Publications by Researcher: Thompson, EW

2012 Mesenchymal-epithelial transition (MET) as a mechanism for metastatic colonisation in breast cancer
Cancer And Metastasis Reviews
Gunasinghe, NPAD Wells, A Thompson, EW Hugo, HJ
2012 Role of intratumoural heterogeneity in cancer drug resistance: molecular and clinical perspectives
Embo Molecular Medicine
Saunders, NA Simpson, F Thompson, EW Hill, MM Endo-Munoz, L Leggatt, G Minchin, RF Guminski, A
2012 Dormant but migratory tumour cells in desmoplastic stroma of invasive ductal carcinomas
Clinical & Experimental Metastasis
Raviraj, V Zhang, H Chien, HY Cole, L Thompson, EW Soon, L
2012 A dynamic in vivo model of epithelial-to-mesenchymal transitions in circulating tumor cells and metastases of breast cancer
Bonnomet, A Syne, L Brysse, A Feyereisen, E Thompson, EW Noel, A Foidart, JM Birembaut, P Polette, M Gilles, C
2012 Regulation of ROCK1 via Notch1 during breast cancer cell migration into dense matrices
Bmc Cell Biology
Raviraj, V Fok, S Zhao, JF Chien, HY Lyons, JG Thompson, EW Soon, L
2012 An MMP13-Selective Inhibitor Delays Primary Tumor Growth and the Onset of Tumor-Associated Osteolytic Lesions in Experimental Models of Breast Cancer
Plos One
Shah, M Huang, DX Blick, T Connor, A Reiter, LA Hardink, JR Lynch, CC Waltham, M Thompson, EW
2012 High and low mammographic density human breast tissues maintain histological differential in murine tissue engineering chambers
Breast Cancer Research And Treatment
Chew, GL Huang, D Lin, SJ Huo, C Blick, T Henderson, MA Hill, P Cawson, J Morrison, WA Campbell, IG Hopper, JL Southey, MC Haviv, I Thompson, EW
2013 An adipoinductive role of inflammation in adipose tissue engineering: key factors in the early events of neo-adipogenesis
Stem Cells Dev
Palmer, J Han, XL Thompson, EW Morrison, WA Moller, A Lilja, HE Tee, R Taylor, C Abberton, KM
2013 Breast cancer stem cells and epithelial mesenchymal plasticity - Implications for chemoresistance
Cancer Letters
Pinto, CA Widodo, E Waltham, M Thompson, EW
2013 Assessment of gene expression of intracellular calcium channels, pumps and exchangers with epidermal growth factor-induced epithelial-mesenchymal transition in a breast cancer cell line
Cancer Cell International
Davis, FM Parsonage, MT Cabot, PJ Parat, MO Thompson, EW Roberts-Thomson, SJ Monteith, GR
2013 Determining epithelial contribution to in vivo mesenchymal tumour expression signature using species-specific microarray profiling analysis of xenografts
Genetics Research
Purdom, E Restall, C Busuttil, RA Schluter, H Boussioutas, A Thompson, EW Anderson, RL Speed, TP Haviv, I
2013 Short-term single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burden
Molecular Cancer
Abubaker, K Latifi, A Luwor, R Nazaretian, S Zhu, HJ Quinn, MA Thompson, EW Findlay, JK Ahmed, N
2013 An Adipoinductive Role of Inflammation in Adipose Tissue Engineering: Key Factors in the Early Development of Engineered Soft Tissues
Stem Cells And Development
Lilja, HE Morrison, WA Han, XL Palmer, J Taylor, C Tee, R Moller, A Thompson, EW Abberton, KM
2013 Dynamic changes in high and low mammographic density human breast tissues maintained in murine tissue engineering chambers during various murine peripartum states and over time
Breast Cancer Research And Treatment
Chew, GL Huang, D Huo, CW Blick, T Hill, P Cawson, J Frazer, H Southey, MD Hopper, JL Henderson, MA Haviv, I Thompson, EW
2013 Direct repression of MYB by ZEB1 suppresses proliferation and epithelial gene expression during epithelial-to-mesenchymal transition of breast cancer cells
Breast Cancer Research
Hugo, HJ Pereira, L Suryadinata, R Drabsch, Y Gonda, TJ Gunasinghe, NPAD Pinto, C Soo, ETL van Denderen, B Hill, P Ramsay, RG Sarcevic, B Newgreen, DF Thompson, EW
2013 Molecular Profiling of Human Mammary Gland Links Breast Cancer Risk to a p27(+) Cell Population with Progenitor Characteristics
Cell Stem Cell
Choudhury, S Almendro, V Merino, VF Wu, ZH Maruyama, R Su, Y Martins, FC Fackler, MJ Bessarabova, M Kowalczyk, A Conway, T Beresford-Smith, B Macintyre, G Cheng, YK Lopez-Bujanda, Z Kaspi, A Hu, R Robens, J Nikolskaya, T Haakensen, VD Schnitt, SJ Argani, P Ethington, G Panos, L Grant, M Clark, J Herlihy, W Lin, SJ Chew, G Thompson, EW Greene-Colozzi, A Richardson, AL Rosson, GD Pike, M Garber, JE Nikolsky, Y Blum, JL Au, A Hwang, ES Tamimi, RM Michor, F Haviv, I Liu, XS Sukumar, S Polyak, K
2014 High threshold of beta 1 integrin inhibition required to block collagen I-induced membrane type-1 matrix metalloproteinase (MT1-MMP) activation of matrix metalloproteinase 2 (MMP-2)
Cancer Cell International
Borrirukwanit, K Pavasant, P Blick, T Lafleur, MA Thompson, EW
2014 Mammographic density-a review on the current understanding of its association with breast cancer
Breast Cancer Research And Treatment
Huo, CW Chew, GL Britt, KL Ingman, WV Henderson, MA Hopper, JL Thompson, EW
2014 Inhibition of the JAK2/STAT3 pathway in ovarian cancer results in the loss of cancer stem cell-like characteristics and a reduced tumor burden
Bmc Cancer
Abubaker, K Luwor, RB Zhu, HJ McNally, O Quinn, MA Burns, CJ Thompson, EW Findlay, JK Ahmed, N
2014 Induction of epithelial-mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent
Davis, FM Azimi, I Faville, RA Peters, AA Jalink, K Putney, JW Goodhill, GJ Thompson, EW Roberts-Thomson, SJ Monteith, GR
2014 Effects of Tamoxifen and oestrogen on histology and radiographic density in high and low mammographic density human breast tissues maintained in murine tissue engineering chambers
Breast Cancer Research And Treatment
Chew, GL Huo, CW Huang, D Blick, T Hill, P Cawson, J Frazer, H Southey, MC Hopper, JL Britt, K Henderson, MA Haviv, I Thompson, EW
2015 EMT process in bone metastasis
Bone Cancer: Primary Bone Cancer And Bone Metastases, 2nd Edition
Gao, DC Thompson, EW Mittal, V
2015 Epithelial mesenchymal plasticity in carcinoma metastasis
Clinical & Experimental Metastasis
Williams, ED Thompson, EW
2015 Differential effects of superoxide dismutase and superoxide dismutase/catalase mimetics on human breast cancer cells
Breast Cancer Research And Treatment
Shah, MH Liu, GS Thompson, EW Dusting, GJ Peshavariya, HM
2015 An optimised direct lysis method for gene expression studies on low cell numbers
Sci Rep
Le, AVP Huang, DX Blick, T Thompson, EW Dobrovic, A
2015 New Insights on COX-2 in Chronic Inflammation Driving Breast Cancer Growth and Metastasis
J. Mammary Gland Biol. Neoplasia
Hugo, HJ Saunders, C Ramsay, RG Thompson, EW
2015 The ubiquitin ligase Siah is a novel regulator of Zeb1 in breast cancer
Chen, A Wong, CSF Liu, MCP House, CM Sceneay, J Bowtell, DD Thompson, EW Moller, A
2015 Integrated target discovery in the EMPathy breast cancer network - multidimensional analysis of epithelial mesenchymal plasticity (EMP) in experimental systems
Clinical & Experimental Metastasis
Blick, T Phillip, GK Tomaskovic-Crook, E Goodall, G Wong, N Haviv, I Davis, M Thompson, EW
2015 Exemplary multiplex bisulfite amplicon data used to demonstrate the utility of Methpat
Wong, NC Pope, BJ Candiloro, I Korbie, D Trau, M Wong, SQ Mikeska, T van Denderen, BJW Thompson, EW Eggers, S Doyle, SR Dobrovic, A
2015 Stimulus-dependent differences in signalling regulate epithelial-mesenchymal plasticity and change the effects of drugs in breast cancer cell lines
Cell Commun. Signal.
Cursons, J Leuchowius, KJ Waltham, M Tomaskovic-Crook, E Foroutan, M Bracken, CP Redfern, A Crampin, EJ Street, I Davis, MJ Thompson, EW
2015 Increased COX-2 expression in epithelial and stromal cells of high mammographic density tissues and in a xenograft model of mammographic density
Breast Cancer Res. Treat.
Chew, GL Huo, CW Huang, D Hill, P Cawson, J Frazer, H Hopper, JL Haviv, I Henderson, MA Britt, K Thompson, EW
2015 Heterogeneity of miR-10b expression in circulating tumor cells
Sci Rep
Gasch, C Plummer, PN Jovanovic, L McInnes, LM Wescott, D Saunders, CM Schneeweiss, A Wallwiener, M Nelson, C Spring, KJ Riethdorf, S Thompson, EW Pantel, K Mellick, AS
2015 High mammographic density is associated with an increase in stromal collagen and immune cells within the mammary epithelium
Breast Cancer Res.
Huo, CW Chew, G Hill, P Huang, DX Ingman, W Hodson, L Brown, KA Magenau, A Allam, AH McGhee, E Timpson, P Henderson, MA Thompson, EW Britt, K
2016 Minimal residual disease in breast cancer: an overview of circulating and disseminated tumour cells
Clin. Exp. Metastasis
Tachtsidis, A McInnes, LM Jacobsen, N Thompson, EW Saunders, CM
2016 Altered purinergic receptor-Ca2+ signaling associated with hypoxia-induced epithelial-mesenchymal transition in breast cancer cells
Mol. Oncol.
Azimi, I Beilby, H Davis, FM Marcial, DL Kenny, PA Thompson, EW Roberts-Thomson, SJ Monteith, GR
2016 Human glandular organoid formation in murine engineering chambers after collagenase digestion and flow cytometry isolation of normal human breast tissue single cells
Cell Biol. Int.
Huo, CW Huang, DX Chew, GL Hill, P Vohora, A Ingman, WV Glynn, DJ Godde, N Henderson, MA Thompson, EW Britt, KL
2016 Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer
Skalamera, D Dahmer-Heath, M Stevenson, AJ Pinto, C Shah, ET Daignault, SM Said, NABM Davis, M Haass, NK Williams, ED Hollier, BG Thompson, EW Gabrielli, B Gonda, TJ
2016 Mammographically dense human breast tissue stimulates progression to invasive lesions and metastasis
Breast Cancer Res.
Huo, CW Waltham, M Khoo, C Fox, SB Hill, P Chen, S Chew, GL Price, JT Nguyen, CH Williams, ED Henderson, M Thompson, EW Britt, KL
2017 Epithelial requirement for in vitro proliferation and xenograft growth and metastasis of MDA-MB-468 human breast cancer cells: oncogenic rather than tumor-suppressive role of E-cadherin
Breast Cancer Res.
Hugo, HJ Gunasinghe, NPAD Hollier, BG Tanaka, T Blick, T Toh, A Hill, P Gilles, C Waltham, M Thompson, EW
2019 Interrogation of Phenotypic Plasticity between Epithelial and Mesenchymal States in Breast Cancer
Journal Of Clinical Medicine
Bhatia, S Monkman, J Blick, T Pinto, C Waltham, M Nagaraj, SH Thompson, EW
2019 Human-specific RNA analysis shows uncoupled epithelial-mesenchymal plasticity in circulating and disseminated tumour cells from human breast cancer xenografts
Clinical & Experimental Metastasis
Tachtsidis, A Le, AVP Blick, T Gunasinghe, D De Sousa, E Waltham, M Dobrovic, A Thompson, EW
2020 Integrin alpha-2 and beta-1 expression increases through multiple generations of the EDW01 patient-derived xenograft model of breast cancer-insight into their role in epithelial mesenchymal transition in vivo gained from an in vitro model system
Breast Cancer Research
Wafai, R Williams, ED de Souza, E Simpson, PT Reed, AEM Kutasovic, JR Waltham, M Snell, CE Blick, T Thompson, EW Hugo, HJ
2020 Identifying Therapies to Combat Epithelial Mesenchymal Plasticity-Associated Chemoresistance to Conventional Breast Cancer Therapies Using An shRNA Library Screen
Bhatia, S Blick, T Pinto, C Waltham, M Monkman, J Ivanova, E Pollock, PM Nagaraj, SH Wiegmans, AP Haviv, I Simpson, KJ Thompson, EW