Publications by Researcher: Poulton, IJ

YearTitleAuthor(s)
2012 Contrasting roles of leukemia inhibitory factor in murine bone development and remodeling involve region-specific changes in vascularization
Journal Of Bone And Mineral Research
Poulton, IJ McGregor, NE Pompolo, S Walker, EC Sims, NA
2012 Sustained RANKL Response to Parathyroid Hormone in Oncostatin M Receptor-Deficient Osteoblasts Converts Anabolic Treatment to a Catabolic Effect In Vivo
Journal Of Bone And Mineral Research
Walker, EC Poulton, IJ McGregor, NE Ho, PWM Allan, EH Quach, JM Martin, TJ Sims, NA
2012 Strain-Dependent Differences in Bone Development, Myeloid Hyperplasia, Morbidity and Mortality in Ptpn2-Deficient Mice
Plos One
Wiede, F Chew, SH van Vliet, C Poulton, IJ Kyparissoudis, K Sasmono, T Loh, K Tremblay, ML Godfrey, DI Sims, NA Tiganis, T
2013 Ciliary Neurotrophic Factor Inhibits Bone Formation and Plays a Sex-Specific Role in Bone Growth and Remodeling (vol 86, pg 261, 2010)
Calcified Tissue International
McGregor, NE Poulton, IJ Walker, EC Pompolo, S Quinn, JMW Martin, TJ Sims, NA
2014 gp130 signalling in osteocytes is required for the anabolic action of parathyroid hormone
Journal Of Endocrinology
McGregor, NE Poulton, IJ Brennan, HJ Johnson, RW Martin, TJ Standal, T Walker, EC Sims, NA
2014 gp130 in late osteoblasts and osteocytes is required for PTH-induced osteoblast differentiation
Journal Of Endocrinology
Standal, T Johnson, RW McGregor, NE Poulton, IJ Ho, PWM Martin, TJ Sims, NA
2014 The Primary Function of gp130 Signaling in Osteoblasts Is To Maintain Bone Formation and Strength, Rather Than Promote Osteoclast Formation
Journal Of Bone And Mineral Research
Johnson, RW Brennan, HJ Vrahnas, C Poulton, IJ McGregor, NE Standal, T Walker, EC Koh, TT Nguyen, H Walsh, NC Forwood, MR Martin, TJ Sims, NA
2014 EphrinB2 signaling in osteoblasts promotes bone mineralization by preventing apoptosis
Faseb Journal
Tonna, S Takyar, FM Vrahnas, C Crimeen-Irwin, B Ho, PWM Poulton, IJ Brennan, HJ McGregor, NE Allan, EH Nguyen, H Forwood, MR Tatarczuch, L Mackie, EJ Martin, TJ Sims, NA
2015 RAR gamma is a negative regulator of osteoclastogenesis
J. Steroid Biochem. Mol. Biol.
Green, AC Poulton, IJ Vrahnas, C Hausler, KD Walkley, CR Wu, JY Martin, TJ Gillespie, MT Chandraratna, RAS Quinn, JMW Sims, NA Purton, LE
2015 Glycoprotein130 (Gp130)/interleukin-6 (IL-6) signalling in osteoclasts promotes bone formation in periosteal and trabecular bone
Bone
Johnson, RW McGregor, NE Brennan, HJ Crimeen-Irwin, B Poulton, IJ Martin, TJ Sims, NA
2015 Ubiquitous expression of the Pik3ca(H1047R) mutation promotes hypoglycemia, hypoinsulinemia, and organomegaly
Faseb Journal
Kinross, KM Montgomery, KG Mangiafico, SP Hare, LM Kleinschmidt, M Bywater, MJ Poulton, IJ Vrahnas, C Henneicke, H Malaterre, J Waring, PM Cullinane, C Sims, NA McArthur, GA Andrikopoulos, S Phillips, WA
2016 Chondrocytic ephrin B2 promotes cartilage destruction by osteoclasts in endochondral ossification
Development
Tonna, S Poulton, IJ Taykar, F Ho, PWM Tonkin, B Crimeen-Irwin, B Tatarczuch, L McGregor, NE Mackie, EJ Martin, TJ Sims, NA
2016 Loss of G(s)alpha in the Postnatal Skeleton Leads to Low Bone Mass and a Blunted Response to Anabolic Parathyroid Hormone Therapy
J. Biol. Chem.
Sinha, P Aarnisalo, P Chubb, R Poulton, IJ Guo, J Nachtrab, G Kimura, T Swami, S Saeed, H Chen, M Weinstein, LS Schipani, E Sims, NA Kronenberg, HM Wu, JY
2016 Murine Oncostatin M Acts via Leukemia Inhibitory Factor Receptor to Phosphorylate Signal Transducer and Activator of Transcription 3 (STAT3) but Not STAT1, an Effect That Protects Bone Mass
J. Biol. Chem.
Walker, EC Johnson, RW Hu, YF Brennan, HJ Poulton, IJ Zhang, JG Jenkins, BJ Smyth, GK Nicola, NA Sims, NA
2017 Bone corticalization requires local SOCS3 activity and is promoted by androgen action via interleukin-6
Nat. Commun.
Cho, DC Brennan, HJ Johnson, RW Poulton, IJ Gooi, JH Tonkin, BA McGregor, NE Walker, EC Handelsman, DJ Martin, TJ Sims, NA
2018 IL-6 trans-signalling mediates trabecular, but not cortical, bone loss after ovariectomy
Bone
Lazzaro, L Tonkin, BA Poulton, IJ McGregor, NE Ferlin, W Sims, NA
2018 Absence of Calcitriol Causes Increased Lactational Bone Loss and Lower Milk Calcium but Does Not Impair Post-lactation Bone Recovery in Cyp27b1 Null Mice
J. Bone Miner. Res.
Gillies, BR Ryan, BA Tonkin, BA Poulton, IJ Ma, Y Kirby, BJ St-Arnaud, R Sims, NA Kovacs, CS
2018 Autocrine and Paracrine Regulation of the Murine Skeleton by Osteocyte-Derived Parathyroid Hormone-Related Protein
J. Bone Miner. Res.
Ansari, N Ho, PWM Crimeen-Irwin, B Poulton, IJ Brunt, AR Forwood, MR Pajevic, PD Gooi, JH Martin, TJ Sims, NA
2018 Osteoblasts Are Rapidly Ablated by Virus-Induced Systemic Inflammation following Lymphocytic Choriomeningitis Virus or Pneumonia Virus of Mice Infection in Mice
J. Immunol.
Maltby, S Lochrin, AJ Bartlett, B Tay, HL Weaver, J Poulton, IJ Plank, MW Rosenberg, HF Sims, NA Foster, PS
2019 IL-6 exhibits both cis- and trans-signaling in osteocytes and osteoblasts, but only trans-signaling promotes bone formation and osteoclastogenesis
Journal Of Biological Chemistry
McGregor, NE Murat, M Elango, J Poulton, IJ Walker, EC Crimeen-Irwin, B Ho, PWM Gooi, JH Martin, TJ Sims, NA
2020 Testing Bone Formation Induction by Calvarial Injection Assay in vivo
Bio-protocol
McGregor, NE Poulton, IJ Walker, EC Sims, NA
2020 Cortical bone maturation in mice requires SOCS3 suppression of gp130/STAT3 signalling in osteocytes
Elife
Walker, EC Truong, K McGregor, NE Poulton, IJ Isojima, T Gooi, JH Martin, TJ Sims, NA
2020 Interaction between osteocyte SOCS3-dependent signaling and the bone marrow microenvironment maintains cortical bone integrity
Journal Of Bone And Mineral Research
Isojima, T Walker, EC Crimeen-Irwin, B Poulton, IJ McGregor, NE Gooi, JH Martin, TJ Sims, NA
2021 Bone Geometry Is Altered by Follistatin-Induced Muscle Growth in Young Adult Male Mice
Jbmr Plus
Chan, ASM McGregor, NE Poulton, IJ Hardee, JP Cho, EHJ Martin, TJ Gregorevic, P Sims, NA Lynch, GS
2021 Dmp1Cre-directed knockdown of parathyroid hormone-related protein (PTHrP) in murine decidua is associated with a life-long increase in bone mass, width, and strength in male progeny
Journal Of Bone And Mineral Research
Ansari, N Isojima, T Crimeen-Irwin, B Poulton, IJ McGregor, NE Ho, PWM Forwood, MR Kovacs, CS Dimitriadis, E Gooi, JH Martin, TJ Sims, NA
2022 STAT3 Hyperactivation Due to SOCS3 Deletion in Murine Osteocytes Accentuates Responses to Exercise- and Load-Induced Bone Formation
Journal Of Bone And Mineral Research
McGregor, NE Walker, EC Chan, ASM Poulton, IJ Cho, EHJ Windahl, SH Sims, NA