Publications by Researcher: Ascher, DB

Year	Title	Author(s)
2012	Crystallization and preliminary X-ray diffraction analysis of human endoplasmic reticulum aminopeptidase 2 Acta Crystallographica Section F-structural Biology And Crystallization Communications	Ascher, DB Polekhina, G Parker, MW
2012	Structural approaches to probing metal interaction with proteins Journal Of Inorganic Biochemistry	Parker, LJ Ascher, DB Gao, C Miles, LA Harris, HH Parker, MW
2013	PEGylation of interferon alpha 2 improves lymphatic exposure after subcutaneous and intravenous administration and improves antitumour efficacy against lymphatic breast cancer metastases Journal Of Controlled Release	Kaminskas, LM Ascher, DB McLeod, VM Herold, MJ Le, CP Sloan, EK Porter, CJH
2013	Structure of the N-terminal domain of human thioredoxin-interacting protein Acta Crystallographica Section D-biological Crystallography	Polekhina, G Ascher, DB Kok, SF Beckham, S Wilce, M Waltham, M
2014	Potent hepatitis C inhibitors bind directly to NS5A and reduce its affinity for RNA Scientific Reports	Ascher, DB Wielens, J Nero, TL Doughty, L Morton, CJ Parker, MW
2014	Crystallization and preliminary X-ray diffraction analysis of the Fab portion of the Alzheimer's disease immunotherapy candidate bapineuzumab complexed with amyloid-beta Acta Crystallographica Section F-structural Biology And Crystallization Communications	Crespi, GAN Ascher, DB Parker, MW Miles, LA
2014	DUET: a server for predicting effects of mutations on protein stability using an integrated computational approach Nucleic Acids Research	Pires, DEV Ascher, DB Blundell, TL
2014	Structural Studies of Streptococcus pyogenes Streptolysin O Provide Insights into the Early Steps of Membrane Penetration Journal Of Molecular Biology	Feil, SC Ascher, DB Kuiper, MJ Tweten, RK Parker, MW
2014	mCSM: predicting the effects of mutations in proteins using graph-based signatures Bioinformatics	Pires, DEV Ascher, DB Blundell, TL
2014	Do current therapeutic anti-A beta antibodies for Alzheimer's disease engage the target? Acta Neuropathologica	Watt, AD Crespi, GAN Down, RA Ascher, DB Gunn, A Perez, KA McLean, CA Villemagne, VL Parker, MW Barnham, KJ Miles, LA
2014	Anti-A beta antibody target engagement: a response to Siemers et al. Acta Neuropathologica	Watt, AD Crespi, GAN Down, RA Ascher, DB Gunn, A Perez, KA McLean, CA Villemagne, VL Parker, MW Barnham, KJ Miles, LA
2015	Crystal structure of human insulin-regulated aminopeptidase with specificity for cyclic peptides Protein Science	Hermans, SJ Ascher, DB Hancock, NC Holien, JK Michell, BJ Chai, SY Morton, CJ Parker, MW
2015	Methotrexate-Conjugated PEGylated Dendrimers Show Differential Patterns of Deposition and Activity in Tumor-Burdened Lymph Nodes after Intravenous and Subcutaneous Administration in Rats Molecular Pharmaceutics	Kaminskas, LM McLeod, VM Ascher, DB Ryan, GM Jones, S Haynes, JM Trevaskis, NL Chan, LJ Sloan, EK Finnin, BA Williamson, M Velkov, T Williams, ED Kelly, BD Owen, DJ Porter, CJH
2017	Glutathione transferase P1-1 as an arsenic drug-sequestering enzyme Protein Sci.	Parker, LJ Bocedi, A Ascher, DB Aitken, JB Harris, HH Lo Bello, M Ricci, G Morton, CJ Parker, MW
2017	Dimeric but not monomeric alpha-lactalbumin potentiates apoptosis by up regulation of ATF3 and reduction of histone deacetylase activity in primary and immortalised cells Cell. Signal.	Sharp, JA Brennan, AJ Polekhina, G Ascher, DB Lefevre, C Nicholas, KR