras/Mitogen-activated Protein Kinase Signaling and Neuronal Differentiation
Journal Of Biological Chemistry
Lonic, A Powell, JA Kong, Y Thomas, D Holien, JK Truong, N Parker, MW Guthridge, MA
2013 Disarming Bacterial Virulence through Chemical Inhibition of the DNA Binding Domain of an AraC-like Transcriptional Activator Protein
Journal Of Biological Chemistry
Yang, J Hocking, DM Cheng, C Dogovski, C Perugini, MA Holien, JK Parker, MW Hartland, EL Tauschek, M Robins-Browne, RM
2014 Oncogenic protein interfaces: small molecules, big challenges
Nature Reviews Cancer
Nero, TL Morton, CJ Holien, JK Wielens, J Parker, MW
2014 Synthesis, Structure-Activity Relationships and Brain Uptake of a Novel Series of Benzopyran Inhibitors of Insulin-Regulated Aminopeptidase
Journal Of Medicinal Chemistry
Mountford, SJ Albiston, AL Charman, WN Ng, L Holien, JK Parker, MW Nicolazzo, JA Thompson, PE Chai, SY
2014 A Systematic and Functional Classification of Streptococcus pyogenes That Serves as a New Tool for Molecular Typing and Vaccine Development
Journal Of Infectious Diseases
Sanderson-Smith, M De Oliveira, DMP Guglielmini, J McMillan, DJ Vu, T Holien, JK Henningham, A Steer, AC Bessen, DE Dale, JB Curtis, N Beall, BW Walker, MJ Parker, MW Carapetis, JR Van Melderen, L Sriprakash, KS Smeesters, PR
2015 Computational analysis of amiloride analogue inhibitors of coxsackievirus B3 RNA polymerase
J Proteomics Bioinform
Cameron, CE Jarrott, B Elliott, RW Gazina, EV Parker, MW Holien, JK Williams, SJ Petrou, S
2015 Evolutionary comparisons predict that dimerization of human cytochrome P450 aromatase increases its enzymatic activity and efficiency
J. Steroid Biochem. Mol. Biol.
Martin, LL Holien, JK Mizrachi, D Corbin, CJ Conley, AJ Parker, MW Rodgers, RJ
2015 Mechanistic Scrutiny Identifies a Kinetic Role for Cytochrome b5 Regulation of Human Cytochrome P450c17 (CYP17A1, P450 17A1)
Plos One
Simonov, AN Holien, JK Yeung, JC Nguyen, AD Corbin, CJ Zheng, J Kuznetsov, VL Auchus, RJ Conley, AJ Bond, AM Parker, MW Rodgers, RJ Martin, LL
2015 Mechanistic Scrutiny Identifies a Kinetic Role for Cytochrome b5 Regulation of Human Cytochrome P450c17 (CYP17A1, P450 17A1)
Plos One
Simonov, AN Holien, JK Yeung, JCI Nguyen, AD Corbin, CJ Zheng, J Kuznetsov, VL Auchus, RJ Conley, AJ Bond, AM Parker, MW Rodgers, RJ Martin, LL
2015 Evolutionary comparisons predict that dimerization of human cytochrome P450 aromatase increases its enzymatic activity and effic
Journal Of Steroid Biochemistry And Molecular Biology
Martin, LL Holien, JK Mizrachi, D Corbin, CJ Conley, AJ Parker, MW Rodgers, RJ
2015 Two-step mechanism involving active-site conformational changes regulates human telomerase DNA binding
Biochemical Journal
Tomlinson, CG Moye, AL Holien, JK Parker, MW Cohen, SB Bryan, TM
2015 Crystal structure of human insulin-regulated aminopeptidase with specificity for cyclic peptides
Protein Science
Hermans, SJ Ascher, DB Hancock, NC Holien, JK Michell, BJ Chai, SY Morton, CJ Parker, MW
2015 A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production
Nature Communications
Nachbur, U Stafford, CA Bankovacki, A Zhan, YF Lindqvist, LM Fiil, BK Khakham, Y Ko, HJ Sandow, JJ Falk, H Holien, JK Chau, D Hildebrand, J Vince, JE Sharp, PP Webb, AI Jackman, KA Muhlen, S Kennedy, CL Lowes, KN Murphy, JM Gyrd-Hansen, M Parker, MW Hartland, EL Lew, AM Huang, DCS Lessene, G Silke, J
2016 Mitochondrial fission - a drug target for cytoprotection or cytodestruction?
Pharmacol. Res. Perspect.
Rosdah, AA Holien, JK Delbridge, LMD Dusting, GJ Lim, SY
2016 The C-terminal extension of human telomerase reverse transcriptase is necessary for high affinity binding to telomeric DNA
Biochimie
Tomlinson, CG Holien, JK Mathias, JAT Parker, MW Bryan, TM
2017 Homodimer Model Can Resolve the Conundrum as to How Cytochrome P450 Oxidoreductase and Cytochrome b5 Compete for the Same Binding Site on Cytochrome P450c17
Curr. Protein Pept. Sci.
Holien, JK Parker, MW Conley, AJ Corbin, CJ Rodgers, RJ Martin, LL
2017 Control of Virulence Gene Expression by the Master Regulator, CfaD, in the Prototypical Enterotoxigenic Escherichia coli Strain, H10407
Front. Microbiol.
Hodson, C Yang, J Hocking, DM Azzopardi, K Chen, QY Holien, JK Parker, MW Tauschek, M Robins-Browne, RM
2018 AMP and adenosine are both ligands for adenosine 2B receptor signaling
Bioorg. Med. Chem. Lett.
Holien, JK Seibt, B Roberts, V Salvaris, E Parker, MW Cowan, PJ Dwyer, KM
2019 Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface
Cancer Research
Koach, J Holien, JK Massudi, H Carter, DR Ciampa, OC Herath, M Lim, T Seneviratne, JA Milazzo, G Murray, JE McCarroll, JA Liu, B Mayoh, C Keenan, B Stevenson, BW Gorman, MA Bell, JL Doughty, L Huttelmaier, S Oberthuer, A Fischer, M Gifford, AJ Liu, T Zhang, XL Zhu, SZ Gustafson, WC Haber, M Norris, MD Fletcher, JI Perini, G Parker, MW Cheung, BB Marshall, GM
2019 A 4-cyano-3-methylisoquinoline inhibitor of Plasmodium falciparum growth targets the sodium efflux pump PfATP4
Scientific Reports
Gilson, PR Kumarasingha, R Thompson, J Zhang, XX Sietsma Penington, J Kalhor, R Bullen, HE Lehane, AM Dans, MG de Koning-Ward, TF Holien, JK Soares da Costa, TP Hulett, MD Buskes, MJ Crabb, BS Kirk, K Papenfuss, AT Cowman, AF Abbott, BM
2020 Sequence comparisons of cytochrome P450 aromatases from Australian animals predict differences in enzymatic activity and/or efficiency
Biology Of Reproduction
Fatima, A Holien, JK Tiwari, C Parker, MW Rodgers, RJ Martin, LL
2020 Identification of RNA-Binding Proteins as Targetable Putative Oncogenes in Neuroblastoma
International Journal Of Molecular Sciences
Bell, JL Hagemann, S Holien, JK Liu, T Nagy, Z Schulte, JH Misiak, D Huttelmaier, S
2020 New perspectives on the role of Drp1 isoforms in regulating mitochondrial pathophysiology
Pharmacology & Therapeutics
Rosdah, AA Smiles, WJ Oakhill, JS Scott, JW Langendorf, CG Delbridge, LMD Holien, JK Lim, SY
2020 A structural view of PA2G4 isoforms with opposing functions in cancer
Journal Of Biological Chemistry
Stevenson, BW Gorman, MA Koach, J Cheung, BB Marshall, GM Parker, MW Holien, JK
2021 A novel combination therapy targeting ubiquitin-specific protease 5 in MYCN-driven neuroblastoma
Oncogene
Cheung, BB Kleynhans, A Mittra, R Kim, PY Holien, JK Nagy, Z Ciampa, OC Seneviratne, JA Mayoh, C Raipuria, M Gadde, S Massudi, H Wong, IPL Tan, O Gong, A Suryano, A Diakiw, SM Liu, B Arndt, GM Liu, T Kumar, N Sangfelt, O Zhu, SZ Norris, MD Haber, M Carter, DR Parker, MW Marshall, GM
2021 Role of nicotinic acetylcholine receptor subunits in the mode of action of neonicotinoid, sulfoximine and spinosyn insecticides in Drosophila melanogaster
Insect Biochemistry And Molecular Biology
Perry, T Chen, W Ghazali, R Yang, YT Christesen, D Martelli, F Lumb, C Luong, HNB Mitchell, J Holien, JK Parker, MW Sparks, TC Batterham, P
2022 Hydralazine protects the heart against acute ischaemia/reperfusion injury by inhibiting Drp1-mediated mitochondrial fission
Cardiovascular Research
Kalkhoran, SB Kriston-Vizi, J Hernandez-Resendiz, S Crespo-Avilan, GE Rosdah, AA Lees, JG Da Costa, JRS Ling, NXY Holien, JK Samangouei, P Chinda, K Yap, EP Riquelme, JA Ketteler, R Yellon, DM Lim, SY Hausenloy, DJ
2022 Mechanism of Bloom syndrome complex assembly required for double Holliday junction dissolution and genome stability
Proceedings Of The National Academy Of Sciences Of The United States Of America
Hodson, C Low, JKK van Twest, S Jones, SE Swuec, P Murphy, V Tsukada, K Fawkes, M Bythell-Douglas, R Davies, A Holien, JK O’Rourke, JJ Parker, BL Glaser, A Parker, MW Mackay, JP Blackford, AN Costa, A Deans, AJ