Publications in 2015

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2015 Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release
Kemp, BE Dite, TA Steinberg, GR Ling, NXY Birnberg, NC Foitzik, R Kay, TW Graham, KL Thomas, HE Galic, S Weng, QP Scott, JW Langendorf, CG Issa, SMA Oakhill, JS
2015 Localisation of dipeptidyl peptidase-4 (CD26) to human pancreatic ducts and islet alpha cells
Rogers, K Bandala-Sanchez, E Campbell, P Hawthorne, WJ Loudovaris, T Kay, TW Naselli, G Thomas, HE Augstein, P Heinke, P Harrison, LC
2015 Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes
Thomas, HE Mehdi, AM Irvine, KM Pang, D Hamilton-Williams, EE Harris, M Thomas, R
2015 Ciliary neutrotrophic factor has intrinsic and extrinsic roles in regulating B cell differentiation and bone structure
Quach, JM King, HA Jovic, T White, KE Walkley, CR Askmyr, M Smeets, MF Baker, EK Maluenda, AC Purton, LE
2015 Computational analysis of amiloride analogue inhibitors of coxsackievirus B3 RNA polymerase
Elliott, RW Gazina, EV Holien, JK Parker, MW Williams, SJ Cameron, CE Jarrott, B Petrou, S
2015 Crystal structure of the lysine specific protease Kgp, isolated from Porphyromonas gingivalis, a target for improved oral health
Michell, BJ Seers, CA Gorman, MA Reynolds, EC Cross, KJ Huq, NL Feil, SC Parker, MW
2015 An adipogenic gel for surgical reconstruction of the subcutaneous fat layer in a rat model
Poon, CJ Debels, H Gerrand, YW Morrison, WA Abberton, KM Mitchell, GM
2015 Pancreatic PYY Is Critical in the Control of Insulin Secretion and Glucose Homeostasis in Female Mice
Lee, K Bensellam, M Loh, K Shi, YC Zhai, L Lau, J Laybutt, R Luzuriaga, J Cantley, J Herzog, H
2015 BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells
Baker, EK Taylor, S Gupte, A Sharp, PP Walia, M Walsh, NC Zannettino, ACW Chalk, AM Burns, CJ Walkley, CR
2015 Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity
Ford, RJ Fullerton, MD Pinkosky, SL Day, EA Scott, JW Oakhill, JS Bujak, AL Smith, BK Crane, JD Blumer, RM Marcinko, K Kemp, BE Gerstein, HC Steinberg, GR
2015 Stimulus-dependent differences in signalling regulate epithelial-mesenchymal plasticity and change the effects of drugs in breast cancer cell lines
Cursons, J Leuchowius, KJ Waltham, M Tomaskovic-Crook, E Foroutan, M Bracken, CP Redfern, A Crampin, EJ Street, I Davis, MJ Thompson, EW
2015 HIF-1 alpha is required for hematopoietic stem cell mobilization and 4-prolyl hydroxylase inhibitors enhance mobilization by stabilizing HIF-1 alpha
Forristal, CE Nowlan, B Jacobsen, RN Barbier, V Walkinshaw, G Walkley, CR Winkler, IG Levesque, JP
2015 RANKL/OPG; Critical role in bone physiology
Martin, TJ Sims, NA
2015 Evidence-Informed Clinical Practice Recommendations for Treatment of Type 1 Diabetes Complicated by Problematic Hypoglycemia
Choudhary, P Rickels, MR Senior, PA Vantyghem, MC Maffi, P Kay, TW Keymeulen, B Inagaki, N Saudek, F Lehmann, R Hering, BJ
2015 AMPK Activation of Muscle Autophagy Prevents Fasting-Induced Hypoglycemia and Myopathy during Aging
Bujak, AL Crane, JD Lally, JS Ford, RJ Kang, SJ Rebalka, IA Green, AE Kemp, BE Hawke, TJ Schertzer, JD Steinberg, GR